Conformational characterization of the mammalian-expressed SARS-CoV-2 recombinant receptor binding domain, a COVID-19 vaccinearticle Published on 2023-05-082024-09-05 Journal: Biological Research [Category] update2024, [키워드] characterization Circular dichroism COVID-19 vaccines Fluorescence RBD [DOI] 10.1186/s40659-023-00434-5 PMC 바로가기 [Article Type] article
The cytoplasmic tail of influenza A/H1N1 virus hemagglutinin is β-structuralArticle Published on 2022-07-012023-06-23 Journal: Journal of biomolecular structure & dynamics [Category] 신종인플루엔자, [키워드] 3D homology modeling Circular dichroism Fluorescence spectroscopy Influenza virus hemagglutinin cytoplasmic tail intrinsic disorder. [DOI] 10.1080/07391102.2020.1860827
Binding of raloxifene to human complement fragment 5a ( h C5a): a perspective on cytokine storm and COVID19Article Published on 2022-02-012022-10-04 Journal: Journal of biomolecular structure & dynamics [Category] COVID19(2023년), SARS, 신약개발, [키워드] approach binding binding affinity C5a C5aR Carprofen Circular dichroism combination therapy complement conformational COVID19 cytokine Cytokine storm Diseases downstream expressed FDA-approved drugs glycoprotein Human Infection Inflammatory diseases inherent management molecular molecular dynamics Neutralizing Pathogenesis Perspective plasticity pleiotropic Polypharmacology precursor pro-inflammatory raloxifene. receptor Stress Support synergistic targets tissues triggering undergo [DOI] 10.1080/07391102.2020.1820381 PMC 바로가기 [Article Type] Article
The role of human C5a as a non-genomic target in corticosteroid therapy for management of severe COVID19중증 COVID19 관리를 위한 코르티코스테로이드 요법에서 비-게놈 표적으로서 인간 C5a의 역할Article Published on 2021-06-012022-09-12 Journal: Computational biology and chemistry [Category] MERS, SARS, 신약개발, 진단, [키워드] activate acute respiratory syndrome amplified appear binding C3a C5a chemoattractant Circular Circular dichroism clinical evidence Colchicine combination therapy complement complement system contribute Coronavirus-2 corticosteroid therapy Corticosteroids COVID19 Cytokine storm Dexamethasone drug Effect Fluorescence globe Host immunomodulator indicate Inflammatory management moderate modulating molecular dynamics morbidity and mortality Neutralizing non-genomic non-specific pathophysiological Pathways physiological Polypharmacology positive Prednisone Prednisone. probe Prophylactic PROTECT reducing repurposing Safe SARS-CoV2 severity Signaling significantly small molecule drug triggered triggering Vaccine while [DOI] 10.1016/j.compbiolchem.2021.107482 PMC 바로가기 [Article Type] Article
Preformulation Characterization and the Effect of Ionic Excipients on the Stability of a Novel DB Fusion Proteinarticle Published on 2021-01-312024-09-01 Journal: Pathogens [Category] 세균성이질, [키워드] Accelerated stability Anionic excipients Biologics stability Biophysical characterization Biophysical stability Cationic excipients Circular dichroism differential scanning calorimetry Fluorescence spectroscopy Forced degradation Protein formulation protein interactions Shigella type III secretion system vaccine delivery vaccine formulation [Article Type] article
Heparin Inhibits Cellular Invasion by SARS-CoV-2: Structural Dependence of the Interaction of the Spike S1 Receptor-Binding Domain with HeparinArticle Published on 2020-12-232023-07-02 Journal: Thrombosis and haemostasis [Category] SARS, [키워드] Circular dichroism coronavirus COVID-19 heparin Molecular modelling RBD S1 SARS-CoV-2 spike surface plasmon resonance [DOI] 10.1055/s-0040-1721319 PMC 바로가기
Selection and structural analysis of the NY25 peptide – A vaccine candidate from hemagglutinin of swine-origin Influenza H1N1Article Published on 2018-12-012023-06-23 Journal: Microbial pathogenesis [Category] 신종인플루엔자, [키워드] Circular dichroism Fluorescence quenching hemagglutinin Influenza pandemic H1N1 Synthetic vaccine. [DOI] 10.1016/j.micpath.2018.09.004
Biophysical comparison of diphtheria and tetanus toxins with the formaldehyde-detoxified toxoids, the main components of diphtheria and tetanus vaccines디프테리아 및 파상풍 독소와 포름알데히드 해독된 독소의 생물물리학적 비교, 디프테리아 및 파상풍 백신의 주요 성분Article Published on 2017-11-172024-08-18 Journal: Virulence [Category] 파상풍, [키워드] Circular dichroism differential scanning fluorimetry Diphtheria MALDI-TOF mass spectrometry small-angle X-ray scattering Tetanus toxin toxoid Vaccine
Key Residues of S. flexneri OmpA Mediate Infection by Bacteriophage Sf6S. flexneri OmpA의 주요 잔여물은 박테리오파지 Sf6에 의한 감염을 매개한다.journal-article Published on 2015-05-012024-07-30 Journal: J Mater Chem B [Category] 세균성이질, [키워드] Circular dichroism Outer membrane proteins phage attachment Plaque assay virus receptor [DOI] 10.1016/j.jmb.2015.03.012 [Article Type] journal-article