Macrophage-based therapeutic approaches for cardiovascular diseasesReview Published on 2024-01-032024-09-05 Journal: Basic Research in Cardiology [Category] update2024, [키워드] Cardiac remodeling Cell therapy CVD Gene therapy immune cells Inflammation iPSC-derived macrophages macrophages Myocardial infarction Non-coding RNA (ncRNA) [DOI] 10.1007/s00395-023-01027-9 PMC 바로가기 [Article Type] Review
Molecular and pro-inflammatory aspects of COVID-19: The impact on cardiometabolic healthArticle Published on 2022-12-012022-11-15 Journal: Biochimica et biophysica acta. Molecular basis of [Category] COVID19(2023년), SARS, 진단, [키워드] affected cardiometabolic cardiovascular Cluster Complication country COVID COVID-19 COVID-19 pandemic COVID-19 severity CVD cytokine cytokine production diabetes Final hallmark Health hypertension IL-6 IL10 IL2 IL4 IL8 immune system increased the risk infected patient Inflammation inflammatory state influence molecular morbidity and mortality obese pathophysiological Patient predictor pro-inflammatory reported resulting SARS-CoV2 systemic damage target type 2 diabete virus [DOI] 10.1016/j.bbadis.2022.166559 PMC 바로가기
Importance of Intermittent Fasting Regimens and Selection of Adequate Therapy on Inflammation and Oxidative Stress in SARS-CoV-2 InfectionArticle Published on 2022-10-142022-11-16 Journal: Nutrients [Category] COVID19(2023년), SARS, 변종, [키워드] acute respiratory syndrome Adequate approach cancers cardiovascular disease chronic disease Chronic diseases communicable disease complementary coronavirus COVID-19 CVD Diabetes Mellitus dietary dietary supplements effective fasting fatty acids feasible hallmark immunomodulatory Importance Inflammation Inflammatory Intermittent intermittent fasting Modification nutraceutical obesity outcome oxidative oxidative stress Patient Polyunsaturated Post-infection quercetin Randomized controlled trial regimen SARS-CoV-2 Selection severe coronavirus disease suggested systemic Therapies time-restricted eating Treatment variant Vitamin vitamins was performed [DOI] 10.3390/nu14204299 PMC 바로가기
Cardiovascular Risks and Outcome in COVID-19 Positive Patients With Cardiovascular Disease Attending Primary Health Care Corporation in Qatar: A Retrospective Cohort StudyResearch article Published on 2022-10-012022-10-05 Journal: Mayo Clinic Proceedings: Innovations, Quality & Outcomes [Category] 치료기술, [키워드] age analyzed Attending B-type natriuretic peptide BNPB-type natriuretic peptide cardiovascular cardiovascular disease cohort study Comorbidity Complication coronavirus disease Corporation COVID-19 COVID-19 patient COVID-19 patients COVID-19Coronavirus disease CVD CVDCardiovascular disease diabete disease electronic medical record Factor greater hematologic higher risk Hospital admission Hospitalization hypertension inclusion criteria increase inpatient admission Kidney disease less liver disorder men morbidity and mortality Multivariate analysis neurologic obesity objective Other outcome Patient patients with COVID-19 patients’ data PHCCPrimary Health Care Corporation positive predict Primary Health Care Corporation problem reported Result risk SARS-CoV-2severe acute respiratory syndrome coronavirus 2 secondary care selected severe acute respiratory syndrome coronavirus 2 survived Symptom tested the median the patient [DOI] 10.1016/j.mayocpiqo.2022.08.001 [Article Type] Research article
Molecular Mechanisms of Ferroptosis and Relevance to Cardiovascular DiseaseArticle Published on 2022-09-012022-11-16 Journal: Cells [Category] 유전자 메커니즘, [키워드] alleviate antioxidants Arrhythmias Atherosclerosis Cardiomyopathy cardiovascular cardiovascular disease Cell cell death characterized conditions Critical CVD cytoplasmic Defense demonstrated detoxify DHODH enzyme activity Evidence expected Fenton reaction Ferroptosis genetic manipulation heart failure implication induce inhibitors Injury involved iron lipid peroxidation LOX membrane Mitochondria mitochondrial mitochondrial membrane molecular mechanism Pathogenesis Pathways peroxidase Protein regulated Relevance ROS therapeutic option [DOI] 10.3390/cells11172726 PMC 바로가기
