Dual effects of supplemental oxygen on pulmonary infection, inflammatory lung injury, and neuromodulation in aging and COVID-19
Review article
[키워드] activating
Activation
acute lung injury
acute respiratory distress syndrome (ARDS)
age
aging
Analysis
Anti-inflammatory
antioxidant
ARDS
attenuate
Biomarkers
Blood oxygen saturation
Brain
cause
caused
cellular
cellular damage
Central nervous system
Cholinergic anti-inflammatory pathway
chronic inflammation
clinical
Clinical outcome
COVID-19
COVID-19 patient
COVID-19 patients
death
decrease
Defense
distress
dysregulated
Effect
function
functions
humans
hyperinflammation
IMPROVE
increase in
infected with SARS-CoV-2
infections
Inflammation
inflammatory lung injury
Inflammatory response
inhibiting
Innate immunity
likelihood
lung
lung cells
Lung inflammation
macrophages
master regulator
Mitochondria
morbidity and mortality
oxidative
oxidative stress
oxygen
Oxygen therapy
pathway
positive correlation
positively correlated
Postmortem
prolonged exposure
Pulmonary infection
reactive oxygen specy
receiving
receptor
regulate
regulated
resulting
ROS
Safe
Sepsis
shown
Signaling
supplemental oxygen
Supplemental oxygen therapy
susceptibility
syndrome
Therapeutic approach
Toxicity
treat
α7 nicotinic acetylcholine receptor
α7nAChR
[DOI] 10.1016/j.freeradbiomed.2022.08.004 [Article Type] Review article
[DOI] 10.1016/j.freeradbiomed.2022.08.004 [Article Type] Review article