Clinical Effectiveness of Regdanvimab Treatment for Mild-to-Moderate COVID-19: A Retrospective Cohort StudyResearch article Published on 2022-05-162022-10-05 Journal: Current Therapeutic Research [Category] 신약개발, 임상, 치료법, [키워드] Adverse reaction Clin clinical coronavirus disease COVID-19 CT-P59 death deaths Deterioration discharged efficacy end point Exp Fever Hospitalization indicate mechanical ventilation median time Mild-to-moderate oxygen oxygen saturation p value Patient patients deteriorating patients with COVID-19 performed peripheral capillary phase Placebo Prevent proportion reduced regdanvimab Remdesivir required Result retrospective cohort study Retrospective study risk SARS-CoV-2 single hospital SOC Standard of care sustained treated Two patient [DOI] 10.1016/j.curtheres.2022.100675 [Article Type] Research article
The Possible Role of Bruton Tyrosine Kinase Inhibitors in the Treatment of COVID-19: A ReviewReview article Published on 2021-12-152022-10-05 Journal: Current Therapeutic Research [Category] 바이오마커, 변종, 치료법, [키워드] anti-inflammatory cytokines Anti-inflammatory effects Bruton tyrosine kinase inhibitor BTK BTK inhibitor caused Clin clinician Complication Coronavirus disease 2019 COVID-19 cytokine level Cytokine release syndrome Cytokines develop disease Effect Effectiveness Elsevier evaluate Exp immune response Inflammation Inflammatory cytokines information journal kinase less management medication Mortality Novel coronavirus objective pandemic Pathogenesis pathogenesis of COVID-19 pathway Patient patients patients with COVID-19 provide receiving reduce Result review role SARS-CoV-2 Serum level Severe case severe respiratory illness Signaling Spread subsequent Support the disease treating COVID-19 Treatment tyrosine Web of Science [DOI] 10.1016/j.curtheres.2021.100658 [Article Type] Review article
Finding the Middle Ground with the Clinical Laboratory’s Role in SARS-CoV-2 Genomic SurveillanceSARS-CoV-2 게놈 감시에서 임상 실험실의 역할로 중간 지점 찾기Article Published on 2021-11-182022-09-11 Journal: Journal of Clinical Microbiology [Category] SARS, 변종, 유전자 메커니즘, [키워드] Accuracy acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 added Alpha approach assist characterized Clin clinical clinical sample clinical samples coronavirus Delta Delta variants dominant effort finding flexible generate genomic Genomic surveillance highlight identify journal Laboratory lineages medium Microbiology middle multiplex Mutation Next-generation sequencing NGS polymorphism public health Rapid replacement role SARS-CoV-2 sequence sequenced single-nucleotide single-nucleotide polymorphism SNP Surveillance the United State Threats United States variant variants [DOI] 10.1128/JCM.01816-21 PMC 바로가기 [Article Type] Article
Angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers: potential allies in the COVID-19 pandemic instead of a threat?Cardiovascular System & Vascular Biology Published on 2021-04-212022-10-31 Journal: Clinical Science (London, England : 1979) [Category] COVID-19, MERS, SARS, [키워드] ACE2 ACE2 expression ACE2 receptor acute respiratory syndrome ADAM17 addressed angiotensin II type 1 receptor blocker angiotensin-converting enzyme inhibitor candesartan Clin coronavirus COVID-19 COVID-19 pandemic COVID-19 patients Culture entry receptor enzyme humans inhibitor interfere lung tissue pathophysiological pathway Pneumocytes Protective RAS RAS inhibitor receptor reduced SARS-CoV-2 SARS-CoV-2 spike protein up-regulated [DOI] 10.1042/CS20210182 PMC 바로가기 [Article Type] Cardiovascular System & Vascular Biology
Displacement ventilation: a viable ventilation strategy for makeshift hospitals and public buildings to contain COVID-19 and other airborne diseases1004 Published on 2020-09-302022-10-28 Journal: Royal Society Open Science [Category] COVID-19, [키워드] addressed Adequate airborne disease control asymptomatic patient caused Clin COVID-19 COVID-19 outbreak disease displacement expel Guangzhou, China hospital hospital ward hospitals isolation rooms lack lockdown makeshift hospitals mechanical ventilation natural ventilation outbreak Outbreaks Patient positive reduce reported required SARS-CoV-2 virus Structure subsequent the disease treated Ventilated Ventilation [DOI] 10.1098/rsos.200680 PMC 바로가기 [Article Type] 1004
Letter of concern re: “Analysis of Covid-19 and non-Covid-19 viruses, including influenza viruses, to determine the influence of intensive preventive measures in Japan. J. Clin. Virol. 2020; 129: 104543. doi:10.1016/j.jcv.2020.104543”Article Published on 2020-09-092022-11-01 Journal: Journal of Clinical Virology [Category] Coronavirus, SARS, [키워드] Clin determine influenza viruses Intensive Japan preventive measure viruses [DOI] 10.1016/j.jcv.2020.104635 PMC 바로가기 [Article Type] Article