A hybrid random forest deep learning classifier empowered edge cloud architecture for COVID-19 and pneumonia detectionResearch article Published on 2022-12-012022-10-05 Journal: Sensors (Basel, Switzerland) [Category] 치료기술, [키워드] Accuracy Affect Algorithm Classifier cloud computing complex computation conducted COVID-19 COVID19 CT scan dataset datasets deep deep learning detect diagnose effective Efficiency evaluate False positives forest global pandemic Healthcare industry heat Heat Transfer Search algorithm identify immunization inefficient Interaction less lung CT scan methodology offer outcomes overcome Patient Pneumonia predict PROTECT random Random forest resource Support the patient virus Web services X-ray [DOI] 10.1016/j.eswa.2022.118227 [Article Type] Research article
Modeling the Enzymatic Mechanism of the SARS-CoV-2 RNA-Dependent RNA Polymerase by DFT/MM-MD: An Unusual Active Site Leading to High Replication RatesArticle Published on 2022-09-122022-11-15 Journal: Journal of Chemical Information and Modeling [Category] SARS, 유전자 메커니즘, 치료제, [키워드] absence Activation Antiviral assist cellular compensated computation COVID-19 diffusion duplication Efficiency Enzymes highlight histidine Inclusion infecting Infection lack leading less Lower lysine mechanism modeling nucleotide Pandemics performed polymerase polymerases Rate reactive reactivity Replication replication of SARS-CoV-2 RNA RNA genome RNA viruses RNA-dependent RNA polymerase SARS-CoV-2 genome Site subsequent the SARS-CoV-2 viral genome Viral RNA virus [DOI] 10.1021/acs.jcim.2c00802 PMC 바로가기
SARS-CoV-2 genomic epidemiology: data and sequencing infrastructureSARS-CoV-2 게놈 역학: 데이터 및 시퀀싱 인프라Article Published on 2022-09-012022-09-11 Journal: Future Microbiology [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] available data computation country COVID-19 case Critical develop Epidemiology funds genomic Genomic surveillance identify implementation Influenza initiative lack Low- and middle-income countries mobilization molecular Molecular epidemiology Next-generation sequencing next-generation sequencing platforms Outbreaks Oxford Nanopore MinION platform SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 genomes SARS-CoV-2 sequencing Sequencing significantly higher Support Surveillance viral lineages whole-genome whole-genome sequencing [DOI] 10.2217/fmb-2021-0207 PMC 바로가기 [Article Type] Article
Reciprocal perspective as a super learner improves drug-target interaction prediction (MUSDTI) Research Published on 2022-08-022022-10-05 Journal: Scientific Reports [Category] 신약개발, [키워드] binary classification binding affinity computation computational method Course Critical database Davis Diseases Drug discovery drug-target drug-target interaction effort experiment experimental design generate IMPROVE interact Interaction Meta outperform Perspective physically predictor Protein public health Reciprocal student transfer [DOI] 10.1038/s41598-022-16493-9 [Article Type] Research
Rapid surveillance of COVID-19 by timely detection of geographically robust, alive and emerging hotspots using Particle Swarm OptimizerResearch article Published on 2022-07-012022-10-05 Journal: Applied Geography [Category] Coronavirus, 치료기술, [키워드] acute respiratory syndrome affected America analyzed applied Brazil computation confirmed case coronavirus Coronavirus disease 2019 country COVID-19 death detect Government help hospital hotspot Hotspot detection identify Incubation period India inefficient less likelihood ratio outbreak pandemic Particle Particle swarm optimizer performance Rapid Result robust Russia SARS-CoV-2 significantly Spatio-temporal analysis study period Surveillance the United State virus World Health Organization Wuhan [DOI] 10.1016/j.apgeog.2022.102719 [Article Type] Research article
