EDP-514 in healthy subjects and nucleos(t)ide reverse transcriptase inhibitor-suppressed patients with chronic hepatitis BArticle Published on 2022-12-012023-06-13 Journal: Antiviral therapy [Category] B형 간염, [키워드] capsid assembly modulator Chronic Hepatitis B core inhibitor core protein allosteric modulator Hepatitis B virus Pharmacodynamics pharmacokinetics Safety [DOI] 10.1177/13596535221127848
Novel developments of hepatitis B: treatment goals, agents and monitoring toolsReview Published on 2019-02-012023-06-16 Journal: Expert review of clinical pharmacology [Category] B형 간염, [키워드] antiviral therapy cirrhosis core protein allosteric modulator covalently closed circular DNA cure Genome editing global elimination HBV RNA Hepatitis B core-related antigen Hepatitis B virus Hepatocellular carcinoma immunomodulator Integrated DNA prevention programmed cell death protein 1 RNA interfering gene silencer therapeutic vaccine vaccination viral entry inhibitor. [DOI] 10.1080/17512433.2019.1567327 [Article Type] Review
Hepatitis B core protein as a therapeutic targetReview Published on 2017-12-012023-06-18 Journal: Expert opinion on therapeutic targets [Category] B형 간염, [키워드] cccDNA Chronic Hepatitis B core antigen core protein core protein allosteric modulator cure HBx protein immune response nucleocapsid surface antigen Transcription translation Virology [DOI] 10.1080/14728222.2017.1397134 [Article Type] Review