Demographic characteristics, clinical presentation and in-hospital outcome among patients with Covid-19 in a Nigerian tertiary hospitalOriginal Research Published on 2023-03-012024-09-05 Journal: Malawi medical journal : the journal of Medical As [Category] update2024, [키워드] Clinical features co-morbidity COVID-19 Epidemiology Mortality Nigeria [DOI] 10.4314/mmj.v35i1.8 PMC 바로가기 [Article Type] Original Research
Influence of COVID-19 pandemic on the decision making of patients in undergoing gamma knife radiosurgeryArticle Published on 2022-10-292022-11-16 Journal: European Journal of Medical Research [Category] 변종, [키워드] affected age analyses analyzed approach approval attenuate characteristic co-morbidity collected Comorbidity control group COVID-19 COVID-19 pandemic COVID-19 vaccination database decision Decision making Diagnosis Follow-up Frequency Gamma Gamma knife influence lesion lesions less MRI neurological Neurological deficit pandemic parameter Patient patients treated performance proportion Radiation Radiation dose Radiosurgery Sex status time interval treated Treatment vaccination variant Volume [DOI] 10.1186/s40001-022-00859-w PMC 바로가기
Interplay between demographic, clinical and polygenic risk factors for severe COVID-19Article Published on 2022-10-132022-11-15 Journal: International Journal of Epidemiology [Category] COVID19(2023년), SARS, 변종, 치료제, [키워드] 95% CI adjusted odds ratio Admission age antiviral response association co-morbidity conducted COVID-19 COVID-19 diagnosis Critical care death develop diagnosed with COVID-19 enrolment Epidemiology European Factor Factors General population genetic data genetic risk factor Genetic variant greater highest hospital Hospitalization identify IMPROVE individual interquartile range lowest median men morbidity obesity outcomes participant Pathway analysis Pathways Patient polygenic risk score polymorphism PRS reported risk risk factor risk prediction severe COVID-19 single-nucleotide Smokers socio-demographic UK biobank was performed [DOI] 10.1093/ije/dyac137 PMC 바로가기
Real-world effectiveness of steroids in severe COVID-19: a retrospective cohort studyArticle Published on 2022-10-052022-11-16 Journal: BMC Infectious Diseases [Category] COVID19(2023년), SARS, 변종, [키워드] age analysed association clinical co-morbidity Cohort confounder Controlled trial Coronavirus disease 2019 COVID-19 defined Dexamethasone disease Effectiveness EPR Gender hazard hospital Hydrocortisone hypoxia in-hospital mortality individual Methylprednisolone Mortality multivariable multivariate model outcome Patient positive patient Prednisolone protective effect randomised clinical trial reduce replicate replicated reported retrospective cohort study Retrospective study risk SARS-CoV-2 RNA SARS-CoV-2 variant severe COVID-19 shown steroid steroid treatment Steroids treated Treatment viral genome was measured [DOI] 10.1186/s12879-022-07750-3 PMC 바로가기
Therapeutic and palliative role of a Unani herbal decoction in COVID-19 and similar respiratory viral illnesses: Phytochemical & pharmacological perspectiveReview article Published on 2022-10-012022-10-05 Journal: Journal of ethnopharmacology [Category] COVID19(2023년), SARS, 변종, 신약개발, [키워드] Administered anti-bacterial Anti-inflammatory Anti-viral articles Ayurveda caused classical co-morbidities co-morbidity Complication complications Cordia coronavirus disease-2019 COVID-19 COVID-19 incidence develop drug Effect effective Efficacy English Government of India gut microbiota healthy help Home isolation Homeopathy Influenza influenza viruses information ingredient Joshānda mechanism Medicine mild patient mitigate morbidity and mortality observation Occurrence offer organ pathological change Perspective pharmacological physiological functions phytochemical Prevent Prophylactic proportion Protective reduce Regulation Research respiratory respiratory infections respiratory tract respiratory viral respiratory viral infection respiratory viral infections searched self-care severe disease Siddha the disease therapeutic therapeutic activity therapeutic benefits Unani decoction website were excluded yoga [DOI] 10.1016/j.jep.2022.115526 [Article Type] Review article
