Outcome of hospitalized patients with COVID-19 and predictors at the Buea Regional Hospital, South West region of CameroonResearch Published on 2024-04-042024-09-05 Journal: The Pan African Medical Journal [Category] update2024, [키워드] Cameroon co-morbidities COVID-19 Mortality [DOI] 10.11604/pamj.2024.47.165.34572 PMC 바로가기 [Article Type] Research
HLA-C dysregulation as a possible mechanism of immune evasion in SARS-CoV-2 and other RNA-virus infectionsArticle Published on 2022-10-172022-11-16 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] alteration Analysis antigenic Cell cells changes in co-morbidities COVID-19 COVID-19 patient COVID-19 patients decrease DNA DNA methylation dysregulation enhancer enhancer transcriptional regulation evade expression Gene Expression gene expression profile genes encoding healthy controls HLA-C Host immune evasion immune response immune system implicated Infection inhibit Intervention involved mechanism memory response Methylation modify overlap Pathogens presenting Prognosis Prognostic marker Protein respiratory infection SARS-CoV-2 shown significantly symptomatic and asymptomatic symptomatic and asymptomatic COVID-19 T-cell therapeutic target transcriptional upper airway upper airways cells. viral antigens virus [DOI] 10.3389/fimmu.2022.1011829 PMC 바로가기
Therapeutic and palliative role of a Unani herbal decoction in COVID-19 and similar respiratory viral illnesses: Phytochemical & pharmacological perspectiveReview article Published on 2022-10-012022-10-05 Journal: Journal of ethnopharmacology [Category] COVID19(2023년), SARS, 변종, 신약개발, [키워드] Administered anti-bacterial Anti-inflammatory Anti-viral articles Ayurveda caused classical co-morbidities co-morbidity Complication complications Cordia coronavirus disease-2019 COVID-19 COVID-19 incidence develop drug Effect effective Efficacy English Government of India gut microbiota healthy help Home isolation Homeopathy Influenza influenza viruses information ingredient Joshānda mechanism Medicine mild patient mitigate morbidity and mortality observation Occurrence offer organ pathological change Perspective pharmacological physiological functions phytochemical Prevent Prophylactic proportion Protective reduce Regulation Research respiratory respiratory infections respiratory tract respiratory viral respiratory viral infection respiratory viral infections searched self-care severe disease Siddha the disease therapeutic therapeutic activity therapeutic benefits Unani decoction website were excluded yoga [DOI] 10.1016/j.jep.2022.115526 [Article Type] Review article
COVID-19 in spinal cord injury patients at a veterans administration hospital: A case seriesArticle Published on 2022-09-012022-11-16 Journal: The journal of spinal cord medicine [Category] SARS, 치료기술, [키워드] administration age AIS Asymptomatic BMI case sery Chronic kidney disease chronic obstructive clinical feature Clinical findings co-morbidities Comorbidity Complete Completeness Confirmed COVID-19 infection cough COVID-19 COVID-19 pandemic Critical diagnostic disease course elevated facilitate Fever FIVE General population hospital implementation individual Infection Inflammatory marker Injury Level male Mild Patient predictor Presence presenting severe SARS-CoV-2 severity shown single center spinal cord Spinal cord injury treated Treatment unit veteran viral spread with COVID-19 [DOI] 10.1080/10790268.2020.1871254 PMC 바로가기
SARS-CoV-2 infects human cardiomyocytes promoted by inflammation and oxidative stressSARS-CoV-2는 염증과 산화 스트레스에 의해 촉진되는 인간 심근세포를 감염시킵니다Article Published on 2022-09-012022-09-12 Journal: International journal of cardiology [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] accounted acute respiratory syndrome analysed antiviral intervention Apoptosis apoptotic cardiac damage Cardiomyocytes cell damage cells change co-morbidities condition conditions COVID-19 patient Cytokine storm Donor driven by heart Heart damage heart failure infect Inflammation Inflammatory involved marker mechanism Myocardial non-infected oxidative stress Patient pro-inflammatory promote promoted protease provide Respiratory illness SARS-CoV-2 SARS-CoV-2 entry SARS-CoV-2 infected patient target tissue triggered ventricular viral entry virus entry [DOI] 10.1016/j.ijcard.2022.05.055 PMC 바로가기 [Article Type] Article
U-shaped association between abnormal serum uric acid levels and COVID-19 severity: reports from the Japan COVID-19 Task ForceResearch article Published on 2022-09-012022-10-05 Journal: International Journal of Infectious Diseases [Category] 바이오마커, 유전자 메커니즘, [키워드] addition Admission association body mass index Clinical characteristics co-morbidities Cohort COVID-19 COVID-19 severity enrolled force High serum uric acid Hyperuricemia Hypouricemia identify IMV increased risk Invasive mechanical ventilation Japan Japanese Laboratory Logistic regression analysis Low serum uric acid objective Odds ratio Older outcomes Patient Respiratory care Result serum severity significantly uric acid with COVID-19 [DOI] 10.1016/j.ijid.2022.07.014 [Article Type] Research article
