The prominent role of a CDR1 somatic hypermutation for convergent IGHV3-53/3-66 antibodies in binding to SARS-CoV-2SARS-CoV-2에 결합하는 수렴형 IGHV3-53/3-66 항체에 대한 CDR1 체세포 과돌연변이의 두드러진 역할Article Published on 2022-12-012022-09-12 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 진단, [키워드] acute respiratory syndrome Analysis antibodies antibody antibody affinity binding binding affinity Cdr1 contributed Coronavirus-2 COVID-19 Frequency functional germline gene Humoral immunity IGHV3-53/3-66 knowledge mAb mAbs monoclonal monoclonal antibody Mutation other coronaviruses SARS-CoV-2 Somatic hypermutation somatic hypermutations Treatment [DOI] 10.1080/22221751.2022.2063074 PMC 바로가기 [Article Type] Article
Neutralizing antibodies to SARS-CoV-2 variants of concern including Delta and Omicron in subjects receiving mRNA-1273, BNT162b2, and Ad26.COV2.S vaccinesArticle Published on 2022-12-012022-11-15 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] Ad26.COV2.S Ad26.COV2.S vaccine antibody B.1.1.529 B.1.1.7 B.1.351 B.1.617.2 Beta BNT162b2 BNT162b2 vaccine booster center contributed Control COVID-19 Delta dose Effectiveness elicited faster FIVE Gamma immunization moderate mRNA-1273 mRNA-based vaccine Mutation Neutralizing Neutralizing antibodies neutralizing antibody omicron P.1 postvaccination prevention Protein pseudovirus receiving recipient recommendation robust SARS-CoV-2 SARS-CoV-2 vaccine SARS-CoV-2 variant subject Support vaccination Vaccine vaccine efficacy variants of concern variants of concern (VOCs) VoC VOCs wild type [DOI] 10.1002/jmv.28032 PMC 바로가기
Proportion of asymptomatic infection and nonsevere disease caused by SARS-CoV-2 Omicron variant: A systematic review and analysisArticle Published on 2022-12-012022-11-16 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 변종, [키워드] 95% CI 95% confidence interval Analysis Asymptomatic asymptomatic infection booster dose caused children China Clinical severity CNKI concerning conducted contributed COVID-19 COVID-19 patient Delta disease estimate implication Infection Infrastructure less Meta-analysis omicron outcome patients predominant proportion SARS-CoV-2 SARS-CoV-2 variants searched significantly higher study group subgroup analysis systematic review vaccination variant variants was performed Web of Science were excluded [DOI] 10.1002/jmv.28066 PMC 바로가기
Combination therapy with remdesivir and immunomodulators improves respiratory status in COVID-19: A retrospective studyArticle Published on 2022-12-012022-11-15 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 치료제, [키워드] 95% confidence interval Analysis Baricitinib baseline benefit body mass index combination therapy Concomitant contributed control group coronavirus disease COVID-19 COVID-19 patient COVID-19 patients Day Diabetes Mellitus examined faster greater hazard ratio immunomodulator immunomodulators IMPROVE in both group independent investigated median outcome Oxygen administration Patient patients Prognostic factors Remdesivir respiratory recovery retrospective Retrospective study severity single-center study standard treatment supplemental oxygen survival synergistic therapy Tocilizumab treated two group [DOI] 10.1002/jmv.28037 PMC 바로가기
Building-level wastewater surveillance of SARS-CoV-2 is associated with transmission and variant trends in a university settingArticle Published on 2022-12-012022-11-16 Journal: Environmental research [Category] COVID19(2023년), SARS, 변종, [키워드] Alpha variant analyzed associations Building-level surveillance Clinical data clinical testing collected complement Concentration contributed COVID-19 COVID-19 case creating Epidemiology genetic mutation hotspot identify include indicate Intervention Isolation less log N1 and N2 Nucleocapsid gene positive positive control quantification quarantine repeated reported Research SARS-CoV-2 SARS-CoV-2 RNA second wave South spring statistical significance statistically significant Surveillance Transmission university variant variants of concern Viral RNA Viral transmission VOCs Wastewater-based epidemiology [DOI] 10.1016/j.envres.2022.114277 PMC 바로가기
