Identification of a Spike-Specific CD8 + T-Cell Epitope Following Vaccination Against the Middle East Respiratory Syndrome Coronavirus in HumansBrief Report Viruses Published on 2024-08-152024-09-05 Journal: Nanoscale [Category] update2024, [키워드] CD8+ T cells epitope MERS-CoV MVA Vaccine Viral vector [DOI] 10.1093/infdis/jiad612 PMC 바로가기 [Article Type] Brief Report Viruses
Severe Tick-Borne Encephalitis (TBE) in a Patient with X-Linked Agammaglobulinemia; Treatment with TBE Virus IgG Positive Plasma, Clinical Outcome and T Cell ResponsesResearch Published on 2024-04-272024-09-05 Journal: Journal of Clinical Immunology [Category] update2024, [키워드] CD8+ T cells immunodeficiency Neutralising Antibodies tetramers tick-borne encephalitis X-linked agammaglobulinemia [DOI] 10.1007/s10875-024-01718-5 PMC 바로가기 [Article Type] Research
A Broad-Spectrum Multi-Antigen mRNA/LNP-Based Pan-Coronavirus Vaccine Induced Potent Cross-Protective Immunity Against Infection and Disease Caused by Highly Pathogenic and Heavily Spike-Mutated SARS-CoV-2 Variants of Concern in the Syrian Hamster ModelArticle Published on 2024-02-152024-09-05 Journal: bioRxiv [Category] update2024, [키워드] CD4+ T cells CD8+ T cells COVID-19 cross-protective pan-coronavirus vaccine SARS-CoV-2 variants of concern [DOI] 10.1101/2024.02.14.580225 PMC 바로가기 [Article Type] Article
Fighting flu: novel CD8 + T‐cell targets are required for future influenza vaccinesReview Published on 2024-02-142024-09-05 Journal: Clinical & Translational Immunology [Category] update2024, [키워드] CD8+ T cells Epitopes HLA‐I Influenza Vaccines [DOI] 10.1002/cti2.1491 PMC 바로가기 [Article Type] Review
Regulation of Mitochondrial Metabolism by Hepatitis B VirusReview Published on 2023-11-302024-09-05 Journal: Viruses [Category] update2024, [키워드] CD8+ T cells hepatic macrophages Hepatitis B virus innate immune response mitochondrial metabolism mitophagy oxidative phosphorylation [DOI] 10.3390/v15122359 PMC 바로가기 [Article Type] Review
Cross-Protection Induced by Highly Conserved Human B, CD4 +, and CD8 + T Cell Epitopes-Based Coronavirus Vaccine Against Severe Infection, Disease, and Death Caused by Multiple SARS-CoV-2 Variants of ConcernArticle Published on 2023-05-242024-09-05 Journal: bioRxiv [Category] update2024, [키워드] antibodies CD4+ T cells CD8+ T cells COVID-19 Epitopes Immunity immunopathology SARS-CoV-2 SL-CoVs Vaccine variants of concern [DOI] 10.1101/2023.05.24.541850 PMC 바로가기 [Article Type] Article
ChAdOx1 nCoV‐19 vaccination generates spike‐specific CD8 + T cells in aged miceOutstanding Observation Published on 2023-05-062024-09-05 Journal: Immunology and Cell Biology [Category] update2024, [키워드] aging CD8+ T cells Immunity SARS‐CoV‐2 vaccination [DOI] 10.1111/imcb.12645 PMC 바로가기 [Article Type] Outstanding Observation
Robust SARS-CoV-2 T cell responses with common TCRαβ motifs toward COVID-19 vaccines in patients with hematological malignancy impacting B cellsArticle Published on 2023-03-272024-09-05 Journal: Cell Reports Medicine [Category] update2024, [키워드] antibody-secreting cells B cells CD4+ T cells CD8+ T cells COVID-19 vaccines hematology memory T cells SARS-CoV-2 T follicular helper cells tetramer-specific [DOI] 10.1016/j.xcrm.2023.101017 PMC 바로가기 [Article Type] Article
Chronic Inflammation Might Protect Hemodialysis Patients From Severe COVID-19만성 염증은 심각한 COVID-19로부터 혈액 투석 환자를 보호할 수 있습니다Immunology Published on 2022-02-212022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 치료기술, [키워드] B cell B cells CD25 CD3 CD38 CD4 CD8 CD8+ T cells chronic chronic inflammation comparable Control control patient coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient COVID-19 patients cytokine Cytokines dependent on disease severity Dynamics effector memory excess mortality expected FOXP3 hallmark hallmarks Hemodialysis hemodialysis patients Hospitalized ICU admission immune Immune phenotype immune system Inflammation inflammatory state less moderate Mortality Patient patients patients with moderate patients without COVID-19 PCR-confirmed COVID-19 Peripheral blood Phenotypes Plasma cytokine PROTECT regulated regulatory T cells Result severe COVID-19 significantly significantly increased subtype Subtypes Symptoms T cell T cells TEMRA Th1 Th17 was performed while with COVID-19 [DOI] 10.3389/fimmu.2022.821818 PMC 바로가기 [Article Type] Immunology
Genome-Wide B-Cell, CD4 + and CD8 + T-Cell Epitopes, that are Highly Conserved Between Human and Animal Coronaviruses, Identified from SARS-CoV-2 as Targets for Pre-Emptive Pan-Coronavirus VaccinesArticle Published on 2021-11-252023-07-01 Journal: Journal of immunology (Baltimore, Md. : 1950) [Category] SARS, [키워드] antibodies CD4+ T cells CD8+ T cells COVID-19 Epitopes Immunity immunopathology pan-coronavirus SARS-CoV-2 SL-CoVs Vaccine [DOI] 10.4049/jimmunol.2001438 PMC 바로가기 [Article Type] Article