Building-level wastewater surveillance of SARS-CoV-2 is associated with transmission and variant trends in a university settingArticle Published on 2022-12-012022-11-16 Journal: Environmental research [Category] COVID19(2023년), SARS, 변종, [키워드] Alpha variant analyzed associations Building-level surveillance Clinical data clinical testing collected complement Concentration contributed COVID-19 COVID-19 case creating Epidemiology genetic mutation hotspot identify include indicate Intervention Isolation less log N1 and N2 Nucleocapsid gene positive positive control quantification quarantine repeated reported Research SARS-CoV-2 SARS-CoV-2 RNA second wave South spring statistical significance statistically significant Surveillance Transmission university variant variants of concern Viral RNA Viral transmission VOCs Wastewater-based epidemiology [DOI] 10.1016/j.envres.2022.114277 PMC 바로가기
A dataset comprised of binding interactions for 104,972 antibodies against a SARS-CoV-2 peptideArticle Published on 2022-10-262022-11-15 Journal: Scientific Data [Category] COVID19(2023년), SARS, 진단, [키워드] antibody antibody sequences Antigen binding binding interaction binding score can be used CDRs collected creating dataset evaluate in silico include knowledge machine learning models Mutation naïve peptide predicted provide Quantitative quantitative measurement random Region resulting SARS-CoV-2 sequence starting [DOI] 10.1038/s41597-022-01779-4 PMC 바로가기
Murine Hepatitis Virus, a Biosafety Level 2 Model for SARS-CoV-2, Can Remain Viable on Meat and Meat Packaging Materials for at Least 48 HoursArticle Published on 2022-10-262022-11-15 Journal: Microbiology Spectrum [Category] COVID19(2023년), SARS, 치료기술, [키워드] biosafety Biosafety Level 2 bottleneck BSL2 Can condition conditions contribute coronavirus Coronaviruses COVID-19 case creating detectable determine Evidence facilitate Factor FIVE highest hour hpi hygiene inoculated involved material meat MHV Model murine hepatitis virus notable outbreak packaging material. Particles persistence physical physical distancing plant provide reduction reduction in reservoir resulting SARS-CoV-2 Spread spread of COVID-19 steadily decreased Styrofoam survival tested unpaired t test viability Viable viral infectivity virus [DOI] 10.1128/spectrum.01862-22 PMC 바로가기
Multiple Introductions of SARS-CoV-2 Alpha and Delta Variants into White-Tailed Deer in PennsylvaniaArticle Published on 2022-10-262022-11-16 Journal: mBio [Category] COVID19(2023년), SARS, 변종, [키워드] Alpha analyzed animal reservoir bat coronavirus COVID-19 epidemic creating deer Delta Delta variants Epidemics example future infection genomic data help Host Human humans identify independent Infection information Lineage mammals management Multiple nasal swab North America observation occur Odocoileus Odocoileus virginianus positive replicate reported reservoir RT-qPCR SARS-CoV-2 SARS-CoV-2 pandemic significantly spike gene susceptible trajectory Transmission transmissions variant vertebrates white-tail deer white-tailed deer whole genome sequence zoonosis [DOI] 10.1128/mbio.02101-22 PMC 바로가기
Enhanced antibody responses in fully vaccinated individuals against pan-SARS-CoV-2 variants following Omicron breakthrough infectionArticle Published on 2022-10-182022-11-15 Journal: Cell Reports Medicine [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] acute respiratory syndrome ancestral Antibody Response Breakthrough infection coronavirus Course COVID-19 infection creating cross-neutralization cytokine D614G dominant enhanced evade immune Immunity individual induce memory T cell mRNA mRNA vaccination mRNA vaccine neutralization Neutralizing activity neutralizing antibody Neutralizing antibody response Neutralizing antibody titer omicron Omicron BA.1 Omicron BA.2 producing PROTECT recovered patient respond SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants serum T cell T cell immune response the spike protein vaccinated individual vaccination variant variants of concern virus [DOI] 10.1016/j.xcrm.2022.100764 PMC 바로가기
Vaccine hesitancy for coronavirus SARS-CoV-2 in Varanasi IndiaArticle Published on 2022-10-052022-11-15 Journal: Frontiers in Public Health [Category] COVID19(2023년), SARS, 변종, 치료기술, 치료제, [키워드] age association conducted coronavirus coronavirus SARS-CoV-2 COVID-19 creating detect Factor Factors Frequency Gender Government Government of India help India medium MOST North North India overcome participated proportion Region reported SARS-CoV-2 second wave vaccinate vaccination Vaccine Vaccine hesitancy Varanasi variant variants virus [DOI] 10.3389/fpubh.2022.892584 PMC 바로가기
