Utility of demographic and clinical signs as diagnostic predictors for leptospiral uveitis: A retrospective studyOriginal Article Published on 2024-06-082024-09-05 Journal: Indian journal of ophthalmology [Category] update2024, [키워드] clinical diagnostic rule Clinical signs diagnostic predictors leptospiral uveitis leptospirosis [DOI] 10.4103/IJO.IJO_1376_23 PMC 바로가기 [Article Type] Original Article
Pulmonary lesions following inoculation with the SARS-CoV-2 Omicron BA.1 (B.1.1.529) variant in Syrian golden hamsters시리아 골든 햄스터에서 SARS-CoV-2 Omicron BA.1(B.1.1.529) 변종 접종 후 폐 병변Article Published on 2022-12-012022-09-11 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 변종, [키워드] animals B.1.1.529 B.1.617.2 characterized Clinical signs COVID-19 disease decrease Delta Disease progression disease severity evaluate Evidence evidence of golden hamster hamster hamsters histopathological Human Immune escape Immunity Infection inoculated intrinsic Kinetics lesion Mutation omicron Omicron BA.1 pathogenicity pathological changes pathology Pneumonia pre-existing immunity progression pulmonary re-challenge. reduced SARS-CoV-2 SARS-CoV-2 variant Syrian golden hamster the SARS-CoV-2 vaccination variant viral genome viral shedding viral spread virus [DOI] 10.1080/22221751.2022.2095932 PMC 바로가기 [Article Type] Article
Prevalence of peripheral neuropathy and myopathy in patients post-COVID-19 infectionArticle Published on 2022-11-012022-11-16 Journal: International journal of rheumatic diseases [Category] SARS, 치료기술, [키워드] acute respiratory syndrome addition affecting All participant asymptomatic patient both group caused clinical examination Clinical signs Complete complications control group controls COVID-19 COVID-19 infection Department Electrophysiology Epidemic evaluate feature Gender groups healthy volunteer history Hospitalization Infection involved laboratory measure life-threatening long-lasting multiple organs Myopathy nervous system Patient patients performed Peripheral Neuropathy post-COVID-19 patient Prevalence problem recent respiratory symptom risk factor Risk factors SARS-CoV-2 serum creatine phosphokinase significant difference symptomatic without symptom [DOI] 10.1111/1756-185X.14409 PMC 바로가기
B.1.351 SARS-CoV-2 Variant Exhibits Higher Virulence but Less Viral Shedding than That of the Ancestral Strain in Young Nonhuman PrimatesArticle Published on 2022-10-262022-11-16 Journal: Microbiology Spectrum [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, [키워드] addition Alpha animal model association B.1.351 Beta caused changes in Characteristics Chinese circulating Clinical signs contribute determine distribution drugs early stage Efficacy and safety elevated exhibited IFN-γ IL-17 Infection Inflammatory Inflammatory cytokine interferon gamma interleukin 17 investigated less Lower respiratory tract lung tissue mechanisms mutated Necrosis NHP NHPs nonhuman primate pathogenesis of SARS-CoV-2 pathogenic pathogenicity pathological changes primate provide pulmonary inflammation reduced replicated Research rhesus macaque SARS-CoV-2 SARS-CoV-2 strain SARS-CoV-2 vaccine SARS-CoV-2 variant SARS-CoV-2 variants severe lung injury shedding spike-specific T-cell response strain Strains tissue TNF-α Transmission upper respiratory tract Vaccine variant variants of concern viral distribution viral shedding virulence virulent VoC VOCs were infected [DOI] 10.1128/spectrum.02263-22 PMC 바로가기
Multi-species outbreak of SARS-CoV-2 Delta variant in a zoological institution, with the detection in two new families of carnivoresArticle Published on 2022-09-012022-11-16 Journal: Transboundary and emerging diseases [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] acute respiratory syndrome Analysis carnivore Chicago Clinical signs coronavirus correlated COVID-19 delta variant distribution dose events faece host range Human human SARS-CoV-2 strains human-to-animal transmission mammalian nasal swab outbreak pandemic Procyonidae qRT-PCR SARS-CoV-2 severe acute respiratory syndrome Coronavirus Society strain Supportive treatment Test tested Vaccine Viverridae zoo zoo. [DOI] 10.1111/tbed.14662 PMC 바로가기
Prevalence of Malaria and Covid-19 in Febrile Patients in Lomé, Togo in 20202020년 토고 로메의 열성 환자에서 말라리아와 코비드-19의 유병률Article Published on 2022-09-012022-09-11 Journal: Acta parasitologica [Category] COVID19(2023년), MERS, SARS, 말라리아, 진단, 치료기술, [키워드] 95% CI Antigen Blood Clinical sign Clinical signs conducted Contamination COVID-19 cross-reactivity cross-sectional cross-sectional study detect detection diagnostic tests EDTA EDTA tube EDTA tubes febrile febrile patient Febrile patients female finger Health health facilities identify IgG IgM Immunoglobulin IQR malaria median age nasopharyngeal sample Nasopharyngeal samples participant Patient patients PCR Plasmodium positive Prevalence Rapid diagnostic test Rapid tests RDT rRT-PCR SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 antibody SARS-CoV-2 IgM serological test Serological tests significantly higher stick Togo venous venous blood was collected was performed [DOI] 10.1007/s11686-022-00586-6 PMC 바로가기 [Article Type] Article
