2023 HRS/EHRA/APHRS/LAHRS Expert Consensus Statement on Practical Management of the Remote Device ClinicEHRA Document Published on 2023-05-192024-09-05 Journal: Europace [Category] update2024, [키워드] alerts Cardiovascular implantable electronic device CIED connectivity Device clinic programming remote monitoring [DOI] 10.1093/europace/euad123 PMC 바로가기 [Article Type] EHRA Document
2023 HRS / EHRA / APHRS / LAHRS Expert Consensus Statement on Practical Management of the Remote Device ClinicGuidelines Published on 2023-05-192024-09-05 Journal: Journal of Arrhythmia [Category] update2024, [키워드] alerts Cardiovascular implantable electronic device CIED connectivity Device clinic programming remote monitoring [DOI] 10.1002/joa3.12851 PMC 바로가기 [Article Type] Guidelines
Protocol for high-throughput screening of ACE2 enzymatic activators to treat COVID-19-induced metabolic complicationsArticle Published on 2022-08-042022-10-04 Journal: STAR protocols [Category] SARS, 신약개발, [키워드] ACE2 bioinformatics candidate Complete Complication complications connectivity database drug High throughput ccreening immunology in silico Map other disease protocol structural biology treat Virtual screening [DOI] 10.1016/j.xpro.2022.101641 PMC 바로가기 [Article Type] Article
Exploring the potential mechanism of emetine against coronavirus disease 2019 combined with lung adenocarcinoma: bioinformatics and molecular simulation analyses폐 선암과 결합된 코로나바이러스 질병 2019에 대한 에메틴의 잠재적 메커니즘 탐색: 생물정보학 및 분자 시뮬레이션 분석Article Published on 2022-06-222022-09-11 Journal: BMC Cancer [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Analysis Atla binding bioinformatics bioinformatics analyses BTK CCL20 conducted connectivity coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Cox proportional hazard DDP4 differentially expressed docking DPP4 drug drugs effective Emetine ENhance exhibited furin groups IL6 inhibit Intersection lack LDHA lung lung adenocarcinoma Map MD simulation MIF molecular molecular docking molecular dynamics Molecular simulation MPro network network pharmacology Patient performed potential mechanism potential mechanisms PRF1 Prognosis protease Replication replication of SARS-CoV-2 risk SARS-CoV-2 Screen screened SDK1 SERPING1 severe acute respiratory syndrome Coronavirus SLC6A4 target therapeutic target Transcriptome TRPA1 Tumor tumor immunity ZIC5 [DOI] 10.1186/s12885-022-09763-2 PMC 바로가기 [Article Type] Article
The Biggest Challenges Resulting from the COVID-19 Pandemic on Gender-Related Work from Home in Biomedical Fields—World-Wide Qualitative Survey AnalysisArticle Published on 2022-03-062022-10-29 Journal: International Journal of Environmental Research an [Category] Coronavirus, MERS, SARS, [키워드] affected Analysis Anxiety benefit biomedical fields Burnout caused challenge Concentration connectivity country COVID-19 COVID-19 impact Depression Efficiency evaluated fear finding Gender Health home include infected with COVID-19 lack less lockdown lockdowns males participant performed positive Pressure point professional public policy Qualitative qualitative international survey analysis raising reported response social interaction Stress survey Symptoms were expressed while women work working Working from home [DOI] 10.3390/ijerph19053109 PMC 바로가기 [Article Type] Article
An in silico analysis identifies drugs potentially modulating the cytokine storm triggered by SARS-CoV-2 infection실리코 분석은 SARS-CoV-2 감염에 의해 유발된 사이토카인 폭풍을 잠재적으로 조절하는 약물을 식별합니다Article Published on 2022-01-312022-09-10 Journal: Scientific Reports [Category] 신약개발, 유전자 메커니즘, 치료제, [키워드] “cytokine storm” addition Analysis anti-inflammatory properties anti-inflammatory property approach BALF Bronchoalveolar lavage fluid cause causes Computational biology and bioinformatics connectivity COVID-19 COVID-19 mortality COVID-19 pandemic COVID-19 patient Cytokines Data mining dataset drug Effect expected female hormone glucocorticoid Glucocorticoids Health help human cell lines identify immune response immune responses in silico analysis in vitro data Inflammatory Map MEK inhibitor modulating molecules Mortality negative regulation pathology pathway Pathways PKC predicted reveal SARS-CoV-2 SARS-COV-2 infection small molecule Small molecules supported the cytokine storm these compounds Transcription Transcriptome transcriptomic data Treatment triggered [DOI] 10.1038/s41598-022-05597-x PMC 바로가기 [Article Type] Article