Research progress on vaccine efficacy against SARS-CoV-2 variants of concern우려되는 SARS-CoV-2 변이체에 대한 백신 효능 연구 진행Review Published on 2022-11-302022-09-11 Journal: Human vaccines & immunotherapeutics [Category] COVID19(2023년), SARS, 변종, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus addition caused contributed coronavirus COVID-19 COVID-19 vaccine declined Delta Efficacy Epidemic epidemic wave Epidemics Health Organization Immune escape Measures Neutralizing Neutralizing antibodies omicron Omicron variants pathogenicity Prevention and control Protective Research research and development SARS-CoV-2 SARS-CoV-2 variant severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 triggered vaccination Vaccine vaccine efficacy variant variant of concern variants variety VoC VOCs WHO World Health Organization [DOI] 10.1080/21645515.2022.2057161 PMC 바로가기 [Article Type] Review
Tracking SARS-CoV-2 in rivers as a tool for epidemiological surveillanceArticle Published on 2022-11-202022-11-15 Journal: The Science of the total environment [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] activities Analysis Bacteria Caldera can be used characterized collected Concentration Contamination contributed correlated correlation COVID-19 COVID-19 cases discharge epidemiological epidemiological situation epidemiological surveillance evaluate fecal health authorities Human Human tracers impacted limit microbiologically negatively affected normalization normalized not affected plant quantified receiving reflected reported river Rivers impacted by wastewater RNase P RT-qPCR Salta SARS-CoV-2 SARS-CoV-2 surveillance significant increase similarity Support Surveillance target Viral concentration water quality [DOI] 10.1016/j.scitotenv.2022.157707 PMC 바로가기
Mortality among hospitalized COVID-19 patients during surges of SARS-CoV-2 alpha (B.1.1.7) and delta (B.1.617.2) variantsArticle Published on 2022-11-072022-11-16 Journal: Scientific Reports [Category] SARS, 변종, [키워드] 95% CI Admission Alpha B.1.1.7 B.1.617.2 conducted contributed COVID-19 death Delta died evaluate Factor high mortality rate higher risk hospital hospitalizations hospitalized COVID-19 patient hospitalized patient hospitalized patients ICU Iran lack Nurse nutritional status occurred Patient patients with COVID-19 physician proportion risk of COVID-19 SARS-CoV-2 significantly significantly higher Tehran variant [DOI] 10.1038/s41598-022-23312-8 PMC 바로가기
Cross-cultural comparison of nudging effects for environmental protection: A case-study of risk-averse attitudes toward disposable plasticsArticle Published on 2022-11-032022-11-16 Journal: PLoS ONE [Category] 비임상, [키워드] Analysis attribute benefit Canada caused conducted contributed correlated country COVID-19 cross-cultural Effect effect size effective Effects Factors identify IMPROVE individual information intervention effect Japan limit Linear regression model Machiavellianism positive attitude Randomized controlled trial risk significant effect suggested Support threat traits variety were measured [DOI] 10.1371/journal.pone.0277183 PMC 바로가기
Prevalence of antibodies against SARS-CoV-2 in the Norwegian population, August 2021Article Published on 2022-11-012022-11-15 Journal: Influenza and Other Respiratory Viruses [Category] COVID19(2023년), SARS, 진단, [키워드] absence age Anti-nucleocapsid antibodies antibody automatically children collected conducted confirmed COVID-19 case contributed COVID-19 COVID-19 case COVID-19 pandemic COVID-19 vaccination CrI cross-sectional cumulative estimate Estimated flow cytometric IgG antibody individual Infection Laboratory National Norway nucleocapsid nucleocapsid protein Prevalence RBD Receptor binding domain registry data residual SARS-CoV-2 SARS-CoV-2 antibody SARS-COV-2 infection SARS-CoV-2 seroprevalence sera seropositive sample Seroprevalence the spike protein vaccination were measured women [DOI] 10.1111/irv.13024 PMC 바로가기