Low-dose corticosteroid therapy for cardiogenic shock in adults (COCCA): study protocol for a randomized controlled trial성인의 심인성 쇼크에 대한 저용량 코르티코스테로이드 요법(COCCA): 무작위 대조 시험을 위한 연구 프로토콜Study Protocol Published on 2022-01-032022-09-10 Journal: Trials [Category] SARS, 임상, [키워드] 1:1 Administered Adrenal insufficiency Adult patients all-cause mortality alteration Analysis approach Cardiogenic shock catecholamine caused characterized conducted consequence control group Corticosteroid corticosteroid therapy corticotropin discharge double-blind dysfunction effective Effectiveness Endothelial dysfunction Endpoint etomidate evaluate Evidence Fludrocortisone France Hydrocortisone hypothalamic-pituitary-adrenal axis ICU IMPROVE include Inflammation intensive care unit intention-to-treat basis intravenous intravenous bolus life-threatening low dose low-dose low-dose corticosteroid morbidity Myocardial infarction outcome Parallel Arm pathophysiological Patient Placebo placebo-controlled trial primary endpoint profile randomization Randomized Randomized controlled trial Randomly recruit recruited secondary Secondary endpoints Shock stimulation test Study protocol subgroup therapeutic therapy tissue treat Treatment treatment group Trial Trial registration [DOI] 10.1186/s13063-021-05947-6 PMC 바로가기 [Article Type] Study Protocol
Pathophysiology of Takotsubo Cardiomyopathy: Reopened DebateTakotsubo 심근병증의 병태생리: 재개된 논쟁Review Published on 2021-07-012022-09-11 Journal: Texas Heart Institute journal [Category] SARS, 변종, [키워드] Acetylcholine addition assumed atherosclerotic catecholamine catecholamines/metabolism clinical observations complex Coronary artery Coronary artery disease coronary artery disease/complications coronary spasm coronary vasospasm/complications/physiopathology COVID-19 pandemic debate dominant Effect Effects emotional emotional stress explain feature incidence initial left ventricle manifestation Manifestations mechanism men metabolism modulate Myocardial Myocardial ischemia obstruction Pain pathophysiologic physically plaque plaque, atherosclerotic/physiopathology predominant progressed proof risk Risk factors Sex sex differences spasm spastic Stress Takotsubo cardiomyopathy takotsubo cardiomyopathy/blood/etiology/physiopathology variant ventricular ventricular function, left/drug effects. women [DOI] 10.14503/THIJ-20-7490 PMC 바로가기 [Article Type] Review
A fatal toxic shock-like syndrome post COVID-19 infection in a child어린이의 COVID-19 감염 후 치명적인 독성 쇼크 유사 증후군Case Reports Published on 2021-06-022022-09-10 Journal: Italian Journal of Pediatrics [Category] MERS, 바이오마커, [키워드] abdominal pain affected Cardiac output catecholamine Child children condition coronavirus disease Coronavirus disease 2019 Coronavirus infection Corticosteroid COVID-19 COVID-19 infection Definition echocardiography Ejection Ejection fraction Fever fresh frozen plasma frozen plasma heart failure High dose Hypotension Immunoglobulin Inflammatory inflammatory markers intensive care Intravenous immunoglobulin Kawasaki disease lesions life-threatening lymphopenia Manifestations MIS-C Multi-system inflammatory syndrome multiple organ dysfunction multiple organ failure organ dysfunction outcome Patient pediatric pericardial effusion persistent fever plasma presenting receiving SARS-COV-2 infection Severe case severe cases Shock Symptom syndrome Toxic shock syndrome TSS: toxic shock syndrome valvular Vasopressor vasopressors [DOI] 10.1186/s13052-021-01070-z PMC 바로가기 [Article Type] Case Reports
