Comparative miRNA transcriptomics of macaques and mice reveals MYOC is an inhibitor for Cryptococcus neoformans invasion into the brain원숭이와 생쥐의 비교 miRNA 전사체는 MYOC가 뇌로의 크립토코커스 네오포르만스 침입에 대한 억제제임을 보여줍니다Article Published on 2022-12-012022-09-11 Journal: Emerging Microbes & Infections [Category] 유전자 메커니즘, [키워드] AIDS Brain brain dissemination brains C. neoforman C. neoformans caused Central nervous system centric clinical samples clinically CNS Comparative Cryptococcal meningoencephalitis cryptococcosis Cryptococcus neoforman Cryptococcus neoformans cytoskeleton dissemination enhancer facilitate fungal Fungal infection help HIV/AIDS HIV/AIDS patient HIV/AIDS patients host-pathogen interactions hosts human pathogen Immune cell immune cells individuals Infection inhibitor inhibitors Invasion macaque Macrophage mechanism meningoencephalitis mice miRNA miRNA transcriptome. MYOC myocilin Pathogenic microorganisms pathway Patient patients with COVID-19 performed Prevalence regulated response reveal Transcriptome transcriptomics Trojan horse [DOI] 10.1080/22221751.2022.2081619 PMC 바로가기 [Article Type] Article
Comparative global B cell receptor repertoire difference induced by SARS-CoV-2 infection or vaccination via single-cell V(D)J sequencingSARS-CoV-2 감염 또는 단일 세포 V(D)J 시퀀싱을 통한 백신 접종에 의해 유도된 비교 글로벌 B 세포 수용체 레퍼토리 차이Article Published on 2022-12-012022-09-12 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 진단, [키워드] antibody B cell BBIBP-CorV BCR BCR repertoire change Comparative COVID-19 COVID-19 recovered patient dynamic FIVE group groups Guidance healthy healthy donor humoral immune response IGHV3-23 IGHV3-33 inactivated Inactivated vaccine Infection performed Precision proportion receptor SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 spike protein SARS-CoV-2 vaccination SARS-CoV-2 vaccine Sequencing single-cell Single-cell RNA sequencing subject subjects the SARS-CoV-2 treated vaccination Vaccine [DOI] 10.1080/22221751.2022.2105261 PMC 바로가기 [Article Type] Article
A global epidemiological analysis of COVID-19 vaccine types and clinical outcomesArticle Published on 2022-11-012022-11-16 Journal: International Journal of Infectious Diseases [Category] SARS, 변종, [키워드] adenovirus vaccine Adenovirus-vectored vaccine adjust age aggregate Analysis analyzed Clinical outcome Comparative comparative effectiveness confounding factors correlation country Coverage COVID-19 COVID-19 vaccine death distribution dominant Effectiveness eligible epidemiological evaluate inactivated Inactivated virus vaccine longitudinal analysis Messenger RNA mixed-effects modeling mRNA mRNA vaccine Nonpharmaceutical interventions P-value performed Population public health repeated measure SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants significantly higher significantly lower vaccination Vaccine Virological virus [DOI] 10.1016/j.ijid.2022.09.014 PMC 바로가기
A precise review on NAATs-based diagnostic assays for COVID-19: A motion in fast POC molecular testsArticle Published on 2022-11-012022-11-15 Journal: European Journal of Clinical Investigation [Category] SARS, 치료기술, [키워드] addressed advance approved assist authorization Care Comparative coronavirus disease COVID-19 diagnostic Diagnostic method disease Emergency expand false-negative global pandemic Health limitation mitigate molecular molecular diagnostic assays molecular test NAAT New nucleic acid amplification nucleic acid amplification techniques parameter platform POC POC testing point-of-care point-of-care testing polymerase chain RT-qPCR SARS-CoV-2 Sensitivity and specificity suggested [DOI] 10.1111/eci.13853 PMC 바로가기
Comparative study of the usefulness of risk score assessment in the early stages of COVID-19 affected pregnancies: Omicron variant versus previous variantsArticle Published on 2022-11-012022-11-16 Journal: The journal of obstetrics and gynaecology research [Category] SARS, 변종, 치료기술, [키워드] affected age Blood C-reactive protein Comparative Course COVID-19 D-dimer level Delta Deterioration disease disease onset early stage Epidemic evaluate examination findings Frequency group groups less no significant difference not significantly different omicron Omicron variant parameter Patient Platelet Pneumonia Pregnancy pregnant Prognosis risk risk scoring significantly lower two group utility variant variant of concern variants was increased worsening [DOI] 10.1111/jog.15387 PMC 바로가기
