Pan-tissue mitochondrial phenotyping reveals lower OXPHOS expression and function across cancer typesarticle Published on 2023-10-052024-09-05 Journal: Burma Med J [Category] update2024, [키워드] Cancer metabolism energy metabolism [DOI] 10.1038/s41598-023-43963-5 PMC 바로가기 [Article Type] article
Amino acid metabolism in health and diseasearticle Published on 2023-09-132024-09-05 Journal: Signal Transduction and Targeted Therapy [Category] update2024, [키워드] Cancer metabolism [DOI] 10.1038/s41392-023-01569-3 PMC 바로가기 [Article Type] article
Fasting mimicking diet in mice delays cancer growth and reduces immunotherapy-associated cardiovascular and systemic side effectsarticle Published on 2023-09-082024-09-05 Journal: Nature Communications [Category] update2024, [키워드] Cancer immunotherapy Cancer metabolism [DOI] 10.1038/s41467-023-41066-3 PMC 바로가기 [Article Type] article
Dynamic interplay between sortilin and syndecan-1 contributes to prostate cancer progressionarticle Published on 2023-08-182024-09-05 Journal: Burma Med J [Category] update2024, [키워드] Cancer metabolism Endosomes Prostate cancer Tumour biomarkers [DOI] 10.1038/s41598-023-40347-7 PMC 바로가기 [Article Type] article
p53 promotes peroxisomal fatty acid β-oxidation to repress purine biosynthesis and mediate tumor suppressionarticle Published on 2023-02-072024-09-05 Journal: Cell Death & Disease [Category] update2024, [키워드] Cancer metabolism Colon cancer [DOI] 10.1038/s41419-023-05625-2 PMC 바로가기 [Article Type] article
Endogenous formaldehyde scavenges cellular glutathione resulting in redox disruption and cytotoxicityArticle Published on 2022-02-082022-10-04 Journal: Nature Communications [Category] 유전자 메커니즘, [키워드] alcohol antioxidant Apoptosis bone marrow failure Caenorhabditis elegan Cancer metabolism cause cellular cellular damage Chemical genetics coding contributing to crosslinking cytotoxicity DNA DNA damage DNA repair endogenous enzyme formaldehyde functional GSH human cell Mechanisms of disease metabolic pathways metabolite Mutation oxidative stress Patient prevented PROTECT question raising Redox imbalance reduced resulting syndrome Therapeutic benefit thiol group thought Toxicity Trigger underlie yielding [DOI] 10.1038/s41467-022-28242-7 PMC 바로가기 [Article Type] Article
Hyperpolarised 13 C-MRI identifies the emergence of a glycolytic cell population within intermediate-risk human prostate cancerArticle Published on 2022-01-242022-10-04 Journal: Nature Communications [Category] 바이오마커, 진단, [키워드] accompanied Cancer Cancer imaging Cancer metabolism cell population changes in clinically Cohort correlated detect disease enzyme epithelial expression identify immunohistochemistry independent indolent Intravenous injection Lactate lactate dehydrogenase LDHA LDHB magnetic resonance imaging measure metabolism MRI mRNA expression observé phenotype Prostate Prostate cancer transcriptomics tumour [DOI] 10.1038/s41467-022-28069-2 PMC 바로가기 [Article Type] Article
Targeting the complex I and III of mitochondrial electron transport chain as a potentially viable option in liver cancer managementArticle Published on 2021-10-142023-08-30 Journal: Cell Death Discovery [Category] E형 간염, [키워드] Cancer metabolism Targeted therapies [DOI] 10.1038/s41420-021-00675-x PMC 바로가기 [Article Type] Article
Clinical significance of small molecule metabolites in the blood of patients with different types of liver injuryArticle Published on 2021-06-022023-06-03 Journal: Scientific Reports [Category] B형 간염, [키워드] Cancer metabolism Molecular biology [DOI] 10.1038/s41598-021-91164-9 PMC 바로가기 [Article Type] Article
DHODH and cancer: promising prospects to be exploredReview Published on 2021-05-102022-10-31 Journal: Cancer & Metabolism [Category] COVID-19, [키워드] association Cancer Cancer cells Cancer metabolism Cancer therapy de novo De novo pyrimidine biosynthesis DHODH DHODH inhibitors dihydroorotate dehydrogenase disease Effect enzyme Evidence Human inhibitor mechanism Mitochondria mitochondrial multiple sclerosis pathway rheumatoid arthritis therapeutic target Therapies Treatment Tumor tumor progression [DOI] 10.1186/s40170-021-00250-z PMC 바로가기 [Article Type] Review