Altered kidney function induced by SARS-CoV-2 infection and acute kidney damage markers predict survival outcomes of COVID-19 patients: a prospective pilot studySARS-COV-2 감염 및 급성 신장 손상 마커에 의해 유도 된 변경된 신장 기능 COVID-19 환자의 생존 결과를 예측합니다 : 전향 적 파일럿 연구Article Published on 2022-12-012022-08-31 Journal: Renal failure [Category] COVID19(2023년), SARS, 바이오마커, [키워드] acute kidney Acute kidney injury adjusted Advancing age Altered Analysis association Biomarker chronic Chronic kidney disease collaboration Comorbidities Comorbidity Control coronavirus disease Coronavirus disease 2019 covariate covariates COVID-19 COVID-19 patient COVID-19 patients creatinine Cumulative rates cystatin C death demonstrated elevated examined group groups Hospitalized ICU intensive care intensive care unit investigated Kaplan-Meier method kidney kidney damage Kidney disease Kidney function Kidney function tests Kidney injury literature marker morbidity multivariable Cox regression outcome participant pilot study predict Predictive Predictive value Proteinuria retained risk factor Risk factors SARS-COV-2 infection serum serum creatinine Sex significant difference statistically subject survival survival analysis the Kaplan-Meier method Treatment Urine with COVID-19 [DOI] 10.1080/0886022X.2022.2032743 PMC 바로가기 [Article Type] Article
Mapping post-traumatic stress disorder symptoms and quality of life among residents of Wuhan, China after the COVID-19 outbreak: A network perspectiveResearch article Published on 2022-12-012022-10-05 Journal: Journal of affective disorders [Category] 진단, [키워드] approach Attention changes in checklist Chinese Civilian Community conducted connection covariates COVID-19 COVID-19 outbreak cross-sectional cross-sectional survey emotional examined Follow-up General population initial lack life limitation mapping mental health network analysis objective outbreak pandemic participant Perspective Post-traumatic stress disorder Post-traumatic stress disorder symptoms Quality Quality of life Result self-report measure Study design Symptom Version were measured World Health Organization Wuhan Wuhan residents Wuhan, China [DOI] 10.1016/j.jad.2022.08.074 [Article Type] Research article
High levels of soluble RAGE are associated with a greater risk of mortality in COVID-19 patients treated with dexamethasoneArticle Published on 2022-11-052022-11-15 Journal: Respiratory Research [Category] SARS, 바이오마커, [키워드] Admission association Biomarker Biomarkers Blood level Clinical management Control correlated covariates COVID-19 COVID-19 patient COVID-19 patients death Determination Dexamethasone died disease severity elevated Follow-up greater host inflammatory response IL-6 increased risk independent Infection Inflammation investigated Mortality NEWS2 Patient patient population patients patients treated Pearson positive positive individual predict prognostic RAGE receptor reduce risk SARS-CoV-2 score second wave significantly lower sRAGE. subject Teaching treated Treatment university [DOI] 10.1186/s12931-022-02220-5 PMC 바로가기
An explainable model of host genetic interactions linked to COVID-19 severityArticle Published on 2022-10-262022-11-16 Journal: Communications Biology [Category] 변종, 유전자 메커니즘, [키워드] age and gender Analysis classifiers Cohort contributing to covariates COVID-19 COVID-19 severity dataset Factor Features Follow-up Genetic GWAS high accuracy highest Host identify immune pathways immune system increased risk Inflammatory Interaction Italian patients MCC molecular mechanism offer outcome Patient phenotypic predict predicted Predictive screened several variant Severe COVID-19 Infection severity Signaling significantly Stratification stratified Support tested therapeutic intervention Thoracic variant viral infection WES with COVID-19 [DOI] 10.1038/s42003-022-04073-6 PMC 바로가기
Severe COVID-19 outcomes after full vaccination of primary schedule and initial boosters: pooled analysis of national prospective cohort studies of 30 million individuals in England, Northern Ireland, Scotland, and WalesArticle Published on 2022-10-152022-11-16 Journal: Lancet (London, England) [Category] COVID19(2023년), SARS, 변종, [키워드] 95% CI adjusted age analyses Analysis aRR association B.1.1.529 benefit BNT162b2 booster booster dose Booster vaccine calculated ChAdOx1 nCoV-19 Chronic kidney disease Committee Comorbidities Comorbidity conducted core covariates COVID-19 COVID-19 hospitalisation COVID-19 infection COVID-19 therapeutics COVID-19 vaccination current death dominant Edinburgh England event group Health health condition high risk hospitalisation identify immunisation Immunosuppressant increased risk individual initial Innovation Ireland male Medical Research Council meta-analyses Moderna mortality data mRNA-1273 Multimorbidity National of BNT162b2 offer older adult outcome outcomes Oxford-AstraZeneca per 1000 person-year per 1000 person-years Pfizer-BioNTech Poisson regression model primary care prospective cohort prospective cohort study rate ratio receiving reduced reduced risk remained risk risk factor RT-PCR testing SARS-COV-2 infection Scottish severe COVID-19 Sex those with comorbidity university vaccination Vaccine vaccine dose vaccine group variant [DOI] 10.1016/S0140-6736(22)01656-7 PMC 바로가기
