Accelerated Recovery: The Role of Oral Steroid in the Management of Herpes Zoster Ophthalmicus-Related OphthalmoplegiaFamily/General Practice Published on 2023-12-152024-09-04 Journal: Cureus [Category] 대상포진, [키워드] corticosteroid treatment Herpes zoster ophthalmicus (HZO) herpes zoster ophthalmicus-related ophthalmoplegia (hzoro) oculomotor nerve palsy (omp) third cranial nerve (oculomotor nerve) palsy Third nerve palsy [DOI] 10.7759/cureus.50553 PMC 바로가기 [Article Type] Family/General Practice
Corticosteroid treatment in severe patients with SARS-CoV-2 and chronic HBV co-infection: a retrospective multicenter studyMulticenter Study Published on 2022-11-282023-06-11 Journal: BMC Infectious Diseases [Category] B형 간염, SARS, [키워드] Co-infection corticosteroid treatment COVID-19 HBV. [DOI] 10.1186/s12879-022-07882-6 PMC 바로가기 [Article Type] Multicenter Study
Predictors of carbapenem-resistant Enterobacteriaceae (CRE) strains in patients with COVID-19 in the ICU ward: a retrospective case-control studyArticle Published on 2022-10-012022-11-16 Journal: The Journal of international medical research [Category] COVID19(2023년), SARS, 치료기술, [키워드] 95% CI 95% confidence interval acquisition acute respiratory syndrome Admission carbapenem carbapenem-resistant Enterobacteriaceae Care case-control study coronavirus corticosteroid treatment COVID-19 COVID-19 patient COVID-19 patients death determine enrolled Enterobacteriaceae hazard ratio ICU identify increased the risk independent risk factor Infection Invasive mechanical ventilation isolate Klebsiella Length majority Mortality mortality data Odds ratio Patient patients with COVID-19 patients without COVID-19 retrospective risk risk factor Risk factors significantly higher strain subdistribution Treatment two groups [DOI] 10.1177/03000605221129154 PMC 바로가기
Clinical Effect of Early administration of Tocilizumab Following the Initiation of Corticosteroid Therapy for Patients with COVID-19Article Published on 2022-08-012022-10-05 Journal: Journal of infection and chemotherapy : official j [Category] COVID19(2023년), SARS, 임상, 진단, 치료기술, [키워드] acute respiratory syndrome addition administration analyzed baseline blood cell count C-reactive protein caused clinical Clinical characteristics combination therapy coronavirus Corticosteroid corticosteroid therapy corticosteroid treatment Corticosteroids COVID-19 determine drug early administration Effect effective Efficacy evaluated global pandemic groups hospital Hospitalized Initiation maximum body temperature not significantly different oxygen-free day Patient patients with COVID-19 Result SARS-CoV-2 significant decrease significantly higher significantly lower significantly more survival rate Tocilizumab tocilizumab administration treated treating COVID-19 two groups white with COVID-19 Wuhan [DOI] 10.1016/j.jiac.2022.08.021 [Article Type] Article
Prolonged SARS-CoV-2 infection associated with long-term corticosteroid use in a patient with impaired B-cell immunityB 세포 면역이 손상된 환자의 장기간 코르티코스테로이드 사용과 관련된 장기간의 SARS-CoV-2 감염Case Reports Published on 2022-07-012022-09-12 Journal: Journal of infection and chemotherapy : official j [Category] COVID19(2023년), SARS, 진단, [키워드] B-cell Cell-mediated immunity Corticosteroid corticosteroid treatment Corticosteroids COVID-19 dose IgA IgM Immunity Immunocompromised immunocompromised individuals Infection Non-Hodgkin Lymphoma Patient PCR persistence Prolonged reduction Reinfection remained Remdesivir rituximab SARS-CoV-2 SARS-CoV-2 IgG SARS-COV-2 infection Sequencing severe COVID-19 significantly susceptible treat treated Treatment treatment period viral clearance viral shedding viral strain [DOI] 10.1016/j.jiac.2022.02.006 PMC 바로가기 [Article Type] Case Reports
Major candidate variables to guide personalised treatment with steroids in critically ill patients with COVID-19: CIBERESUCICOVID studyObservational Study Published on 2022-07-012022-10-04 Journal: Intensive care medicine [Category] 임상, [키워드] Administered administration affected age Analysis assessment Bacterial baseline benefit Care clinically Corticosteroid corticosteroid treatment Corticosteroids covariate COVID-19 COVID-19 patient Critically ill Critically ill patient Dexamethasone dosage dose doses of corticosteroid early administration Evidence failure higher risk hospitalisation ICU ICU admission ICUs Illness severity in-hospital mortality increased risk Inflammation information intensive care interaction term Invasive mechanical ventilation investigated Laboratory lower risk Major mechanical ventilation Modification Mortality multivariable analysis no effect nosocomial Observational cohort study organ damage Patient patients with COVID-19 performed personalised Pneumonia potential benefit Primary outcome Protective receiving severe coronavirus disease severity Significant SOFA Spanish steroid subgroup subgroups subgroups of patient symptom onset systemic corticosteroid Treatment use of corticosteroid variable with COVID-19 [DOI] 10.1007/s00134-022-06726-w PMC 바로가기 [Article Type] Observational Study