Identification of potentially anti-COVID-19 active drugs using the connectivity MAP연결 맵을 사용하여 잠재적으로 항 -CovID-19 활성 약물의 확인Research Article Published on 2022-01-272022-09-10 Journal: PLoS ONE [Category] SARS, 신약개발, 유전자 메커니즘, 치료제, [키워드] activating AMPK Analysis Anti-inflammatory applied Cancer cells catabolic Cell characterization Compound connectivity coronavirus coronavirus disease Coronavirus disease-19 COVID-19 Cyclooxygenase database deleterious effect deleterious effects Dexamethasone drug Drug repurposing emergency response favor fluorometholone gene expression profile Gene expression profiles generate glucocorticoid Glucocorticoid receptor growth identification identify infected cells interfere involved lipid metabolism Map MDM2 metabolism modulate nitric oxide nitric oxide synthase organism Other other compounds Oxide p53 pandemic pathway proliferative reaction receptor resource respiratory Severe acute respiratory syndrome severe acute respiratory syndrome-coronavirus-2 Signaling tissue Transmission treat virus [DOI] 10.1371/journal.pone.0262751 PMC 바로가기 [Article Type] Research Article
Distinguishing gene flow between malaria parasite populations말라리아 기생충 집단 사이의 유전자 흐름을 구별합니다Research Article Published on 2021-12-202022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, 말라리아, [키워드] Analysis analyzed approach complementary conditions connectivity death descent disease disease control disperse distinguishing drug-resistant effort epidemiological evaluate gene flow Genetic genetic marker Genetic markers genomic Genomic surveillance geographic location geographic locations Guidance identity implementation implication include Infection information interpretability Interpretation Local malaria malaria control malaria parasite malaria parasites Metrics Migration Multiple National observation observations P. falciparum parasite Population populations public health question sampling sequence similar studies Spread strain Surveillance understanding whole genome sequence [DOI] 10.1371/journal.pgen.1009335 PMC 바로가기 [Article Type] Research Article
A Pro-Inflammatory Gut Microbiome Characterizes SARS-CoV-2 Infected Patients and a Reduction in the Connectivity of an Anti-Inflammatory Bacterial Network Associates With Severe COVID-19Cellular and Infection Microbiology Published on 2021-11-172022-10-31 Journal: Frontiers in Cellular and Infection Microbiology [Category] COVID-19, MERS, SARS, [키워드] 16S rRNA gene Actinobacteria analyzed Anti-inflammatory Associate Bacterial Bacteroide Bacteroidete Bifidobacterium Blood Care CD8 characterized connectivity contribute COVID-19 COVID-19 illness COVID-19 severity decrease Dysbiosis dysregulated Enterobacteriaceae exhibited Faecalibacterium Gut gut microbiome composition gut microbiota Health hospital Hyperinflammatory Immune cell immune response immune responses infected with SARS-CoV-2 intestinal microbiota marker Microbiome mild COVID-19 illness network Patient patients pro-inflammatory Prospective Study Proteobacteria quantified reduction in SARS-CoV-2 SARS-CoV-2 infected patient SARS-CoV-2 positive patient Sequencing severe COVID-19 illness severity Streptococcus T cell was increased [DOI] 10.3389/fcimb.2021.747816 PMC 바로가기 [Article Type] Cellular and Infection Microbiology
Strategies to identify candidate repurposable drugs: COVID-19 treatment as a case example후보자 용도를 식별하기위한 전략 : 사례로서 Covid-19 치료Review Published on 2021-11-162022-08-31 Journal: Translational Psychiatry [Category] SARS, 신약개발, 임상, 진단, 치료제, [키워드] approach Bioinformatic Brain candidate drugs case study CNS complex connectivity COVID-19 COVID-19 pandemic disorders drug Drug repurposing drug therapies drugs example identify library machine-learning Map Molecular neuroscience Neurological disorder Neurological disorders Neuropsychiatric offer overcome Pharmacology promise Repository Research signature Strategy therapy treat Treatment [DOI] 10.1038/s41398-021-01724-w PMC 바로가기 [Article Type] Review