Palmitoylethanolamide Reduces Proinflammatory Markers in Unvaccinated Adults Recently Diagnosed with COVID-19: A Randomized Controlled TrialArticle Published on 2022-10-062022-11-15 Journal: The Journal of Nutrition [Category] COVID19(2023년), SARS, 바이오마커, [키워드] adhesion molecules age anti-inflammatory effect Antigen assigned baseline Biomarker Blood BMI C-reactive protein CDC chronic condition coin toss Concentration conducted Controlled coronavirus disease covariates COVID-19 COVID-19 complications COVID-19, SARS-COV-2 Cytokines diagnosed with COVID-19 Diagnosis dietary supplements double-blind dysregulated immune response Effect exacerbate ferritin group Health IL-1β IL-2 IL-6 implicated indicated individual infected with COVID-19 infections infectious conditions Inflammation inflammatory mediator intercellular Linear regression model mechanism Multiple outcomes P-selectin palmitoylethanolamide participant Placebo placebo tablet positive test result Primary outcome produced proinflammatory promote randomized placebo-controlled trial Randomly receive reduced reported RT-PCR secretion severity Sex significantly stratified treatment effect [DOI] 10.1093/jn/nxac154 PMC 바로가기
Barotrauma in COVID 19: Incidence, pathophysiology, and effect on prognosisResearch article Published on 2022-10-012022-10-05 Journal: Clinical imaging [Category] 진단, [키워드] 95% CI barotrauma Chest radiography Cohort conducted coronavirus covariates COVID COVID-19 COVID-19 patients death determine emphysema incidence increase in increased risk intubated COVID-19 patient intubation IQR mechanical ventilation mechanically ventilated median time Mortality objective outcome pathophysiology Patient patient mortality patients died patients with COVID-19 performed Pneumomediastinum Pneumothorax Prognosis Result Retrospective study Risk factors secondary outcome the median [DOI] 10.1016/j.clinimag.2022.06.014 [Article Type] Research article
Long-term survival benefit of male and multimorbid COVID-19 patients with 5-day remdesivir treatmentObservational Study Published on 2022-08-312022-10-05 Journal: Journal of Global Health [Category] SARS, 변종, 임상, [키워드] all-cause mortality Alpha Analysis Anemia antiviral medication benefit center clinical condition Cohort collected Comorbidity COPD coronavirus disease Course covariates COVID-19 COVID-19 pandemic COVID-19 patient diabete effective Efficacy epidemiological situation Frequency greater group hospitalized patients Hungary Inpatient lack male men Mortality multiple comorbidities multivariate Observational cohort study outcome parenchymal participant Patient performed Primary outcome RDV real-world data receiving Remdesivir retrospective risk reduction Significant significantly lower significantly more specific patient groups Standard of care supplementary oxygen survival Treatment Treatment protocol treatment regimen university Vaccinations variant [DOI] 10.7189/jogh.12.05031 PMC 바로가기 [Article Type] Observational Study
Social Vulnerability and Rurality Associated With Higher Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection-Induced Seroprevalence: A Nationwide Blood Donor Study-United States, July 2020-June 2021더 높은 중증 급성 호흡기 증후군 코로나바이러스 2(SARS-CoV-2) 감염 유발 혈청 유병률과 관련된 사회적 취약성과 농촌: 전국 헌혈자 연구-미국, 2020년 7월-2021년 6월Article Published on 2022-08-242022-09-12 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 진단, [키워드] acute respiratory syndrome antibody association black Blood Care coronavirus coronavirus 2 coronavirus disease covariates COVID-19 cross-sectional deaths demographics demonstrated effort Health health equity Hispanic index Infection MOST Outbreaks pandemic quantified reduce regression models repeated reported respiratory rural rurality SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 seroprevalence Seroprevalence significantly Social vulnerability study period the United State used data Vaccination strategy vulnerability Washington [DOI] 10.1093/cid/ciac105 PMC 바로가기 [Article Type] Article
Mobility was a significant determinant of reported COVID-19 incidence during the Omicron Surge in the most populous U.S. Counties이동성은 미국에서 가장 인구가 많은 카운티에서 Omicron Surge 동안 보고된 COVID-19 발병의 중요한 결정 요인이었습니다.Article Published on 2022-08-152022-09-11 Journal: BMC Infectious Diseases [Category] SARS, 변종, [키워드] 95% CI 95% confidence interval categories Cohort contrary Course covariates COVID-19 COVID-19 incidence cross-sectional analysis cumulative declined Epidemics exhibiting fatigue fraction Google Google mobility reports household size humans Immune escape incidence infect Infection intrinsic Mobility omicron Omicron variant peaked Perceived risk Principal component principal component analysis principal components question reported risk-mitigating behavior. robustness SARS-CoV-2 Significant susceptible individual susceptible individuals vaccination variant widespread [DOI] 10.1186/s12879-022-07666-y PMC 바로가기 [Article Type] Article