Cellular Senescence and Extracellular Vesicles in the Pathogenesis and Treatment of Obesity—A Narrative ReviewReview Published on 2024-07-202024-09-05 Journal: International Journal of Molecular Sciences [Category] update2024, [키워드] adiponectin aging AMPK autophagy cellular senescence DDR epigenome ER stress Exosomes Extracellular vesicles hypertrophic obesity insulin resistance lipotoxicity metabolic syndrome miRNA NEFA obesogenic environment p53 ROS SASP Senolytic SIRT-1 VAT Western-type diet [DOI] 10.3390/ijms25147943 PMC 바로가기 [Article Type] Review
Integrative analyses of genes associated with oxidative stress and cellular senescence in triple-negative breast cancerResearch Article Published on 2024-07-162024-09-05 Journal: Heliyon [Category] update2024, [키워드] bioinformatics cellular senescence oxidative stress triple-negative breast cancer Tumor immune microenvironment [DOI] 10.1016/j.heliyon.2024.e34524 PMC 바로가기 [Article Type] Research Article
Global scientific trends on exosomes therapy for osteoporosis from 2004 to 2023: A bibliometric and visualized analysis4700 Published on 2024-07-122024-09-05 Journal: Medicine [Category] update2024, [키워드] bibliometric analysis cellular senescence Exosomes Mesenchymal stem cells osteoblasts Osteoclasts Osteoporosis [DOI] 10.1097/MD.0000000000038835 PMC 바로가기 [Article Type] 4700
Role of the Senescence-Associated Factor Dipeptidyl Peptidase 4 in the Pathogenesis of SARS-CoV-2 InfectionOriginal Article Published on 2024-05-072024-09-05 Journal: Aging and Disease [Category] update2024, [키워드] cellular senescence COVID-19 DDP4 Infection [DOI] 10.14336/AD.2023.0812 PMC 바로가기 [Article Type] Original Article
Uncovering a unique pathogenic mechanism of SARS-CoV-2 omicron variant: selective induction of cellular senescenceResearch Paper Published on 2023-12-152024-09-05 Journal: Aging (Albany NY) [Category] update2024, [키워드] cellular senescence lung airway cells SARS-CoV-2 variant of concern [DOI] 10.18632/aging.205297 PMC 바로가기 [Article Type] Research Paper
Determining the feasibility of characterising cellular senescence in human skeletal muscle and exploring associations with muscle morphology and physical function at different ages: findings from the MASS_Lifecourse StudyOriginal Article Published on 2023-07-112024-09-05 Journal: GeroScience [Category] update2024, [키워드] cellular senescence Human skeletal muscle ageing Muscle morphology Physical function sarcopenia [DOI] 10.1007/s11357-023-00869-4 PMC 바로가기 [Article Type] Original Article
A novel anti-HBV agent, E-CFCP, restores Hepatitis B virus (HBV)-induced senescence-associated cellular marker perturbation in human hepatocytesArticle Published on 2023-05-012023-06-09 Journal: Virus research [Category] B형 간염, [키워드] cellular senescence Hepatitis B virus Human hepatocytes nucleoside analogs p21(CIP1). [DOI] 10.1016/j.virusres.2023.199094
A novel anti-HBV agent, E -CFCP, restores Hepatitis B virus (HBV)-induced senescence-associated cellular marker perturbation in human hepatocytesarticle Published on 2023-03-232024-09-05 Journal: Virus research [Category] update2024, [키워드] cellular senescence Hepatitis B virus Human hepatocytes nucleoside analogs p21 [DOI] 10.1016/j.virusres.2023.199094 PMC 바로가기 [Article Type] article
Interactomics: Dozens of Viruses, Co-evolving With Humans, Including the Influenza A Virus, may Actively Distort Human AgingArticle Published on 2023-02-032023-06-14 Journal: Molecular Biology and Evolution [Category] Fulltext, 신종인플루엔자, [키워드] age-distorters cellular senescence co-evolution evolutionary theories of aging Protein–protein interaction viruses [DOI] 10.1093/molbev/msad012 PMC 바로가기
Repurposing SGLT-2 Inhibitors to Target Aging: Available Evidence and Molecular MechanismsArticle Published on 2022-10-142022-11-15 Journal: International Journal of Molecular Sciences [Category] 신약개발, 진단, [키워드] accompanied activity addition aging all-cause mortality animal model animal models available data benefit Biomarker blunt caloric restriction calories cardiovascular diseases Cardiovascular outcomes cellular senescence clinical study clinical trials Compound COVID-19 decrease diabetes driver drug drugs employment Evidence Fatty acid feature Glucose heart failure humans IL-6 independent inflammaging Inflammasome inhibitor inhibitors intrinsic Kidney disease low-grade inflammation Meta-analysis modulating modulation molecular Mortality nutrient-sensing pathways observational studies outcomes pathway Patient promote provided repurposing selected senescence sodium-glucose cotransporter 2 inhibitors. substrates suggested Support systemic effects systemic level target Urine [DOI] 10.3390/ijms232012325 PMC 바로가기