HBV Core-specific CD4+ T cells correlate with sustained viral control upon off-treatment in HBeAg-positive chronic hepatitis B patientsArticle Published on 2023-05-012023-06-13 Journal: Antiviral Research [Category] B형 간염, [키워드] CD4(+) T cells Chronic HBV infection core NA withdrawal viral control [DOI] 10.1016/j.antiviral.2023.105585
Metabolic interventions improve HBV envelope-specific T-cell responses in patients with chronic hepatitis Barticle Published on 2023-03-282024-09-05 Journal: Hepatology international [Category] update2024, [키워드] ACAT inhibitors core envelope eosinophil HBV Metabolic interventions Mitochondria-targeted antioxidants polyphenolic compounds RDW-CV T-cell responses [DOI] 10.1007/s12072-023-10490-4 PMC 바로가기 [Article Type] article
Characterization of Intracellular Precore-Derived Proteins and Their Functions in Hepatitis B Virus-Infected Human HepatocytesArticle Published on 2023-02-282023-06-13 Journal: mBio [Category] B형 간염, Fulltext, [키워드] Chimpanzee core HBV Hepatitis B virus Infection precore primary human hepatocytes Replication [DOI] 10.1128/mbio.03501-22 PMC 바로가기
Severe COVID-19 outcomes after full vaccination of primary schedule and initial boosters: pooled analysis of national prospective cohort studies of 30 million individuals in England, Northern Ireland, Scotland, and WalesArticle Published on 2022-10-152022-11-16 Journal: Lancet (London, England) [Category] COVID19(2023년), SARS, 변종, [키워드] 95% CI adjusted age analyses Analysis aRR association B.1.1.529 benefit BNT162b2 booster booster dose Booster vaccine calculated ChAdOx1 nCoV-19 Chronic kidney disease Committee Comorbidities Comorbidity conducted core covariates COVID-19 COVID-19 hospitalisation COVID-19 infection COVID-19 therapeutics COVID-19 vaccination current death dominant Edinburgh England event group Health health condition high risk hospitalisation identify immunisation Immunosuppressant increased risk individual initial Innovation Ireland male Medical Research Council meta-analyses Moderna mortality data mRNA-1273 Multimorbidity National of BNT162b2 offer older adult outcome outcomes Oxford-AstraZeneca per 1000 person-year per 1000 person-years Pfizer-BioNTech Poisson regression model primary care prospective cohort prospective cohort study rate ratio receiving reduced reduced risk remained risk risk factor RT-PCR testing SARS-COV-2 infection Scottish severe COVID-19 Sex those with comorbidity university vaccination Vaccine vaccine dose vaccine group variant [DOI] 10.1016/S0140-6736(22)01656-7 PMC 바로가기
COVID-19 from the perspective of otorhinolaryngology: An analysis of bibliometricsArticle Published on 2022-09-232022-11-15 Journal: Frontiers in Public Health [Category] SARS, 치료기술, [키워드] 2019 novel coronavirus Analysis analytics archive article articles authors bibliometric analysis citation CiteSpace clinical Collection core coronavirus coronavirus disease country COVID-19 COVID-19 research database detect disease Diseases European feature foundation globe highest index Jin manifestation Metrics MOST NHS original Otolaryngological manifestations Otorhinolaryngology outbreak pandemic Patient Perspective Quantitative Research SARS-CoV-2 Science Symptom Symptoms technology The United States Thoma Topic Trust university virus VOSviewer Web of Science Wuhan, China [DOI] 10.3389/fpubh.2022.1002686 PMC 바로가기
SARS-CoV-2 Production, Purification Methods and UV Inactivation for Proteomics and Structural StudiesArticle Published on 2022-09-082022-11-16 Journal: Viruses [Category] SARS, 유전자 메커니즘, [키워드] acute respiratory syndrome biosafety can be used cell activation conditions core Coronavirus-2 COVID-19 died downstream effective experiments faster handling inactivated inactivation Laboratory Microscopy pandemic pathogenicity Production purification resulting SARS-CoV-2 Sequencing Seven significantly size exclusion structural studies. sucrose cushion ultracentrifugation UV inactivation virus [DOI] 10.3390/v14091989 PMC 바로가기
Loneliness in pregnant and postpartum people and parents of children aged 5 years or younger: a scoping reviewArticle Published on 2022-09-072022-11-15 Journal: Systematic Reviews [Category] 치료제, [키워드] Adults children CINAHL Cochrane Library Collection conducted core COVID-19 pandemic Depression detect Effect Elsevier Evidence Health Healthcare professional help highest identify incidence inclusion criteria increase inquiry instance loneliness Loneliness in parenthood Loneliness in pregnancy Maternal Maternal loneliness Mental nine Older Open Science Framework OVID parent parental Parental loneliness parents Perinatal Perinatal loneliness populations Pregnancy pregnant Prevalence ProQuest protocol PsycINFO ranged Research risk scoping review sensitive indicator study participant Topic was measured Web of Science [DOI] 10.1186/s13643-022-02065-5 PMC 바로가기
The in vitro replication phenotype of hepatitis B virus (HBV) splice variant Sp1Article Published on 2022-09-012023-06-13 Journal: Virology [Category] B형 간염, [키워드] core HBx Hepatitis B virus precore Replication SP1 splicing [DOI] 10.1016/j.virol.2022.07.005
Conserved Lysine Residues of Hepatitis B Virus Core Protein Are Not Required for Covalently Closed Circular DNA FormationArticle Published on 2022-08-102023-06-13 Journal: Journal of Virology [Category] B형 간염, Fulltext, [키워드] capsid cccDNA core Hepatitis B virus Infection lysine Polyadenylation posttranslational modification Replication Transcription [DOI] 10.1128/jvi.00718-22 PMC 바로가기
Attractive targeted sugar bait phase III trials in Kenya, Mali, and Zambia케냐, 말리, 잠비아에서 매력적인 표적 설탕 미끼 3상 시험Clinical Trial Published on 2022-08-092022-09-11 Journal: Trials [Category] 말라리아, 임상, 치료제, [키워드] adaptive ARMS Attractive targeted sugar bait children Cluster cluster separation Cluster-randomized controlled trial Clusters Cohort Contamination Controlled trial core covariate covariates COVID-19 pandemic detect determine dinotefuran Effects External validity Follow-up Imbalance IMPROVE incidence include insecticidal insecticide interim analysis internal validity Intervention Kenya kill Longevity malaria morbidity mosquito density Open-label open-label design phase III trial Prevalence Primary outcome Primary outcomes randomization receive reduce reduction in reductions in Restricted resulting risk Sample size secondary outcome strength Structure sugar threat Transmission transmission pattern Trial Two-arm Validity Variation vector vector control vectors [DOI] 10.1186/s13063-022-06555-8 PMC 바로가기 [Article Type] Clinical Trial