Structural insights revealed by crystal structure of B38-CAP, an isoenzyme of carboxypeptidase ACE2, the receptor of SARS-CoV-2SARS-CoV-2의 수용체인 카르복시펩티다제 ACE2의 동종효소인 B38-CAP의 결정 구조로 밝혀진 구조적 통찰력Article Published on 2022-05-282022-09-11 Journal: Biochemical and Biophysical Research Communication [Category] COVID19(2023년), SARS, 변종, [키워드] ACE2 ACE2 carboxypeptidase acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 anti-SARS-CoV-2 B38-CAP carboxypeptidase catalysis catalytic coincidence complex interplay conformational flexibility coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 crystal structure dimeric domain drugs enzyme feature Host Isoenzyme problem provide provided RAS receptor Renin renin-angiotensin system sACE2 SARS-CoV-2 SARS-CoV-2 variants severe acute respiratory syndrome Coronavirus specificity Structural analysis Treatment treatment of COVID-19 triggered variety weakened worldwide pandemic worsened [DOI] 10.1016/j.bbrc.2022.03.077 PMC 바로가기 [Article Type] Article
Coincidence of Sarcoidosis and a COVID-19 vaccine-associated hypermetabolic lymphadenopathy in a patient with a history of invasive breast cancer: A case reportCase report Published on 2022-05-012022-10-05 Journal: International Journal of Surgery Case Reports [Category] 진단, [키워드] adverse event BHLbilateral hilar lymphadenopathy bilateral hilar lymphadenopathy Breast cancer Cancer Case report clinical coincidence Computed tomography Confusion COVID 19 COVID-19 diagnostic EBUS-TBNAendobronchial ultrasound-guided trans-bronchial needle aspiration endobronchial ultrasound-guided trans-bronchial needle aspiration FDG Fluorine-18 follow-up study granuloma injection invasive Lymph node malignancy multinucleated giant cell Occurrence Patient performed postoperative Region regions sarcoidosis specimen subclavicular Thyroid tomography vaccination vaccine-associated hyper metabolic lymphadenopathy VAHLvaccine-associated hyper metabolic lymphadenopathy [DOI] 10.1016/j.ijscr.2022.107098 [Article Type] Case report
Antigenic evolution will lead to new SARS-CoV-2 variants with unpredictable severity항원 진화는 예측할 수 없는 심각성을 가진 새로운 SARS-CoV-2 변이체로 이어질 것입니다Article Published on 2022-05-012022-09-11 Journal: Nature reviews. Microbiology [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] antigenic evolution coincidence Evolution Immunity milder infection new SARS-CoV-2 omicron Omicron variant pandemic population immunity raised severity variant weakening [DOI] 10.1038/s41579-022-00722-z PMC 바로가기 [Article Type] Article
RNA-RNA interactions between SARS-CoV-2 and host benefit viral development and evolution during COVID-19 infectionSARS-CoV-2와 숙주 사이의 RNA-RNA 상호 작용은 COVID-19 감염 동안 바이러스 발달 및 진화에 도움이 됩니다Article Published on 2022-01-172022-09-11 Journal: Briefings in Bioinformatics [Category] SARS, 변종, [키워드] Absorption addition approach benefit coincidence collected COVID-19 COVID-19 infection dataset Diseases Evolution FIVE five group five groups Genes Genome genomic genomic RNA Host host cells host immune system host miRNA IL6R immune immune response immune system immune-related gene immune-related genes infect Infectious diseases Interaction interferon interleukin miRNA miRNAs mutant strain Pathogenesis pathogenicity pathway Pathways Perspective PPI predicted protein-protein interaction regulate reported RNA-RNA interaction RNA–RNA interaction SARS-CoV-2 SARS-CoV-2 genome SARS-COV-2 infection signaling pathway signaling pathways significantly survival target targets the interferon the SARS-CoV-2 genome [DOI] 10.1093/bib/bbab397 PMC 바로가기 [Article Type] Article
Occurrence of Guillain-Barre Syndrome During the Initial Symptomatic Phase of COVID-19 Disease: Coincidence or Consequence?Internal Medicine Published on 2021-11-172022-10-31 Journal: Cureus [Category] COVID-19, [키워드] Characteristics coincidence coronavirus COVID-19 Dysphagia Guillain Barre syndrome Guillain-barrè syndrome human immunoglobulin induce infected with SARS-CoV-2 Infection Inflammatory intravenous manifested molecular Multiple neurotropic neurotropic virus Patient phase shown Treatment viral infections viral mimicry virus [DOI] 10.7759/cureus.19655 PMC 바로가기 [Article Type] Internal Medicine