Playing around the anaerobic threshold during COVID-19 pandemic: advantages and disadvantages of adding bouts of anaerobic work to aerobic activity in physical treatment of individuals with obesityCOVID-19 전염병 동안 혐기성 역치 주변에서 놀기: 비만 환자의 물리적 치료에서 유산소 활동에 무산소 운동을 추가하는 것의 장점과 단점Review Published on 2021-05-282022-09-10 Journal: Acta Diabetologica [Category] MERS, SARS, 치료기술, [키워드] Adding aerobic Aerobic exercise aims anaerobic Anaerobic threshold Blood body mass cardiorespiratory catecholamine Comorbidities Comorbidity Complication concerning COVID-19 COVID-19 pandemic debate diet disadvantage Diseases Disposal Effect exercise Final growth hormone High-intensity IMPROVE increase in individual intensity Lactate lactic acid limit management metabolism methodology milestone moderate normal weight number of comorbidity obesity overcome performed physical physical activity Physical exercise potential benefit potential benefits Prognosis re-evaluation reduction rehabilitation related diseases respiratory Result subject systemic threshold Treatment Variation Ventilation ventilatory [DOI] 10.1007/s00592-021-01747-1 PMC 바로가기 [Article Type] Review
CytoResc – “CytoSorb” Rescue for critically ill patients undergoing the COVID-19 Cytokine Storm: A structured summary of a study protocol for a randomized controlled trialCytoResc – COVID-19 사이토카인 폭풍을 겪고 있는 중환자를 위한 "CytoSorb" 구조: 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약Letter Published on 2020-06-262022-08-13 Journal: Trials [Category] SARS, 임상, [키워드] 1:1 24 hour 24 hours Acute kidney injury Acute respiratory failure Administered Analysis Antibiotics arterial arterial pressure Bacterial Berlin blinded Blinding block blocks Blood C-reactive protein C-reactive protein (CRP catecholamine cause center Chain Reaction Charité clinical Clinical course Clinical practice clinical trials clinically clinician comparator concentrations condition conducted contraindication COVID-19 COVID-19 patient COVID-19 patients Critical care Critically ill critically ill COVID-19 patients Critically ill patient critically ill patients cytokine Cytokine storm Cytokines Cytosorb CytoSorb® data set death defined dissemination dose element elevated Endpoint extracorporeal cytokine elimination feasibility Filter Formal Germany Hemodynamics hospital discharge Hospitalization hospitalized patient hospitalized patients hyperinflammation Hyperinflammatory ICU-treatment ICUs IIb IL-6 IMPROVE Inc. Inclusion inclusion criteria indication intensive care unit intensive care units interleukin interleukin-6 intervention effect mean arterial pressure mechanical ventilation molecular weight Mortality multicenter New Norepinephrine number objective observational study occur Open-label other conditions outcome parallel group participant Patient patients PCR PCT performed phase pilot study polymerase chain polymerase chain reaction polystyrene positive pressure Prevent primary endpoint procalcitonin Proinflammatory cytokine proinflammatory cytokines protocol randomization Randomized Randomized controlled trial reason for receive recruited reducing Registered registry renal replacement therapy replacement therapy rescue Respiratory failure Safety Safety assessment Sample size SARS-CoV-2 secondary Secondary outcomes Shock shown Standard of care statistician status stratified Study design Study protocol Suspected therapy toxin Treatment Trial Trial registration USA vasoplegic shock Vasopressor vasopressors website [DOI] 10.1186/s13063-020-04501-0 PMC 바로가기 [Article Type] Letter
Dopamine-induced sulfatase and its regulator are required for Salmonella enterica serovar Typhimurium pathogenesisarticle Published on 2019-03-312024-09-01 Journal: Microbiology [Category] 살모넬라증, [키워드] catecholamine Dopamine Salmonella sulfatase zebrafish [Article Type] article
Dopamine Is a Siderophore-Like Iron Chelator That Promotes Salmonella enterica Serovar Typhimurium Virulence in Mice도파민은 쥐에서 살모넬라 엔테리카 세로바르 타이피무리움의 병원성을 촉진하는 사이더로포어 유사 철 킬레이터이다.Article Published on 2019-02-052024-07-29 Journal: mBio [Category] 살모넬라증, [키워드] catecholamine Dopamine iron qseC Salmonella Typhimurium Sepsis [DOI] 10.1128/mBio.02624-18 PMC 바로가기