Caveolin-1 mediates blood-brain barrier permeability, neuroinflammation, and cognitive impairment in SARS-CoV-2 infectionArticle Published on 2024-06-092024-09-05 Journal: Journal of neuroimmunology [Category] update2024, [키워드] blood-brain barrier Brain caveolin-1 CD3 claudin-5 endothelial Neuroinflammation Novel object recognition SARS-CoV-2 T cell [DOI] 10.1016/j.jneuroim.2024.578309 PMC 바로가기 [Article Type] Article
Zonulin and claudin-5 levels in multisystem inflammatory syndrome and SARS-CoV-2 infection in childrenArticle Published on 2022-09-012023-07-09 Journal: Journal of paediatrics and child health [Category] COVID19(2023년), [키워드] children claudin-5 multisystem inflammatory syndrome (MIS-C) SARS-COV-2 infection zonulin [DOI] 10.1111/jpc.16033 PMC 바로가기
Effect of Ergothioneine on 7-Ketocholesterol-Induced Endothelial Injury7-케토콜레스테롤에 의한 내피 손상에 대한 에르고티오네인의 효과Article Published on 2021-03-012022-09-11 Journal: Neuromolecular medicine [Category] 신약개발, [키워드] 7-Ketocholesterol addition animals Anti-inflammatory anti-inflammatory effect Anti-inflammatory effects antioxidant Apoptosis Bacteria blood-brain barrier Blood–brain barrier Brain cardiovascular disease Cell cell viability cholesterol claudin claudin-5 CNS complications coronavirus COVID-19 COX2 cross Cyclooxygenase Cytokines Dementia diabetes diet Diseases dose-dependent Effect Eicosanoids Endothelial cell endothelial cells enzymatic activity Ergothioneine excitotoxicity Extracellular Free Free radicals fungi Human brain humans IL-1β IL-6 IL-8 increase in increases in Incubation induce Inflammation inhibitor management mRNA expression Mushrooms Necrosis neurodegenerative Neuroinflammation neurologic Neurovascular Neutralizing NF-kB nucleus nutraceutical oxidative stress Oxysterols Patient pro-inflammatory cytokines produced protective effect Proteins reduced significantly stroke thought tight junction Tight junction proteins TNF-α unlikely Vascular vascular dementia viability ZO-1 zonula zonula occludens [DOI] 10.1007/s12017-020-08620-4 PMC 바로가기 [Article Type] Article
Molecular Insights into the Thrombotic and Microvascular Injury in Placental Endothelium of Women with Mild or Severe COVID-19경증 또는 중증 COVID-19를 가진 여성의 태반 내피에서 혈전 및 미세혈관 손상에 대한 분자적 통찰력Article Published on 2021-02-102022-09-11 Journal: Cells [Category] MERS, 바이오마커, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus binding cadherin cells chorionic chorionic villus claudin claudin-5 clinical manifestation clinical manifestations coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 decidua decrease Deleterious disease severity endothelial Endothelium expression healthy controls histological analysis immunofluorescence increases in insight Mild Mild disease Placenta placental Placentas pregnant women receptor ACE2 respiratory reveal SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe cases severe COVID-19 the disease thrombosis variety Vascular VE-cadherin vessels villus von Willebrand factor with COVID-19 with mild disease women [DOI] 10.3390/cells10020364 PMC 바로가기 [Article Type] Article
Erg mediates downregulation of claudin-5 in the brain endothelium of a murine experimental model of cerebral malariaarticle Published on 2019-09-302024-09-01 Journal: FEBS Letters [Category] 말라리아, [키워드] cerebral malaria claudin-5 ERG permeability transcriptional regulation [Article Type] article
Cell-selective knockout and 3D confocal image analysis reveals separate roles for astrocyte-and endothelial-derived CCL2 in neuroinflammationResearch Published on 2014-01-212023-08-30 Journal: Journal of Neuroinflammation [Category] E형 간염, [키워드] 3D confocal imaging astrocytes blood–brain barrier Brain microvascular endothelial cells CCL2 Central nervous system claudin-5 experimental autoimmune encephalomyelitis Neuroinflammation [DOI] 10.1186/1742-2094-11-10 PMC 바로가기 [Article Type] Research