An unusual case of acute cholestatic hepatitis after m-RNABNT162b2 (Comirnaty) SARS-CoV-2 vaccine: Coincidence, autoimmunity or drug-related liver injurym-RNABNT162b2(Comirnaty) SARS-CoV-2 백신 후 급성 담즙정체성 간염의 드문 사례: 우연, 자가면역 또는 약물 관련 간 손상Comment Published on 2021-11-012022-09-11 Journal: Journal of hepatology [Category] MERS, SARS, 치료제, [키워드] Autoimmunity coincidence Hepatitis Liver injury SARS-CoV-2 [DOI] 10.1016/j.jhep.2021.07.005 PMC 바로가기 [Article Type] Comment
Bilateral Thalamic Stroke: A Case of COVID-19 Vaccine-Induced Immune Thrombotic Thrombocytopenia (VITT) or a Coincidence Due to Underlying Risk Factors?Preventive Medicine Published on 2021-10-222022-10-31 Journal: Cureus [Category] COVID-19, [키워드] Abnormalities adenovirus-based Bilateral bilateral thalamic disease clinically Coagulation coincidence coronavirus disease COVID 19 COVID-19 Diagnosis Efficacy FIVE heparin induced thrombocytopenia (hit) immune Immune-mediated Laboratory testing potentially life-threatening Side effect thrombocytopenia thrombosis thrombotic vaccination Vaccine vaccine preventable diseases vaccine-induced thrombotic thrombocytopenia (VITT) [DOI] 10.7759/cureus.18977 PMC 바로가기 [Article Type] Preventive Medicine
Nonarteritic Anterior Ischemic Optic Neuropathy following COVID-19 Vaccination: Consequence or CoincidenceCase Report Published on 2021-10-142022-10-31 Journal: Case Reports in Ophthalmological Medicine [Category] COVID-19, [키워드] Anterior biological plausibility Case report coincidence Complete complications consequence COVID-19 COVID-19 vaccination COVID-19 vaccine Diagnosis examination eyes first dose follow-up period Immune-mediated Inflammatory Ischemic ischemic optic neuropathy Neuropathy Optic optic disc swelling Patient Pfizer-BioNTech pupillary receiving the timing Treatment vaccination visual acuity Visual field defect with COVID-19 [DOI] 10.1155/2021/5126254 PMC 바로가기 [Article Type] Case Report
COVID-19 in Patients with Active TuberculosisCase Report Published on 2021-09-262022-10-31 Journal: Diagnostics [Category] COVID-19, [키워드] Analysis Asymptomatic Care carried coincidence Coinfection Comorbidities complex Course COVID-19 diagnosed died Diseases DNA epidemiological global pandemic high-flow oxygen therapy hospitalisation Hospitalization Infection infection with SARS-CoV-2 isolate mechanical ventilation Mild molecular Mycobacterium tuberculosis observation outbreak pandemic Patient Poland profile renal Respiratory failure SARS-CoV-2 SARS-COV-2 infection Symptom the patient the SARS-CoV-2 therapeutic Transmission Tuberculosis with HIV [DOI] 10.3390/diagnostics11101768 PMC 바로가기 [Article Type] Case Report
Dysregulated Interferon Response Underlying Severe COVID-19심각한 COVID-19의 기저에 있는 조절되지 않은 인터페론 반응Review Published on 2020-12-132022-09-10 Journal: Viruses [Category] MERS, SARS, 유전자 메커니즘, 치료제, [키워드] addition administration Antiviral Autoimmunity autonomous autoreactive antibodies autoreactive antibody coincidence Comorbidity COVID-19 COVID-19 pathogenesis COVID-19 pneumonia COVID-19 progression Critical determine dysregulation early stage elicit explained Genetic high correlation IFN IFN response IFNs immune immune interferons immunopathy Inborn individual Innate interferon interferon signaling interferons life-threatening loci males mechanisms Patient Pneumonia Prevent Prophylactic recent response restrict SARS-CoV-2 SARS-CoV-2 infections severe COVID-19 severe COVID-19 patient significantly situation spatiotemporal Therapies type I type I and III IFNs virus infection worsened [DOI] 10.3390/v12121433 PMC 바로가기 [Article Type] Review