COVID-19 Vaccination and Public Health Countermeasures on Variants of Concern in Canada: Evidence From a Spatial Hierarchical Cluster AnalysisCOVID-19 예방 접종 및 캐나다의 우려 변종에 대한 공중 보건 대책: 공간 계층적 클러스터 분석의 증거Article Published on 2022-05-312022-09-11 Journal: JMIR Public Health and Surveillance [Category] COVID19(2023년), SARS, 변종, [키워드] Alpha Analysis analyzed B.1.1.7 B.1.351 B.1.617.2 Beta booster dose Canada characterized Cluster cluster analysis Clusters community transmission concern countermeasure COVID-19 COVID-19 incidence COVID-19 mitigation debate declining Delta effort Evidence exhibited Factors Gamma Government Health authority Hierarchical hierarchical cluster analysis identify Impact implementation Kruskal-Wallis test machine learning mass vaccination measure mobility index moderate Population populations Prevalence prevalence rate preventive measures proportion PROTECT Public public health public health authorities public health measure public health measures receive Research significantly strength stringency index vaccination vaccination coverage Vaccine Vaccines variants variants of concern VoC VOCs was used [DOI] 10.2196/31968 PMC 바로가기 [Article Type] Article
Hospitalised patients with breakthrough COVID-19 following vaccination during two distinct waves in Israel, January to August 2021: a multicentre comparative cohort study2021년 1월부터 8월까지 이스라엘에서 두 차례에 걸쳐 백신 접종 후 획기적인 COVID-19로 입원한 환자: 다기관 비교 코호트 연구Multicenter Study Published on 2022-05-012022-09-11 Journal: Eurosurveillance [Category] COVID19(2023년), SARS, 변종, [키워드] 95% CI Admission affected age Alpha variant Alpha wave booster Breakthrough infection breakthrough infections Cohort cohort study congestive heart failure countermeasure COVID-19 death Delta delta variant Delta wave greater heart failure hospitalised COVID-19 patient hospitalised COVID-19 patients Immunosuppressed Immunosuppression Inpatients less median time men multicentre occurred Older Older age outcome Patient patients Primary outcome Protective SARS-CoV-2 suggested vaccination Vaccine vaccine dose variant Ventilation vulnerability waning immunity [DOI] 10.2807/1560-7917.ES.2022.27.20.2101026 PMC 바로가기 [Article Type] Multicenter Study
SARS-CoV-2 mRNA vaccine induced higher antibody affinity and IgG titers against variants of concern in post-partum vs non-post-partum womenSARS-CoV-2 mRNA 백신은 산후 여성과 비 산후 여성에서 우려되는 변이체에 대해 더 높은 항체 친화도 및 IgG 역가를 유도했습니다.Article Published on 2022-03-012022-09-11 Journal: EBioMedicine [Category] MERS, SARS, 변종, 진단, [키워드] affinity Affinity maturation Amino acid amino acids antibody antibody affinity Antibody binding antibody neutralisation titres Beta both groups characterisation comparable controls countermeasure COVID-19 declined Delta described domain FDA groups help IgG titer immune response immune responses in both groups initiative knowledge Limited manuscript mRNA mRNA vaccine mutant neutralisation neutralisation titre neutralising ability plasma plasma antibody profile RBD SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants significantly higher spike supported sustained tested vaccination Vaccination strategies Vaccination strategy Vaccine vaccine-induced antibody response variants of concern VoC VOCs women [DOI] 10.1016/j.ebiom.2022.103940 PMC 바로가기 [Article Type] Article
Melatonin: highlighting its use as a potential treatment for SARS-CoV-2 infection멜라토닌: SARS-CoV-2 감염에 대한 잠재적 치료제로서의 용도 강조Review Published on 2022-02-202022-09-10 Journal: Cellular and Molecular Life Sciences [Category] COVID19(2023년), MERS, SARS, 진단, 치료제, [키워드] analyses animals anti-inflammatory agent antioxidant Care caused Combination coronavirus Coronaviruses countermeasure COVID-19 COVID-19 disease COVID-19 patient Cytokine storm death death rate demonstrated diminishe disease dose doses drug drugs duration of hospitalization Effect effective Efficacy Health Health care highlighting Hospitalization humans Hypoxia-inducible factor 1-α lack medications melatonin molecular network Numerous Pandemics Phospholipase A2 Potential treatment predicted Prophylactic rationale reduce reduced safety profile SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections Sepsis severity Severity of infection Side effect Side effects Toxicity treat treated Treatment treatments for COVID-19 Viral viral infection viral infections viruses [DOI] 10.1007/s00018-021-04102-3 PMC 바로가기 [Article Type] Review