Evaluating the efficacy and safety of a novel prophylactic nasal spray in the prevention of SARS-CoV-2 infection: A multi-centre, double blind, placebo-controlled, randomised trialRandomized Controlled Trial Published on 2022-10-012022-10-04 Journal: Journal of Clinical Virology [Category] COVID19(2023년), SARS, 임상, [키워드] absence Administered analysed Anti-spike clinical clinical symptom clinical trial co-morbidity Community Course COVID-19 COVID-19 pandemic double blind Effect Efficacy and safety eligibility criteria evaluate Evaluating healthcare Immunoglobulin Infection nasal offer participant Placebo placebo-controlled placebo-controlled trial positive primary end point Prophylactic Prophylaxis random randomised Randomised trial Randomized reduced Result Safe SARS-CoV-2 SARS-COV-2 infection significantly subject tested the primary endpoint the spike protein Treatment vaccination [DOI] 10.1016/j.jcv.2022.105248 PMC 바로가기 [Article Type] Randomized Controlled Trial
Outcomes following SARS-CoV-2 infection in patients with primary and secondary immunodeficiency in the UKArticle Published on 2022-09-292022-11-15 Journal: Clinical and experimental immunology [Category] SARS, 진단, [키워드] access age anti-SARS-CoV-2 baseline co-morbidity Cohort Combination convalescent plasma COVID-19 COVID-19 treatment CVID demonstrated Dexamethasone died Fatality rate General population high risk hospital Hypogammaglobulinemia IFR immunodeficiency inborn errors of immunity increased the risk Increasing individual Infection Lymphocyte count lymphopenia monotherapy Mortality network outcome overall mortality Patient PID Primary immunodeficiencies receiving REGN-CoV2 Remdesivir reported risk factor SARS-CoV-2 SARS-COV-2 infection secondary immunodeficiencies. therapeutic Tocilizumab Treatment United Kingdom [DOI] 10.1093/cei/uxac008 PMC 바로가기
Case report: Understanding the impact of persistent tissue-localization of SARS-CoV-2 on immune response activity via spatial transcriptomic analysis of two cancer patients with COVID-19 co-morbidityArticle Published on 2022-09-122022-11-15 Journal: Frontiers in Immunology [Category] SARS, 유전자 메커니즘, 진단, [키워드] acute respiratory syndrome addition Analysis association B cell cancer patient Cancer patients cancer treatment Case report co-morbidity Colorectal cancer Comorbidity coronavirus correlation COVID-19 demonstrated Effect evaluated Evidence Ex vivo examined exclusion experiment HCC Hepatocellular carcinoma heterogeneity highest Immune checkpoint blockade immune dysfunction immune response immune responses Immunity immunohistochemistry immunological effect Immunological memory Immunotherapy Inflammation intra-tumor heterogeneity long-term immune memory lymphocyte Macrophage infiltration memory B cell modulate multiplex nasopharyngeal swab test Patient persistence Population positive predicted profile Reinfection response SARS-CoV-2 significantly Single-cell RNA sequencing spatial localization spatial transcriptomics Support T cell T cell dysfunction tissue tissue-localized immunity. tissues transcriptomic transcriptomic analysis Tumor tumor microenvironment understanding virus while with COVID-19 [DOI] 10.3389/fimmu.2022.978760 PMC 바로가기
Trends in COVID-19 hospital outcomes in England before and after vaccine introduction, a cohort study Research Published on 2022-08-172022-10-05 Journal: Nature Communications [Category] SARS, 치료법, [키워드] 95% confidence interval Admission changed co-morbidity cohort study COVID-19 COVID-19 cases demographic factor discharge England estimate fatality hospital hospital resources hospitalised individual morbidity and mortality Mortality outcome outcomes pandemic Prognosis ranged reducing risk Symptom trend vaccination Vaccine vaccine dose with COVID-19 [DOI] 10.1038/s41467-022-32458-y [Article Type] Research
The usefulness of D-dimer as a predictive marker for mortality in patients with COVID-19 hospitalized during the first wave in Italy이탈리아의 첫 번째 물결 동안 입원한 COVID-19 환자의 사망률에 대한 예측 마커로서 D-dimer의 유용성Article Published on 2022-07-222022-09-11 Journal: PLoS ONE [Category] COVID19(2023년), MERS, SARS, 바이오마커, [키워드] addition age Analysis assist C-index Clinical characteristics co-morbidity cohort study competing coronavirus disease Coronavirus disease 2019 COVID-19 cumulative cumulative incidence D-dimer death diagnosed with COVID-19 died dimer First wave global health Health healthcare hospital Hospital mortality Hospitalized hospitalized patient hospitalized patients identification in-hospital mortality incidence Italy lead lombardy majority marker medical staff Model moderate morbidities Mortality occurred outcome Patient patient records patients patients with COVID-19 performed Predictive Predictive value predictor primary endpoint Real-time PCR resources risk Sex statistical analyses study population survival Treatment was obtained [DOI] 10.1371/journal.pone.0264106 PMC 바로가기 [Article Type] Article