Exploring the Pathophysiology of Long COVID: The Central Role of Low-Grade Inflammation and Multisystem InvolvementReview Published on 2024-06-092024-09-05 Journal: International Journal of Molecular Sciences [Category] update2024, [키워드] chronic inflammation Diagnostic strategies Inflamm-aging Long COVID low-grade inflammation PASC pathophysiology Personalized medicine Post COVID-19 condition systemic inflammation [DOI] 10.3390/ijms25126389 PMC 바로가기 [Article Type] Review
Overnutrition and Lipotoxicity: Impaired Efferocytosis and Chronic Inflammation as Precursors to Multifaceted Disease PathogenesisReview Published on 2024-04-062024-09-05 Journal: Biology [Category] update2024, [키워드] chronic inflammation Efferocytosis lipotoxicity overnutrition oxidative stress [DOI] 10.3390/biology13040241 PMC 바로가기 [Article Type] Review
TLR7 promotes smoke-induced experimental lung damage through the activity of mast cell tryptasearticle Published on 2023-11-142024-09-05 Journal: Nature Communications [Category] update2024, [키워드] chronic inflammation chronic obstructive pulmonary disease Inflammatory diseases Toll-like receptors [DOI] 10.1038/s41467-023-42913-z PMC 바로가기 [Article Type] article
A comprehensive SARS-CoV-2 and COVID-19 review, Part 2: host extracellular to systemic effects of SARS-CoV-2 infectionReview Article Published on 2023-11-082024-09-05 Journal: European Journal of Human Genetics [Category] update2024, [키워드] chronic inflammation Diagnostic markers pathology viral infection [DOI] 10.1038/s41431-023-01462-1 PMC 바로가기 [Article Type] Review Article
Balancing the functions of DNA extracellular traps in intracellular parasite infections: implications for host defense, disease pathology and therapyarticle Published on 2023-07-202024-09-05 Journal: Cell Death & Disease [Category] update2024, [키워드] Cell death and immune response chronic inflammation [DOI] 10.1038/s41419-023-05994-8 PMC 바로가기 [Article Type] article
Chronic inflammation, neutrophil activity, and autoreactivity splits long COVIDarticle Published on 2023-07-142024-09-05 Journal: Nature Communications [Category] update2024, [키워드] Autoimmunity chronic inflammation SARS-CoV-2 Systems analysis [DOI] 10.1038/s41467-023-40012-7 PMC 바로가기 [Article Type] article
A SARS-CoV-2-specific CAR-T-cell model identifies felodipine, fasudil, imatinib, and caspofungin as potential treatments for lethal COVID-19article Published on 2023-03-022024-09-05 Journal: Cellular & molecular immunology [Category] update2024, [키워드] Anti-inflammation CAR-T chronic inflammation COVID-19 High-throughput screening NF-κB pathway SARS-CoV-2 viral infection [DOI] 10.1038/s41423-023-00985-3 PMC 바로가기 [Article Type] article
Detection of SARS-CoV-2 viral proteins and genomic sequences in human brainstem nucleiarticle Published on 2023-02-132024-09-05 Journal: NPJ Parkinson's Disease [Category] update2024, [키워드] Brain chronic inflammation Neurodegenerative diseases Neuroimmunology [DOI] 10.1038/s41531-023-00467-3 PMC 바로가기 [Article Type] article
Hyperbaric oxygen for treatment of long COVID-19 syndrome (HOT-LoCO): protocol for a randomised, placebo-controlled, double-blind, phase II clinical trialArticle Published on 2022-11-022022-11-15 Journal: BMJ Open [Category] SARS, 진단, [키워드] approved assessment baseline Blood Cardiology case sery chronic fatigue syndrome chronic inflammation clinical clinical trial cognitive collected common COVID-19 defined domain double-blind dysfunction Effect effective Efficacy endothelial function Ethics evaluate fatigue healthy subject hyperbaric oxygen hypothese immunology IMPROVE Inconclusive independent individual initial institutional review board Long malaise mechanism monitoring board oxygen Oxygen therapy pandemic Patient peer-reviewed performed physical placebo-controlled placebo-controlled clinical trial positive Potential treatment product protocol Quality of life Questionnaires randomised rehabilitation medicine respiratory medicine (see thoracic medicine) secondary endpoint suggested survey Swedish Symptom syndrome the primary endpoint Treatment Trial VASCULAR MEDICINE. [DOI] 10.1136/bmjopen-2022-061870 PMC 바로가기
Toward a big picture of COVID-19Article Published on 2022-10-012022-11-15 Journal: Pharmacology Research & Perspectives [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] addition available data benefit caused chronic inflammation clinical trial Corona COVID-19 Critical Culture cybernetics driven by drug eco ecosystem effort ENhance Epidemiology Evidence executive explain explicit Governance handling Inflammation knowledge Laboratory limitation Local lockdown management media mutant National occurred organization pandemic Pandemics pathology Perspective problem reflect Regulation Research SARS-CoV2 suggested System Treatment zoonoses zoonosis [DOI] 10.1002/prp2.996 PMC 바로가기