Online Education Plight and Countermeasures for MBBS in Chinese Regional Medical Schools Based on the OBE Concept During COVID-19 PandemicPublic Health Published on 2022-01-212022-10-31 Journal: Frontiers in Public Health [Category] Coronavirus, MERS, SARS, [키워드] China Chinese concept countermeasure countermeasures COVID-19 COVID-19 pandemic education MBBS OBE online education Regional regional medical schools School [DOI] 10.3389/fpubh.2021.806809 PMC 바로가기 [Article Type] Public Health
Antibody affinity maturation and cross-variant activity following SARS-CoV-2 mRNA vaccination: Impact of prior exposure and sexResearch paper Published on 2021-12-102022-11-01 Journal: EBioMedicine [Category] COVID-19, SARS, [키워드] Advancing Affinity maturation Alliance antibody antibody affinity Award binding center contribute convalescent convalescent individual convalescent individuals countermeasure COVID-19 Department described determine dose FDA female females finding funding Human Impact individual Infection Infectious disease initiative knowledge Limited male manuscript maturation mRNA mRNA vaccination mutant mutants naïve neutralization titer neutralizing antibody NIAID NIH no difference number Participants Plasmon prefusion profile Pseudovirus neutralization assay RBD Receptor binding domain resonance SARS-CoV-2 Science sera service Sex sex differences significantly higher SPR supported surface the SARS-CoV-2 university Vaccine vaccine dose variants variants of concern variants of interest Virus neutralization VOCs VOIs was used [DOI] 10.1016/j.ebiom.2021.103748 PMC 바로가기 [Article Type] Research paper
An Update on Animal Models for Severe Acute Respiratory Syndrome Coronavirus 2 Infection and Countermeasure DevelopmentMicrobiology Published on 2021-11-082022-10-31 Journal: Frontiers in Microbiology [Category] COVID-19, [키워드] ACE2 acute respiratory syndrome animal animal model Appropriate caused coronavirus coronavirus 2 Coronavirus infection countermeasure country COVID-19 COVID-19 pathogenesis Critical development disease manifestation experimental animal model ferret hamsters highly pathogenic Human Infection mechanism mice Model Non-human pandemic pathogenesis of COVID-19 pathogenic Region Research respiratory SARS-CoV-2 Symptom Vaccine Vaccines virus [DOI] 10.3389/fmicb.2021.770935 PMC 바로가기 [Article Type] Microbiology
Knowledge and preventive actions toward COVID-19, vaccination intent, and health literacy among educators in Japan: An online surveyResearch Article Published on 2021-09-202022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] activity affected age Care changes in collected complex countermeasure COVID-19 determine Effect effort engage Factor Gender Government Health implementation improvement information initial investigated Japanese knowledge Linear regression analysis Local measure media National outbreak pandemic pharmacies Physicians receive reliability Spread spread of COVID-19 subsequent Support used data vaccination viral infection wearing mask were used [DOI] 10.1371/journal.pone.0257552 PMC 바로가기 [Article Type] Research Article
Vesicular Stomatitis Virus: From Agricultural Pathogen to Vaccine VectorReview Published on 2021-08-272023-08-29 Journal: Pathogens [Category] E형 간염, [키워드] countermeasure Ebola virus medical countermeasure reverse genetics Vaccine vesicular stomatitis virus VSV VSV-EBOV [DOI] 10.3390/pathogens10091092 PMC 바로가기 [Article Type] Review
Intranasal gene therapy to prevent infection by SARS-CoV-2 variantsSARS-CoV-2 변이체에 의한 감염을 예방하기 위한 비강내 유전자 요법Research Article Published on 2021-07-152022-09-10 Journal: PLoS Pathogens [Category] SARS, 변종, [키워드] ACE2 administration affinity airway angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 animals Antiviral approach bind binding caused Cell combating coronavirus Coronaviruses countermeasure CoV COVID-19 COVID-19 pandemic CoVs demonstrated effective Efficacy evade expression Gene therapy human ACE2 humans immune response improvement infecting Infection Intervention intranasal intranasally less long-lasting monoclonal antibodies monoclonal antibody mouse model nasal Nasal spray neutralize Pandemics pathogenicity pathologic consequence Patient Population pre-existing immunity Prevent Prophylaxis Protein proximal receptor reduce respond SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants SARS-CoV-2 viral secrete significantly Spread tested the patient therapeutic Transmissibility unlikely vaccination Vaccinations Vaccine Vaccines variant variants variants of SARS-CoV-2 Viral viral mutation Viral mutations viral particle Viral particles Viral vector virus Vulnerable populations zoonosis [DOI] 10.1371/journal.ppat.1009544 PMC 바로가기 [Article Type] Research Article