Immunogenicity of BNT162b2 COVID-19 vaccine in New Zealand adults뉴질랜드 성인에서 BNT162b2 COVID-19 백신의 면역원성Article Published on 2022-08-122022-09-11 Journal: Vaccine [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] age All participant All participants analysed anti-S IgG Antibody Response baseline Beta BMI BNT162b2 BNT162b2 mRNA vaccine BNT162b2 vaccine Cellular immune response cellular immune responses co-morbidities Cohort COVID-19 COVID-19 disease COVID-19 vaccine declined Delta diabete diabetes diabetics disease dose enrichment Ethnic groups female Gender General population IgG immune response immune responses immunoassay immunogenicity in vitro International Lower Māori median age Microparticle morbidities morbidity naïve neutralise neutralising antibody neutralising response neutralising responses neutralizing capacity New obesity of BNT162b2 Older Older adults omicron other variant other variants Pacific Islander Population prospective cohort study pulmonary disease Quantitative recipient representation response risk robust SARS-CoV-2 vaccine second dose second vaccination serious COVID-19 seroconverted serum sample serum samples strain the vaccine Vaccine variant Viral viral neutralisation Wuhan [DOI] 10.1016/j.vaccine.2022.07.009 PMC 바로가기 [Article Type] Article
Prevalence of symptoms, comorbidities, fibrin amyloid microclots and platelet pathology in individuals with Long COVID/Post-Acute Sequelae of COVID-19 (PASC)COVID-19의 긴 COVID/급성 후유증(PASC)을 가진 개인의 증상, 동반질환, 섬유소 아밀로이드 미세응고 및 혈소판 병리의 유병률Article Published on 2022-08-062022-09-11 Journal: Cardiovascular Diabetology [Category] SARS, 진단, 치료기술, [키워드] accompanied acute COVID-19 African amyloid Amyloid fibrin(ogen) analysed Atypical balance blood sample Blood samples Brain capillary cardiovascular disease cholesterol Clinical studies clinical study Clinical treatment co-morbidities Comorbidities Comorbidity comparable Concentration controlled clinical studies coronavirus coronavirus 2019 disease COVID-19 COVID-19 severity determine diabetes Diabetes Mellitus Diagnostic method Diversity dyslipidaemia Early detection effective Efficacy endotheliopathy fatigue female FIBRIN Fluorescence fluorescence microscopy foci Gender Hyperactivated platelets hypertension individual inhibit joint Long Long COVID/PASC morbidities muscle pains ogen PASC pathology Patient patients Platelet platelet hyperactivation Platelets platform provide reducing registry removal reported reversal SARS-COV-2 infection scoring system Shortness of breath South Symptom Symptoms tissues Transport Treatment type 2 diabete Type 2 diabetes mellitus [DOI] 10.1186/s12933-022-01579-5 PMC 바로가기 [Article Type] Article
Ovarian granulosa cells from women with PCOS express low levels of SARS-CoV-2 receptors and co-factorsPCOS가 있는 여성의 난소 과립막 세포는 낮은 수준의 SARS-CoV-2 수용체 및 보조 인자를 발현합니다Article Published on 2022-08-012022-09-11 Journal: Archives of gynecology and obstetrics [Category] COVID19(2023년), SARS, 치료기술, [키워드] ACE2 acute respiratory syndrome acute respiratory syndrome coronavirus BSG cardiovascular disease Cell cell types co-morbidities controls coronavirus COVID-19 CTSB CTSL datasets death diabetes DPP4 Express expresse expression Factor feature global pandemic granulosa healthy help Human in vitro In vitro fertilization indicate Infection investigated IVF knowledge Lower lower expression material Microarray microarray data morbidities obesity Oocyte organ ovarian ovarian follicle Ovarian granulosa cells Ovary pandemic PCOS polycystic ovary protease receptor reproductive risk Safe SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 receptor severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 susceptibility susceptible syndrome tissue TMPRSS2 Type-2 diabetes mellitus women [DOI] 10.1007/s00404-022-06567-4 PMC 바로가기 [Article Type] Article
CMV seropositivity is a potential novel risk factor for severe COVID-19 in non-geriatric patientsCMV 혈청 양성은 비노인 환자에서 심각한 COVID-19에 대한 잠재적인 새로운 위험 요소입니다Article Published on 2022-05-252022-09-11 Journal: PLoS ONE [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료기술, [키워드] absence advanced age affected Analysis Biomarker CMV co-morbidities Cohort cohorts Comorbidities confirmation COVID-19 Critical cross-reactivity cytomegalovirus deaths detectable disease disease severity distribution finding herpes simplex herpes simplex virus higher risk Hypothesis ICU IgG individual individuals intensive care investigated Mild Mild disease moderate morbidities occur older patients Patient performed prediction Prevalence representing risk factor SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants serology Seropositivity serostatus severe COVID-19 severe disease statistical Support T cell T cells were used with mild disease [DOI] 10.1371/journal.pone.0268530 PMC 바로가기 [Article Type] Article