Early Isolates of SARS-CoV-2 Result in Different Pathogenesis in the Transduced Mouse Model of COVID-19SARS-CoV-2의 초기 분리물은 COVID-19의 형질도입된 마우스 모델에서 다른 병인을 초래합니다Article Published on 2022-08-132022-09-11 Journal: Viruses [Category] SARS, 변종, [키워드] Adenovirus alveolar inflammation BALB/c mice body weight Body weight loss Clinical sign Clinical signs COVID-19 dissemination expression followed by hACE2 hACE2 receptor Histopathology in vivo Infection isolate isolates kidney liver lung Lung histopathology Lungs mice Model mouse mouse model peaking post infection provide response Result resulting SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 virus SARS-CoV-2 virus variant spleen subsequent recovery susceptible the SARS-CoV-2 virus transduced transduction undetectable Victoria viral variant Viral variants virulence virus weight loss [DOI] 10.3390/v14081769 PMC 바로가기 [Article Type] Article
Manifestation of SARS-CoV-2 Infections in Mink Related to Host-, Virus- and Farm-Associated Factors, The Netherlands 2020숙주, 바이러스 및 농장 관련 요인과 관련된 밍크의 SARS-CoV-2 감염 징후, 네덜란드 2020Article Published on 2022-08-112022-09-11 Journal: Viruses [Category] SARS, 치료기술, [키워드] acquisition age animal reservoirs animals apathy biosecurity clinical Clinical sign Clinical signs Cluster Clustering Contact containment measures contribute disease disease outbreaks epidemiological explain farm feed intake Health Human identify IMPROVE increased mortality investigated Laboratory Laboratory test males management manifestation Measures mink mink farms Mutation Netherland one health outbreak random reason Rectal swabs reduced reducing respiratory signs risk risk factor Risk factors SARS-CoV-2 Seven Sex spillover and spillback Spread Surveillance suspicion Swab Throat throat swabs Transmission transmission route virus virus detection was performed were recorded wildlife zoonose zoonoses zoonoses and reverse zoonoses. [DOI] 10.3390/v14081754 PMC 바로가기 [Article Type] Article
SARS-CoV-2 in a Mink Farm in Italy: Case Description, Molecular and Serological Diagnosis by Comparing Different Tests이탈리아 밍크 농장의 SARS-CoV-2: 사례 설명, 다양한 테스트 비교를 통한 분자 및 혈청학적 진단Case Reports Published on 2022-08-082022-09-11 Journal: Viruses [Category] SARS, 진단, 치료기술, [키워드] anti-S antibodies approach assumed Asymptomatic circulation clades clinical clinical examination Clinical sign Clinical signs collected Combination dead described description Diagnosis diagnostic test diagnostic tests farm Genome increased mortality Italian Italy mink mink farm occurred PCR PCR-positive Phylogenetic Phylogenetic analysis positive RT-PCR S protein SARS-CoV-2 SARS-CoV-2 diagnosis SARS-COV-2 infection SARS-CoV-2 sequence SARS-CoV-2 sequences sequence sera serological serology specific antibodies specific antibody Surveillance Swab swabs Test tested the S protein traceability virus was performed worker [DOI] 10.3390/v14081738 PMC 바로가기 [Article Type] Case Reports
rVSV-ΔG-SARS-CoV-2-S vaccine: repeated intramuscular (IM) toxicity, local tolerance, immunogenicity and biodistribution study in NZW rabbitsrVSV-ΔG-SARS-CoV-2-S 백신: NZW 토끼에서 반복되는 근육내(IM) 독성, 국소 내성, 면역원성 및 생체 분포 연구Article Published on 2022-08-012022-09-11 Journal: Archives of Toxicology [Category] COVID19(2023년), MERS, SARS, 비임상, 진단, 치료기술, [키워드] Administered animals antibody antibody levels Antibody titers Antigen assigned binding biodistribution biodistribution study body temperature body weight breath C-reactive protein change Clinical pathology Clinical signs clinical trial clinical trials correlated COVID-19 detection elicited evaluate Express followed by Gross High-dose high-dose group histopathological iliac lymph node immunogenicity inflammatory reaction injection intervals intramuscular intramuscularly Local local reactions Lymph node mesenteric lymph nodes Necrosis Neutralizing antibodies Neutralizing antibody titer neutralizing antibody titers New Nonclinical ophthalmology pathology Phase 2 platform Reactions repeated RNA Safe Safety SARS-CoV-2 SARS-CoV-2-S significant increase spleen stomatitis supported systemic the vaccine Tolerance Toxicity two group two groups Urinalysis vaccination Vaccine vaccine doses Vector-based vaccine vesicular stomatitis vesicular stomatitis virus Viremia VSV was performed [DOI] 10.1007/s00204-022-03302-5 PMC 바로가기 [Article Type] Article