RAGE has potential pathogenetic and prognostic value in nonintubated hospitalized patients with COVID-19RAGE는 삽관되지 않은 COVID-19 입원 환자에서 잠재적인 병리학적 및 예후적 가치가 있습니다.Clinical Trial Published on 2022-05-092022-09-11 Journal: JCI Insight [Category] MERS, 바이오마커, 임상, 진단, 치료법, [키워드] adjusted age Antibody Response Antigen association bamlanivimab baseline Biomarker Biomarkers BMI clinical Clinical outcome clinical outcomes Clinical practice clinical trial Concentration correlated correlation Corticosteroid corticosteroid treatment COVID-19 Cox regression CRP Cytokines diabetes Diabetes Mellitus enrolled Factor highest Hospitalized hospitalized patient hospitalized patients IL-6 Illness severity Indicator likelihood mechanically ventilated nucleocapsid antigen oxygen participant Participants patients with COVID-19 plasma positive Prognostic value Pulmonology quartile RAGE rate ratio receptor renal impairment risk of death Sex significantly lower Spearman supplemental oxygen sustained systemic inflammation tested Trial Viral viral burden Viral load was measured was used were used with COVID-19 [DOI] 10.1172/jci.insight.157499 PMC 바로가기 [Article Type] Clinical Trial
Pitfalls of Early Systemic Corticosteroids Home Therapy in Older Patients with COVID-19 PneumoniaBrief Report Published on 2022-02-172022-10-31 Journal: Geriatrics [Category] COVID-19, [키워드] acute respiratory distress Administered Admission age ARDS benefit Care Clinical outcome clinical outcomes Control corticosteroid therapy corticosteroid treatment Corticosteroids COVID-19 determine early phase ECT Effectiveness enrolled Escalation home home therapy Hospitalization Hospitalized ICU in-hospital mortality median no difference older patient older people pandemic PaO Patient Pneumonia progression progression of disease reducing SARS-COV-2 infection significant difference SOFA score subject syndrome systemic the disease transfer with COVID-19 [DOI] 10.3390/geriatrics7010021 PMC 바로가기 [Article Type] Brief Report
Clinico-histopathologic and single-nuclei RNA-sequencing insights into cardiac injury and microthrombi in critical COVID-19중요한 COVID-19에서 심장 손상 및 미세 혈전에 대한 임상 조직 병리학 및 단일 핵 RNA 시퀀싱 통찰력Clinical Trial Published on 2022-01-252022-09-10 Journal: JCI Insight [Category] 임상, 진단, 치료기술, 치료제, [키워드] Acute cardiac injury Analysis antiplatelet association bioinformatics Biomarkers biomarkers of inflammation C-reactive protein cardiac injury Cardiology cardiovascular disease cause clinical factors Cohort conducted controls Corticosteroid corticosteroid treatment COVID-19 Critical enrichment erythrocyte sedimentation erythrocyte sedimentation rate etiology Extracellular matrix Features fibrinolysis fibroblast heart hearts identify In-hospital increased mortality Injury microthrombi Molecular pathology myocarditis Necrosis New York City pathophysiology Patient potential therapeutic target prevalent Prospective Study RNA-sequencing sedimentation rate Sequencing analysis Signaling tested therapeutic anticoagulation Therapies therapy transcriptomic were used [DOI] 10.1172/jci.insight.154633 PMC 바로가기 [Article Type] Clinical Trial
Effects of IFIH1 rs1990760 variants on systemic inflammation and outcome in critically ill COVID-19 patients in an observational translational study관찰 중개 연구에서 중환자 COVID-19 환자의 전신 염증 및 결과에 대한 IFIH1 rs1990760 변이체의 효과Research Article Published on 2022-01-212022-09-10 Journal: eLife [Category] 변종, [키워드] 95% CI 95% confidence interval analyzed Anti-inflammatory anti-inflammatory phenotype applied benefit Blood cause Cell changes in clinical trial clinical trials coding Cohort Concentration Corticosteroid corticosteroid treatment Corticosteroids COVID COVID-19 COVID-19 patient COVID-19 patients Critically ill death determine Dexamethasone discharge distribution drug Effect ENCODE experiment expression Factor funding Gene Expression greater hazard ratio healthy volunteer healthy volunteers help hospital host response Human ICU IFIH1 IL-6 IL6 immune Immune cell immune cells immune system Impact in-silico increase in individual Infection Inflammation Inflammatory response intensive care intensive care unit Laboratory less lower expression Lung injury MDA5 mechanical ventilation mediators moderate to severe modulate mononuclear cell mononuclear cells Mortality outcome outcomes Pathways Patient patients patients with moderate peripheral Peripheral blood Peripheral blood mononuclear cells pharmacogenomics physician populations pro-inflammatory mediators prospectively studied Protein recognize Red reduce regulate respond risk RNA serum Serum IL-6 severe COVID-19 Spain steroid Steroids supported survived systemic inflammation team the patient translational treat treated Treatment triggered variant variants Variation Viral viral infections virus viruses were measured [DOI] 10.7554/eLife.73012 PMC 바로가기 [Article Type] Research Article