Clinical improvement – Communicable Diseases Research

Efficacy and safety of glucocorticoids in the treatment of COVID-19: a systematic review and meta-analysis of RCTs

Review

Published on 2024-07-132024-09-05
Journal: Clinical and experimental medicine [Category] update2024,

[키워드] Clinical improvement Corticosteroids COVID-19 Meta-analysis Mortality
[DOI] 10.1007/s10238-024-01405-0 PMC 바로가기 [Article Type] Review

Associations of nirmatrelvir-ritonavir treatment with death and clinical improvement in hospitalized patients with COVID-19 during the Omicron wave in Beijing, China: a multicentre, retrospective cohort study

Infectious Diseases

Published on 2024-02-142024-09-05
Journal: Annals of Medicine [Category] update2024,

[키워드] all-cause death Clinical improvement COVID-19 Nirmatrelvir-ritonavir off-label treatment real-world
[DOI] 10.1080/07853890.2024.2313062 PMC 바로가기 [Article Type] Infectious Diseases

Early treatment of Favipiravir in COVID-19 patients without pneumonia: a multicentre, open-labelled, randomized control study

Article

Published on 2022-12-012022-11-15
Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 치료기술, 치료제,

Does timing matter on tocilizumab administration? Clinical, analytical and radiological outcomes in COVID-19

Article

Published on 2022-11-012022-11-15
Journal: European Journal of Hospital Pharmacy [Category] SARS, 진단,

[키워드] 30-Day mortality Administered administration adverse event adverse events analysed Biomarker C-reactive protein clinical Clinical improvement cohorts of patient comparable complementary Complementary therapies coronavirus disease COVID-19 Critical Critical care decrease Efficacy epidemiologically group hospitalised Hypothesis inflammatory parameters knowledge lactate dehydrogenase medication Mortality onset of symptom outcome Patient patients with COVID-19 pharmacological treatment Pneumonia Primary outcome pulmonary medicine Quotient radiological radiological improvement radiology randomised controlled trial reductions in SaO_{2} secondary Severe COVID-19 pneumonia statistically significant difference subgroup subgroups the timing therapy Tocilizumab tocilizumab administration two group were recorded while
[DOI] 10.1136/ejhpharm-2020-002669 PMC 바로가기

Aseptic Abscess Syndrome in Rheumatoid Arthritis Patient

Article

Published on 2022-09-272022-11-15
Journal: Medicina [Category] 진단,

[키워드] abdominal pain abscess accompanied adalimumab Antibiotics Aseptic aseptic abscess syndrome Autoimmune diseases Bacteria characterized Clinical improvement Complete corticosteroid therapy COVID-19 infection disorder extension feature Fever IBD include Inflammatory Inflammatory bowel disease Inflammatory marker internal organ joints lack lesion lesions Leukocytosis liver Lungs microbe neutrophilic parasites Patient potentially life-threatening Practitioner Prednisone recognize reduction Remdesivir Rheumatoid rheumatoid arthritis sensitivity spleen Symptom syndrome systemic symptom tissue treated Treatment viruses weight loss
[DOI] 10.3390/medicina58101354 PMC 바로가기

COVID-19 Convalescent Plasma and Clinical Trials: Understanding Conflicting Outcomes

Article

Published on 2022-09-212022-11-16
Journal: Clinical microbiology reviews [Category] Fulltext, MERS, 변종,

[키워드] acute respiratory syndrome administration analyzed antibody approaches benefit case sery CCP clinical Clinical improvement clinical settings clinician Confusion convalescent convalescent plasma coronavirus COVID-19 COVID-19 pandemic criteria defined demonstrated Diagnosis disease severity dose Efficacy Emergency use authorization Epidemics EUA FDA Hospitalization include less mechanism Molecular diagnosis Mortality Neutralizing Neutralizing antibodies Neutralizing titer omicron onset of symptoms outcome Patient plasma Pneumonia polyclonal propensity score-matched randomization Randomized randomized clinical trial Randomized controlled trial RCT RCTs reductions in reported resulting SARS-CoV-2 serostatus Survivors Therapies Treatment Trial understanding variable variant Ventilation Viral neutralization tests WHO guideline
[DOI] 10.1128/cmr.00200-21 PMC 바로가기

Inhaled aviptadil for the possible treatment of COVID-19 in patients at high risk for ARDS: study protocol for a randomized, placebo-controlled, and multicenter trial

Article

Published on 2022-09-202022-11-16
Journal: Trials [Category] SARS, 변종,

[키워드] acute lung injury acute respiratory distress addition adverse effects antibody applied ARDS Aviptadil baseline Clinical improvement clinical status Concentration conducted COVID-19 COVID-19 in patient COVID-19 patient defined double-blinded Efficacy and safety Europe exclusion criteria FIVE hemodynamic instability high risk homeostasis hospital discharge Hospitalization immunomodulating IMPROVE indicate Inhaled intensive care intestinal intravenously lung lung tissue management mechanical ventilation metabolism Mortality multicenter Multicenter trial pandemic Pathways Patient patients hospitalized peptide placebo-controlled Prevent primary endpoint pro-inflammatory Prognosis Protein Public Hospital Randomized randomized trial Randomly reduction Regulation respiratory complication Risk factors SARS-CoV-2 severe disease course shown standard care stratified Study protocol suggested syndrome the SARS-CoV-2 therapeutic agent Therapies therapy Treatment unique vaccination Vaccine variants of SARS-CoV-2 Vasoactive VIP VIP. with COVID-19 World Health Organization
[DOI] 10.1186/s13063-022-06723-w PMC 바로가기

A home-based, multidisciplinary liver optimisation programme for the first 28 days after an admission for acute-on-chronic liver failure (LivR well): a study protocol for a randomised controlled trial

Article

Published on 2022-09-052022-10-05
Journal: Trials [Category] 임상,

[키워드] 1:1 28-day mortality addition Admission Admissions Analysis Appendix 1 benefit Care changes in chronic chronic condition chronic disease chronic liver disease cirrhosis clinical Clinical improvement Clinicians Cohort conducted COVID-19 COVID-19 pandemic criteria disease evaluated exploratory subgroup analysis feasibility generalisability generate global healthcare Health Health Service health team healthcare Healthcare systems heart failure hospitalisation implementation implication include Interdisciplinary health team. interim analysis Intervention intervention arm liver Liver disease Melbourne, Australia Mortality mortality risk New outcome participant Patient performed Prevalence Primary outcome Quality of life randomisation randomised randomised controlled trial RCT readmission recruit recruited recruitment reduced reducing Registered Registration registry required resource rising robust Safe secondary severity small sample size social work Study protocol suggested Treatment Trial well WHO
[DOI] 10.1186/s13063-022-06679-x PMC 바로가기 [Article Type] Article

Clinical improvement of a toddler with COVID-19 focal cerebral arteriopathy possibly due to intra-arterial nimodipine

Short communication

Published on 2022-09-012022-10-05
Journal: European journal of paediatric neurology : EJPN : [Category] COVID19(2023년), SARS, 변종, 임상,

[키워드] arteriopathy cause clinical Clinical improvement complication of COVID-19 Focal healthy child injection knowledge reported SARS-COV-2 infection stroke with COVID-19
[DOI] 10.1016/j.ejpn.2022.07.007 [Article Type] Short communication

Management of complicated acute sinusitis in the setting of concurrent COVID-19

Case report

Published on 2022-09-012022-10-05
Journal: American journal of otolaryngology [Category] 임상,