Multi-scale mechanism of antiviral drug-alike phytoligands from Ayurveda in managing COVID-19 and associated metabolic comorbidities: insights from network pharmacologyArticle Published on 2022-10-012022-11-15 Journal: Molecular diversity [Category] COVID19(2023년), SARS, 치료제, [키워드] Antiviral antiviral drugs antiviral immunity APCS approach Ayurveda binding affinity cardiovascular complications Comorbidities Comorbidity COVID-19 creating develop Diabetes Mellitus disorders effective highlighting Host hypertension immunomodulators investigated mechanism molecular docking network network pharmacology novel coronavirus disease Protein target public health regulate Regulatory SARS-CoV-2 SARS-CoV-2 proteins synergistic therapy Traditional virus Wuhan, China [DOI] 10.1007/s11030-021-10352-x PMC 바로가기
A compact, low-cost, and binary sensing (BiSense) platform for noise-free and self-validated impedimetric detection of COVID-19 infected patientsCOVID-19 감염 환자의 소음이 없고 자체 검증된 장애 감지를 위한 소형의 저비용 바이너리 감지(BiSense) 플랫폼Article Published on 2022-10-012022-09-11 Journal: Biosensors & bioelectronics [Category] COVID19(2023년), SARS, 바이오마커, 변종, 치료기술, 치료법, [키워드] acquisition added advancement Alpha Analysis approach Bi-potentiostat Biomarkers biosensor complex components COVID-19 infected patient creating Diagnosis electrical electrochemical biosensing electrode infections less matrix effect multiplex N-protein nasopharyngeal platform point-of-care Protein Quantitative Rapid Rapid tests reliability reported SARS-CoV-2 SARS-CoV-2 nucleocapsid shelf swab samples variant was used [DOI] 10.1016/j.bios.2022.114459 PMC 바로가기 [Article Type] Article
Transchromosomic bovines-derived broadly neutralizing antibodies as potent biotherapeutics to counter important emerging viral pathogens with a special focus on SARS-CoV-2, MERS-CoV, Ebola, Zika, HIV-1, and influenza A virusSARS-CoV-2, MERS-CoV, 에볼라, 지카, HIV-1 및 인플루엔자 A 바이러스에 특히 중점을 두고 중요한 신흥 바이러스 병원체에 대응하는 강력한 생물 치료제로서의 형질전환 소 유래 광범위 중화 항체Review Published on 2022-10-012022-09-11 Journal: Journal of medical virology [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus adjuvant adjuvants Alpha animals antibody antibody-based therapies Antiviral approach approved assist Beta Biotherapeutics blocked bovine bovine-derived biotherapeutics Clinical studies colostrum convalescent coronavirus creating Delta disease Donor E484K Ebola effective Efficiency emerging viruses Epsilon Gamma highlight HIV-1 Human Human immunodeficiency virus human immunodeficiency virus type 1 human infection human infections hyperimmunization immune immunoreactivity Immunotherapy Influenza influenza A influenza A virus Iota K417N L452R Lambda MERS MERS-CoV Middle East Middle East respiratory syndrome Coronavirus mutations N501Y neutralization neutralized Neutralizing Neutralizing activity neutralizing antibody omicron Omicron variants outbreak P681R Pandemics platform polyclonal antibodies polyclonal antibody produced Protective respiratory respiratory syndrome coronavirus robust Safe SARS-CoV-2 serum severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 shown T478K therapeutic option transchromosomic bovines. Vaccine variant variants variants of concern variants of interest Viral viral infection viral infections viral pathogen VOCs VOIs Zika [DOI] 10.1002/jmv.27907 PMC 바로가기 [Article Type] Review
Diagnostic performance of molecular and serological tests of SARS-CoV-2 on well-characterised specimens from COVID-19 individuals: The EDCTP “PERFECT-study” protocol (RIA2020EF-3000)Article Published on 2022-09-212022-11-15 Journal: PLoS ONE [Category] SARS, 변종, 치료기술, [키워드] affecting Amplicon assays Biorepository Care Clinical diagnosis Clinicians collected conducted confirmed case contribute COVID-19 COVID-19 infection creating diagnosing Diagnosis effective effort ELISA ENhance Epidemiology evaluated Evidence facilitate Fatality rate Follow-up Genetic identify IMPROVE individual individuals management measure molecular Molecular assay molecular assays PCR performed platform point-of-care positive protocol real-time qPCR risk SARS-CoV-2 SARS-CoV-2 pandemic SARS-CoV2 sera Serological assay serological test Serological testing specificity specimen strain Swab transfer translate Treatment well [DOI] 10.1371/journal.pone.0273818 PMC 바로가기