Increased Number of Colorectal Interval Cancers in Lynch Syndrome after the SARS-CoV-2 Pandemic: A Survey-Based StudyArticle Published on 2023-01-012023-07-08 Journal: Digestive diseases (Basel, Switzerland) [Category] COVID19(2023년), [키워드] Colorectal cancer COVID-19 Hereditary surveillance. [DOI] 10.1159/000524393 PMC 바로가기
Identification of the effects of COVID-19 on patients with pulmonary fibrosis and lung cancer: a bioinformatics analysis and literature reviewArticle Published on 2022-09-262022-11-15 Journal: Scientific Reports [Category] SARS, 바이오마커, [키워드] applied approach bioinformatics Bioinformatics analysis Biomarker Cancer Colorectal cancer complications of COVID-19 core gene Coronavirus disease 2019 COVID-19 COVID-19 complication DEGs Diseases drug drug candidates Effect effective feature Health highest identification identify idiopathic IPF literature review lung lung cancer Lung fibrosis Metastasis molecular morbidity and mortality Mortality pathway Patient patients positive pulmonary fibrosis reducing risk risk factor significantly Spread Systems biology the epidemic the SARS-CoV-2 virus Transcriptome treating COVID-19 Treatment [DOI] 10.1038/s41598-022-20040-x PMC 바로가기
Case report: Understanding the impact of persistent tissue-localization of SARS-CoV-2 on immune response activity via spatial transcriptomic analysis of two cancer patients with COVID-19 co-morbidityArticle Published on 2022-09-122022-11-15 Journal: Frontiers in Immunology [Category] SARS, 유전자 메커니즘, 진단, [키워드] acute respiratory syndrome addition Analysis association B cell cancer patient Cancer patients cancer treatment Case report co-morbidity Colorectal cancer Comorbidity coronavirus correlation COVID-19 demonstrated Effect evaluated Evidence Ex vivo examined exclusion experiment HCC Hepatocellular carcinoma heterogeneity highest Immune checkpoint blockade immune dysfunction immune response immune responses Immunity immunohistochemistry immunological effect Immunological memory Immunotherapy Inflammation intra-tumor heterogeneity long-term immune memory lymphocyte Macrophage infiltration memory B cell modulate multiplex nasopharyngeal swab test Patient persistence Population positive predicted profile Reinfection response SARS-CoV-2 significantly Single-cell RNA sequencing spatial localization spatial transcriptomics Support T cell T cell dysfunction tissue tissue-localized immunity. tissues transcriptomic transcriptomic analysis Tumor tumor microenvironment understanding virus while with COVID-19 [DOI] 10.3389/fimmu.2022.978760 PMC 바로가기
Impact of the COVID-19 Pandemic on Fecal Immunochemical Testing, Colonoscopy Services, and Colorectal Neoplasia Detection in a Large United States Community-based PopulationResearch article Published on 2022-09-012022-10-05 Journal: Gastroenterology [Category] 진단, 치료기술, [키워드] affected age Cancer Care changes in Colonoscopy Colorectal Colorectal cancer COVID-19 COVID-19 pandemic declined detection diagnosed diagnostic exceeded fecal fit Health help immunochemical Impact increase in investigated National neoplasia pandemic Patient performed Population positive Positive test reached reduction in Result resulting retrospective cohort study Screening Testing United State Volume [DOI] 10.1053/j.gastro.2022.05.014 [Article Type] Research article
Impact of the COVID-19 Pandemic on Colorectal Cancer Screening: a Systematic ReviewArticle Published on 2022-09-012022-11-16 Journal: Journal of gastrointestinal cancer [Category] SARS, 치료기술, [키워드] Abstract activity article Cancer Care Colorectal Colorectal cancer Combination compensating country COVID-19 COVID-19 crisis COVID-19 pandemic declining decrease disease duplicates effective intervention eligible fit global pandemic Health hospital immunochemical Impact Infection investigated lack less maintain Mortality performed prevalence of COVID-19 prevalent reduce reduction in resource respiratory review Screening selected Surveillance systematic review. Web of Science were used WHO World Health Organization [DOI] 10.1007/s12029-021-00679-x PMC 바로가기
