Hepatitis B virus (HBV) codon adapts well to the gene expression profile of liver cancer: an evolutionary explanation for HBV’s oncogenic roleArticle Published on 2022-11-012022-11-16 Journal: Journal of microbiology (Seoul, Korea) [Category] B형 간염, COVID19(2023년), SARS, 유전자 메커니즘, [키워드] addition Arm association CAI calculated cells codon adaptation index codon adaptation index (CAI) codon usage correlation evolutionary arms race expressed gene gene expression profile HAV HBV HCC HCV Hepatitis hepatitis viruses Hepatocellular carcinoma hepatocellular carcinoma (HCC) highest Host human genes human tissues initial liver liver cell Lungs oncogenesis oncogenic Perspective relative synonymous codon usage (RSCU). Replication RNA SARS-CoV-2 synonymous translation tRNA Viral proteins Viral RNA virus viruses [DOI] 10.1007/s12275-022-2371-x PMC 바로가기
Analysis of SARS-CoV-2 synonymous codon usage evolution throughout the COVID-19 pandemicCOVID-19 전염병 전반에 걸친 SARS-CoV-2 동의어 코돈 사용 진화 분석Article Published on 2022-03-012022-09-11 Journal: Virology [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] accompanied Analysis antagonistic Betacoronavirus bioinformatic analysis codon codon adaptation index codon usage Codon usage bias Codons collected Complete coronavirus COVID-19 COVID-19 pandemic decrease effective Evolution Evolution of SARS-CoV-2 Genome human host humans infect less life-threatening pathogenic Perspective respiratory pathologies SARS-CoV-2 SARS-CoV-2 evolution synonymous [DOI] 10.1016/j.virol.2022.01.011 PMC 바로가기 [Article Type] Article
Evolutionary perspectives and adaptation dynamics of human seasonal influenza viruses from 2009 to 2019: An insight from codon usageArticle Published on 2021-12-012023-06-23 Journal: Infection, genetics and evolution : journal of mol [Category] 신종인플루엔자, [키워드] codon adaptation index codon usage CpG dinucleotide Evolutionary analysis host adaptation seasonal influenza viruses [DOI] 10.1016/j.meegid.2021.105067
Base Composition and Host Adaptation of the SARS-CoV-2: Insight From the Codon Usage PerspectiveMicrobiology Published on 2021-04-062022-10-31 Journal: Frontiers in Microbiology [Category] COVID-19, [키워드] acute respiratory syndrome adaptation adaptive Analysis avoidance base base composition Clinical severity coding sequences codon codon adaptation index codon pair usage codon usage complex interplay coronavirus CpG dinucleotide event Factor gene product Host host adaptation hosts human host human immune response human populations information insight MERS Middle East multivariate natural selection progression raised Research robust SARS-CoV SARS-CoV-2 statistical analysis syndrome Transmission dynamics Usage Vaccine viral isolate virus [DOI] 10.3389/fmicb.2021.548275 PMC 바로가기 [Article Type] Microbiology
Reverse vaccinology approach towards the in-silico multiepitope vaccine development against SARS-CoV-2SARS-CoV-2에 대한 in-silico 다중 에피토프 백신 개발을 위한 역백신학 접근법Research Article Published on 2021-01-232022-09-11 Journal: F1000Research [Category] 치료법, [키워드] acute respiratory syndrome adjuvant allergen allergenicity Antigen antigenicity approach B cell epitope B cell epitopes binding binding affinity C terminal CAI calculated caused codon adaptation index complex Corona virus coronavirus disease Coronavirus disease 2019 COVID-19 cytotoxic Cytotoxic T cell disease docked docking E. coli effective Epitopes experimental validation expression fatal COVID-19 GC content helper T cell human body immunization immunoinformatics in-silico membrane MHC molecular dynamics Molecular dynamics simulation molecular dynamics simulations multiepitope multiepitope based vaccine multiepitope vaccine Nidovirales nucleocapsid online tool pandemic pandemic coronavirus polyprotein predict predicted receptor reduction respiratory Result RMSD SARS-CoV-2 sequence Simulations spike Spread suggested T cell T cell epitopes the binding affinity tlr-3 Toxicity Vaccine vaccine candidate Vaccine development were used [DOI] 10.12688/f1000research.36371.1 PMC 바로가기 [Article Type] Research Article
Evolution of Transmissible Gastroenteritis Virus (TGEV): A Codon Usage PerspectiveArticle Published on 2020-10-242022-10-29 Journal: International Journal of Molecular Sciences [Category] Coronavirus, [키워드] adaptive addition Analysis Bayesian inference CAI coding sequence codon codon adaptation index codon usage Codon usage bias comprehensive analysis contribute coronavirus CpG current diarrhea dinucleotide dominant driving effective Evolution Genome Genotype high mortality indicated likelihood moderate Mutation mutation pressure natural selection nucleotide nucleotides parity Phylogenetic analysis Phylogeny principal component analysis rule selection pressure similarity subtype suggested synonymous TGEV transmissible gastroenteritis virus Usage was performed [DOI] 10.3390/ijms21217898 PMC 바로가기 [Article Type] Article
Analysis of codon usage of severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) and its adaptability in dogArticle Published on 2020-08-072022-11-01 Journal: Virus research [Category] COVID-19, MERS, SARS, [키워드] acute respiratory syndrome Analysis codon codon adaptation index Codon Bias codon usage Corona virus dog ENhance Evolution Factor Gene Expression Host host adaptation human SARS-CoV-2 indicated involved knowledge life-threatening molecular Mutation natural selection neutrality nucleotide pandemic parity Regulation SARS-CoV-2 SARS-CoV-2 genome selection pressure synonymous virus [DOI] 10.1016/j.virusres.2020.198113 PMC 바로가기 [Article Type] Article
Recombinant production of active Streptococcus pneumoniae CysE in E. coli facilitated by codon optimized BL21(DE3)-RIL and detergentarticle Published on 2019-12-312024-09-01 Journal: Preparative Biochemistry & Biotechnology [Category] 폐렴구균 감염증, [키워드] BL21(DE3)-RIL codon adaptation index CysE or SAT expression purification Triton X-100 [Article Type] article
The evolution of codon usage in structural and non-structural viral genes: The case of Avian coronavirus and its natural host Gallus gallusArticle Published on 2013-09-302022-11-01 Journal: Virus research [Category] Coronavirus, [키워드] Avian coronavirus Gallus gallus 100% conserved Alpha Amino acid CAI cellular coded codon codon adaptation index codon usage compared coronavirus different driving effective Evolution GC Gene Genes Genetic glycoprotein Host host gene immune intestinal kidney less Lineage lung molecular molecular basis Mutation natural selection non-structural proteins nucleocapsid oviduct Papain-like protease predicted Protein protein A relative Replication respiratory tract significantly spike spike gene subunit synonymous Topology viral spike virus Virus–host Vitamin D receptor was measured were used [DOI] 10.1016/j.virusres.2013.09.033 PMC 바로가기 [Article Type] Article