Comparative epidemiology of five waves of COVID-19 in Mexico, March 2020-August 2022Article Published on 2022-10-312022-11-16 Journal: BMC Infectious Diseases [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] 95% CI age analyzed Antigen association average calculated Care case fatality rates Comorbidities Comparative confirmed case confirmed cases COVID-19 COVID-19 case Critical death declined decrease Demographic factors Epidemic epidemic wave epidemiological Epidemiology estimates Factors Fatality rate FIVE Gender Health highest hospital Hospital admission Hospitalization hospitalizations Hospitalized In-hospital In-hospital death in-hospital mortality incidence increase in individual Intubated intubation intubations laboratory-confirmed male Metrics notable omicron pandemic Patient patients with comorbidities recorded reduction in Regression model risk SARS-CoV-2 second wave security severe disease severity subsequent Surveillance symptoms onset System vaccination variant were recorded [DOI] 10.1186/s12879-022-07800-w PMC 바로가기
Effectiveness, Policy, and User Acceptance of COVID-19 Contact-Tracing Apps in the Post-COVID-19 Pandemic Era: Experience and Comparative StudyArticle Published on 2022-10-272022-11-16 Journal: JMIR Public Health and Surveillance [Category] 변종, 치료기술, [키워드] acceptance Accuracy addition Bluetooth collected Comparative Contact Contact tracing contact-tracing app country COVID-19 COVID-19 infections CTA CTAs detection rate digital contact tracing Effectiveness example experience Google Google Scholar Guidance had no individual Infection information investigated knowledge lack mobile phone National pandemic era Policy Prevent problem problems provided reduce reducing second selected separated significantly subsequent Transmission user variants variety virus propagation website [DOI] 10.2196/40233 PMC 바로가기
Comparative Assessment of Severe Acute Respiratory Syndrome Coronavirus 2 Variants in the Ferret ModelArticle Published on 2022-10-262022-11-15 Journal: mBio [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] acute respiratory syndrome Airborne transmission Analysis assessment Beta changes Comparative Contact coronavirus coronavirus 2 COVID-19 Critical Delta disease evaluate ferret ferrets genomic variant Heterologous highest histopathological homologous homologous or heterologous Human in vivo infection with SARS-CoV-2 inoculated lineages lowest Mild Model offered pandemic Particle pathogenicity provided Reinfection replicated Replication replication kinetics respiratory respiratory tract risk RNA SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 strains SARS-CoV-2 variant Spread Strains Surveillance the spike protein the United State Transmissibility Transmission transmitted upper respiratory tract USA-WA1/2020 variant variants virulence virus virus infection virus load WA1 while [DOI] 10.1128/mbio.02421-22 PMC 바로가기
Comparative effectiveness of neutralising monoclonal antibodies in high risk COVID-19 patients: a Bayesian network meta-analysisArticle Published on 2022-10-202022-11-15 Journal: Scientific Reports [Category] COVID19(2023년), meta-analysis, SARS, 변종, 진단, [키워드] absolute reduction article baseline Bayesian comparable Comparative COVID-19 Effect effective Effectiveness Efficacy Evidence expected generalisability healthcare high risk hospitalisation ICU admission identify individual infected individual infected with SARS-CoV-2 invasive ventilation moderate monoclonal antibody Mortality network Network meta-analysis neutralising outcome Pairwise comparison patient population patients patients treated Placebo predict Rate RCT reaction reduce mortality reducing reduction in relative risk risk reduction serious AE severe COVID-19 statistically significant reduction systematic review therapy treatment effect vaccination variant [DOI] 10.1038/s41598-022-22431-6 PMC 바로가기
Comparative Assessment of the Inhibitory Potential of the Herbicide Glyphosate and Its Structural Analogs on RGD-Specific Integrins Using Enzyme-Linked Immunosorbent AssaysArticle Published on 2022-10-172022-11-16 Journal: International Journal of Molecular Sciences [Category] COVID19(2023년), SARS, 치료기술, [키워드] Activation AMPA assessment binding biochemical Cell Comparative demonstrated derivative ECM ELISA enzyme-linked immunosorbent enzyme-linked immunosorbent assay Extracellular matrix fibrinogen glycoprotein glyphosate Herbicide ingredient inhibition inhibitory effect integrin Integrins integrins αVβ3 metabolite metabolites pathway physiological functions Polymer Potential Protein Receptor binding domain SARS-CoV-2 receptor SARS-COV-2 receptor binding domain Spike protein structural analogs the SARS-CoV-2 Total α5β1 αllbβ3. [DOI] 10.3390/ijms232012425 PMC 바로가기