Review of the impact of COVID-19 on male reproduction, and its implications on assisted reproductive technology servicesReview Published on 2022-12-012023-07-10 Journal: Zygote (Cambridge, England) [Category] COVID19(2023년), [키워드] Coronavirus COVID-19 cross-contamination fertility preservation Infectious disease reproductive health [DOI] 10.1017/S0967199421000666 [Article Type] Review
Fragment-based in silico design of SARS-CoV-2 main protease inhibitorsSARS-CoV-2 주요 프로테아제 억제제의 단편 기반 in silico 설계Article Published on 2021-10-012022-09-11 Journal: Chemical biology & drug design [Category] SARS, 신약개발, 치료제, [키워드] 3CLpro approach AutoDock AutoDock vina binding binding affinity binding mode binding pocket co-crystallized Compound conformation conformations coronavirus Coronavirus COVID-19 crystal structure domain Drug discovery eight fragment fragment-based drug discovery generate Glide in silico inhibitor interactions linear combination linker main protease Mpro 3CLpro MD simulation MPro multivalency. Precision protease Protein Data Bank provided SARS-CoV-2 SARS-CoV-2 main protease SARS-CoV-2 replication screened selected small molecule Small molecules starting point Structure structures suggested therapeutic strategy were used X-ray X-ray crystal structure [DOI] 10.1111/cbdd.13914 PMC 바로가기 [Article Type] Article
A COVID-Positive 52-Year-Old Man Presented With Venous Thromboembolism and Disseminated Intravascular Coagulation Following Johnson & Johnson Vaccination: A Case-StudyEmergency Medicine Published on 2021-07-142022-10-31 Journal: Cureus [Category] COVID-19, [키워드] Activation acute respiratory syndrome Ad26.COV2.S vaccine administration Adverse antibodies AstraZeneca benefit Bilateral Blood Care caused CDC center Complication Computed tomography Concentration conducted consolidations Control coronavirus Coronavirus COVID-19 coronavirus disease COVID-19 COVID-19 patient CTA D-dimer D‐dimer deep vein thrombosis (DVT) Deep venous thrombosis Deterioration Disseminated intravascular coagulation Disseminated intravascular coagulation (DIC) distribution drug DVT Dyspnea effective elevated endotracheal FDA finding food growth ICU immune immune complex increase Inflammation intensive care Intervention intravascular coagulation intubation Johnson & Johnson johnson and johnson vaccine less lobar Lungs Man manifestation moderate Moderna mRNA-based vaccine Occurrence oxygen pandemic Patient Pfizer Platelet Pneumonia positive airway pressure prevention pro-thrombotic Prothrombin time Pulmonary emboli recipient recipients reported required response risk saddle pulmonary embolism SARS-CoV-2 SARS-CoV2 infection segmental artery similarity specificity Supplemental oxygen therapy the SARS-CoV-2 the vaccine Thromboembolism thrombosis thrombotic thrombotic thrombocytopenic thrombocytopenia Thrombus transferred Vaccine venous venous thromboembolism (VTE) was performed worsened [DOI] 10.7759/cureus.16383 PMC 바로가기 [Article Type] Emergency Medicine
AI-guided discovery of the invariant host response to viral pandemics바이러스 전염병에 대한 불변 숙주 반응의 AI 유도 발견Research Paper Published on 2021-06-112022-09-11 Journal: EBioMedicine [Category] MERS, 바이오마커, 진단, 치료제, [키워드] “cytokine storm” abrogate ACE2 acting analyzed Angiotensin converting enzyme (ACE)-2 Antiviral antiviral agent Apoptosis approach Artificial intelligence/machine learning Boolean equivalent clusters candidate drugs cause cell senescence center clinical conserved Cooperative Coronavirus COVID-19 coronavirus disease Coronavirus disease 2019 COVID-19 cytokine Cytokine storm dataset determine Diego disease severity EIDD-2801 elevated ENCODE entry of SARS-CoV-2 epithelial facilitate fatal COVID-19 fatal disease fatality finding Fund funding hamster Healthcare system High-dose host cells Host immune response host response Human IL15 IL15RA immune response immunologist implicated in viral Interleukin 15 (IL15) knowledge limit limits LJI lung Lung alveoli lung epithelial Lungs myeloid cell myeloid cells natural killer (NK) cells Neutralizing antibodies neutralizing antibody NIH NK cell office over Pandemics paradoxical Patient plasma Plasma levels President Program Quantitative receptor scientist signature STEM stem cell subset supported System therapeutic to define transcriptomic University of California utility Viral virus was used [DOI] 10.1016/j.ebiom.2021.103390 PMC 바로가기 [Article Type] Research Paper
Use of the Hayami diffusive wave equation to model the relationship infected–recoveries–deaths of Covid-19 pandemicOriginal Paper Published on 2021-04-292022-11-01 Journal: Epidemiology and Infection [Category] COVID-19, MERS, SARS, [키워드] SIRD compartmental models Analysis application comparable compartmental model contamination rate Coronavirus COVID-19 country death diffusive wave equation Diseases distribution Epidemiology Evolution Hayami kernel function highlight hydraulic hydrology IMPROVE knowledge mathematical formulation pandemic parameter robust transfer unit hydrograph [DOI] 10.1017/S0950268821001011 PMC 바로가기 [Article Type] Original Paper
Immunotherapy for COVID-19: Evolving treatment of viral infection and associated adverse immunological reactionsCOVID-19에 대한 면역요법: 바이러스 감염 및 관련 면역학적 부작용의 치료 진화Review Published on 2021-04-012022-09-12 Journal: Transfusion and apheresis science : official journ [Category] MERS, SARS, 진단, 치료법, [키워드] administration Adsorption Analysis Anti-viral drugs approved AstraZeneca average biological marker clinical combination vaccine convalescent Coronavirus convalescent plasma Coronavirus COVID-19 Coronavirus inflammation Coronavirus neutralizing antibodies Coronavirus vaccines Course Covid 19 lymphopenia. COVID-19 dose effective Efficacy FDA Guidance immune immunological reaction Immunotherapy include indication infected patient Infection Inflammation lymphopenia Moderna monoclonal antibodies mRNA vaccine Neutralizing neutralizing antibody Pfizer plasma produced Quantitative Recombinant protein recruited Safe simian adenovirus-vectored vaccine single dose stability subjects T-cell Treatment trials Vaccine Vaccines viral infection virus [DOI] 10.1016/j.transci.2021.103093 PMC 바로가기 [Article Type] Review
Assessing the relationship between ground levels of ozone (O 3 ) and nitrogen dioxide (NO 2 ) with coronavirus (COVID-19) in Milan, ItalyArticle Published on 2020-06-052023-06-14 Journal: The Science of the total environment [Category] MERS, SARS, [키워드] Air surface nitrogen dioxide (NO2) Air surface ozone (O3) Climate variables Coronavirus COVID-19 NOAA satellite data Planetary Boundary Layer (PBL) [DOI] 10.1016/j.scitotenv.2020.140005 PMC 바로가기 [Article Type] Article
Assessing the relationship between surface levels of PM2.5 and PM10 particulate matter impact on COVID-19 in Milan, ItalyArticle Published on 2020-06-022023-06-15 Journal: The Science of the total environment [Category] MERS, SARS, [키워드] Air quality Coronavirus COVID-19 Meteorological parameters NOAA satellite data Particulate matter (PM2.5 and PM10) [DOI] 10.1016/j.scitotenv.2020.139825 PMC 바로가기 [Article Type] Article