Cramp – Communicable Diseases Research

An Intranasal OMV-Based Vaccine Induces High Mucosal and Systemic Protecting Immunity Against a SARS-CoV-2 Infection

비강내 OMV 기반 백신은 SARS-CoV-2 감염에 대한 높은 점막 및 전신 보호 면역을 유도합니다

Immunology

Published on 2021-12-172022-09-11
Journal: Frontiers in Immunology [Category] SARS, 변종, 진단, 치료기술, 치료제,

[키워드] administer Administered administration Against antibody booster vaccination booster vaccinations candidate vaccine CHO cells clinical development clinical testing control group control groups COVID-19 COVID-19 vaccine COVID-19 vaccines Cramp D614G effective eight greater hamster hamsters Histopathology IgA IgG IgG response immune protection immune response Immunity Immunoglobulin Immunoglobulin G inactivated induce intramuscular intramuscular vaccination intramuscularly intranasal intranasally lesion Local lung Lungs majority membrane vesicles mice mRNA mucosal mucosal immunity Neisseria Neisseria meningitidis Neutralizing antibodies nose offer OMV outer membrane outer membrane vesicle pandemic peptide peptide sequence practicality produced proline Protecting reduced Registered required SARS-CoV-2 SARS-CoV-2 pandemic second vaccination sequence serum Spike protein subunit Subunit vaccine Support systemic the SARS-CoV-2 Transmission vaccination Vaccinations Vaccine variants Vesicle Viral viral entry viral replication Viral vector weight loss
[DOI] 10.3389/fimmu.2021.781280 PMC 바로가기 [Article Type] Immunology

CRAMP deficiency leads to a pro-inflammatory phenotype and impaired phagocytosis after exposure to bacterial meningitis pathogens

CRAMP 결핍은 세균성 수막염 병원체에 노출된 후 염증 유발 표현형과 손상된 식세포작용을 초래합니다.

Research

Published on 2017-09-162024-08-01
Journal: Cell Communication and Signaling : CCS [Category] 폐렴구균 감염증,

[키워드] antimicrobial peptide Cathelicidin Cramp glial cell Innate immunity Signal transduction
[DOI] 10.1186/s12964-017-0190-1 PMC 바로가기 [Article Type] Research