Individualized, heterologous chimpanzee adenovirus and self-amplifying mRNA neoantigen vaccine for advanced metastatic solid tumors: phase 1 trial interim results Research Published on 2022-08-152022-10-05 Journal: Nature Medicine [Category] 변종, 유전자 메커니즘, 임상, 치료법, [키워드] Adenovirus adverse event analyses analysis benefit Biomarker CD8 T cell circulating Colorectal cancer Combination CPI diarrhea disease DNA dose Endpoint fatigue feasibility feasible Heterologous immune inhibitor injection site pain Ipilimumab limit long-lasting mRNA Musculoskeletal nivolumab Patient phase 1 trial primary endpoint Pyrexia randomized studies reactivity regimen responses Safe Safety secondary solid tumor statistical survival therapy Tolerability toxicities transaminase translational Tumor vaccination Vaccine viral particle were assessed [DOI] 10.1038/s41591-022-01937-6 [Article Type] Research
Impact of the SARS-CoV-2 pandemic on female breast, colorectal and non-small cell lung cancer incidence, stage and healthcare pathway to diagnosis during 2020 in Wales, UK, using a national cancer clinical record systemArticle Published on 2022-08-012022-11-16 Journal: British Journal of Cancer [Category] COVID19(2023년), SARS, 치료기술, [키워드] Annual Breast cancer Cancer cancers Cell Colorectal Colorectal cancer COVID-19 pandemic declined decrease diagnose diagnosed Diagnosis female Health Service Health services healthcare Hospital admission Impact impacted impacts incidence incidence rate lung lung cancer mitigate National outcome pandemic pathway Poisson regressions population level response Stage stage I Surveillance the SARS-CoV-2 [DOI] 10.1038/s41416-022-01830-6 PMC 바로가기
Colon cancer treatment in Sweden during the COVID-19 pandemic: A nationwide register-based studyObservational Study Published on 2022-08-012022-10-05 Journal: Colorectal disease : the official journal of the A [Category] 임상, [키워드] 30-Day mortality adverse effect Cancer cancer treatment Chemotherapy Colon cancer Colorectal Colorectal cancer Colorectal surgery complications COVID-19 COVID-19 pandemic diagnose diagnosed Diagnosis Elective surgery no difference no increase observé Ostomy outcome pandemic Patient proportion reduced registry surgery pandemic. surgical Swedish time treat treated Treatment [DOI] 10.1111/codi.16129 PMC 바로가기 [Article Type] Observational Study
357 Skin cancer treatment delays during the COVID-19 pandemicConference abstract Published on 2022-08-012022-10-30 Journal: The Journal of investigative dermatology [Category] Coronavirus, 치료법, [키워드] adverse outcomes age analyzed average Bladder cancer Brain Breast cancer calculated Cancer cancer treatment cancer type Care Colon cancer Colorectal cancer coronavirus COVID-19 pandemic Frequency had more Health IBM information interview investigated leukemia likelihood lung cancer Melanoma Metastasis Mortality multivariate observation Odds ratio P-value Pancreatic cancer pandemic Patient presenting provide respondent significantly more skin cancer SPSS statistical statistically significant study cohort survey Treatment [DOI] 10.1016/j.jid.2022.05.366 [Article Type] Conference abstract
Circulating tumor DNA to guide rechallenge with panitumumab in metastatic colorectal cancer: the phase 2 CHRONOS trial Research Published on 2022-08-012022-10-05 Journal: Nature Medicine [Category] 바이오마커, 변종, 임상, [키워드] antibodies approved biopsy blockade Blood BRAF carried circulating clinical trial Colorectal cancer disease DNA Efficacy EGFR eight Endpoint enrolled EudraCT growth factor monoclonal antibody mutant alleles Mutation Open-label Patient patients primary endpoint randomized trial RAS receptor regimen responses restrict secondary single-arm phase 2 Standard-of-care subsequent survival therapy Tolerability Treatment Trial Tumor were excluded wild-type Withdrawal [DOI] 10.1038/s41591-022-01886-0 [Article Type] Research