Mobile sensors based platform of Human Physical Activities Recognition for COVID-19 spread minimizationResearch article Published on 2022-07-012022-10-05 Journal: Computers in biology and medicine [Category] 치료기술, [키워드] accelerometer Accuracy activities activity Activity classification activity recognition Classifier collected computation concerning Contact tracing continuous monitoring COVID-19 COVID-19 pandemic dataset determine Diseases effective Effectiveness evaluate EWS feature GPS Gyroscope highest Human human behavior Infection infection risk Long Mobile pandemic platform prevalent Probability random Recognition recognize Research risk smartphone sensors Spread Support System tracing [DOI] 10.1016/j.compbiomed.2022.105662 [Article Type] Research article
COVID-DAI: A novel framework for COVID-19 detection and infection growth estimation using computed tomography imagesCOVID-DAI: 컴퓨터 단층 촬영 이미지를 사용한 COVID-19 감지 및 감염 성장 추정을 위한 새로운 프레임워크Article Published on 2022-06-012022-09-11 Journal: Microscopy research and technique [Category] 변종, 치료기술, [키워드] affecting Alpha Analysis approach assist Beta calculate can not classification complex complicate computation Computed tomography coronavirus COVID-19 COVID-19 infection COVID-19 pandemic COVID-19 segmentation COVIDx dataset datasets Delta DenseNet-77 Diagnosis Efficacy ENhance evaluated example Frame framework Gamma growth healthy healthy samples high mortality rate Infection infection growth estimation. Initially introduced module other disease other diseases overcome parameters Patient patients performed pneumonia images predict Prevent Quantitative reducing risk of death robust Segmentation severity similarity the patient Time frame Treatment UNET variants Variation virus was performed [DOI] 10.1002/jemt.24088 PMC 바로가기 [Article Type] Article
In Silico Evaluation of Paxlovid’s Pharmacometrics for SARS-CoV-2: A Multiscale ApproachSARS-CoV-2에 대한 Paxlovid의 약리학의 실리코 평가: 다중 규모 접근Article Published on 2022-05-202022-09-11 Journal: Viruses [Category] COVID19(2023년), SARS, 치료제, [키워드] agent agent-based model Antiviral approach cause component computation diffusion diffusion coefficient feature highest identify in silico in vitro in vivo Intervention mathematical multiscale mathematical modeling Nirmatrelvir outcome Paxlovid Pharmacometrics present profiles replicate Ritonavir SARS-CoV-2 sensitivity spatio-temporal dynamics temporal dynamics tissue damage virus virus diffusion. [DOI] 10.3390/v14051103 PMC 바로가기 [Article Type] Article
Estimation of the basic reproduction number of Alpha and Delta variants of COVID-19 pandemic in Iran이란에서 COVID-19 전염병의 알파 및 델타 변이체의 기본 번식 수 추정Article Published on 2022-05-172022-09-11 Journal: PLoS ONE [Category] COVID19(2023년), SARS, 변종, [키워드] 95% CI Alpha alpha and delta variants Alpha variant applied basic reproduction number Bayesian change changes in computation contagious COVID-19 COVID-19 pandemic Delta delta variant effective Efficiency estimation exponential growth Exponential growth rate growth growth rate Iran mathematical mathematical model Maximum likelihood pandemic Rate statistical model time interval variant variants virus virus spread [DOI] 10.1371/journal.pone.0265489 PMC 바로가기 [Article Type] Article
Safety and efficacy of BCG re-vaccination in relation to COVID-19 morbidity in healthcare workers: A double-blind, randomised, controlled, phase 3 trialResearch article Published on 2022-05-122022-10-05 Journal: EClinicalMedicine [Category] 유전자 메커니즘, 임상, [키워드] 1:1 95% CI analyses Analysis BCG BCG vaccination Breastfeeding Cape Capital childhood computation computing Council COVID-19 COVID-19 testing died Donor double-blind Dream Efficacy enrolled Epigenetic evaluated Evidence female finding FIVE foundation functional funding had no hazard ratio healthcare healthcare worker hospitalisation hypersensitivity hypothesised Immunocompromised Infrastructure innate immune system introduced Investment IQR median age medical doctors morbidity morbidity and mortality non-specific Nurses occurred pandemic participant phase 3 trial placebo-controlled trial pregnant Prevent PROTECT provided randomised recruited reduction Registered resource respiratory tract infection Respiratory tract infections Safety SARS-CoV-2 SARS-COV-2 infection severe COVID-19 disease severity South Africa statistically significant Swedish Symptoms the placebo group trained immunity Treatment Tuberculosis Vaccine were assessed [DOI] 10.1016/j.eclinm.2022.101414 [Article Type] Research article