Gene Variants Related to Cardiovascular and Pulmonary Diseases May Correlate with Severe Outcome of COVID-19심혈관 및 폐 질환과 관련된 유전자 변이가 COVID-19의 심각한 결과와 관련될 수 있음Article Published on 2022-08-042022-09-11 Journal: International Journal of Molecular Sciences [Category] 변종, [키워드] Analysis association cardiovascular cardiovascular diseases Cohort collected correlated COVID-19 COVID-19 patients CVD DRC1 Genetic Genetic variant genetic variants GWAS HADHA identified variant INDEL individual introns nucleotide outcome Poland polymorphism Protective pulmonary pulmonary disease pulmonary diseases risk Risk factors single nucleotide Single nucleotide polymorphism SNP SNPs subset variant variants was performed was used WGS whole-genome sequencing [DOI] 10.3390/ijms23158696 PMC 바로가기 [Article Type] Article
Regulation of cholesterol homeostasis in health and diseases: from mechanisms to targeted therapeutics Reviews Published on 2022-08-022022-10-05 Journal: Signal Transduction and Targeted Therapy [Category] 치료제, [키워드] atherosclerotic atherosclerotic lesion benefit Cancer cancers cardiovascular disease cardiovascular diseases cardiovascular event cardiovascular system Cell cholesterol cholesterol homeostasis cholesteryl esters clinics Critical CVD diabetes disease Diseases Disturbed endothelial events Health inhibiting Intervention Lipid Low-Density Lipoprotein cholesterol maintaining mechanism molecular neurodegenerative nonalcoholic fatty liver obesity Osteoporosis pathway preclinical study Prevent PROTECT Regulation regulatory pathways Research shown target Transport Treatment virus infection [DOI] 10.1038/s41392-022-01125-5 [Article Type] Reviews
Impact of the COVID-19 Pandemic on Cardiovascular Health in 2020: JACC State-of-the-Art ReviewReview article Published on 2022-08-012022-10-05 Journal: Journal of the American College of Cardiology [Category] 진단, [키워드] Admission affected Burden of disease cardiovascular disease cause clinical country COVID-19 COVID-19 pandemic CVD death deaths Effect global mortality Health heterogeneous hospital hospital outcomes Impact in some increases in Mortality occurred pandemic Population health reported Research review significant decrease [DOI] 10.1016/j.jacc.2022.06.008 [Article Type] Review article
Hypocalcemia: A key biomarker in hospitalized COVID-19 patientsResearch article Published on 2022-08-012022-10-05 Journal: Biomedical journal [Category] SARS, 바이오마커, [키워드] addition Admission adult subject Arterial hypertension association Biochemical biomarkers Biomarker blood biochemical calcium calcium concentration Cancer cardiovascular diseases China Chronic diseases Chronic kidney disease chronic obstructive CKD clinical complication Cohort collected Coronavirus disease 2019 COVID-19 COVID-19 patient COVID-19 patients CVD diabetes effective enrolled evaluated hospital hospitalizations hospitalized COVID-19 patient Hypocalcemia identify indicated ionized calcium mandatory material mechanical ventilation obesity outcome parameter Pathologies pathology patients poor prognosis positive correlation presence of comorbidity Previous studies profile Prognosis prognostic biomarker pulmonary disease Result SARS-CoV2 serum severity syndrome the disease [DOI] 10.1016/j.bj.2022.08.005 [Article Type] Research article
Incremental monounsaturated to saturated fat ratio and fibre consumption is associated with a reduction in a composite score of modifiable cardiovascular risk factors: Prospective results from the Moli-sani study Research Published on 2022-07-292022-10-05 Journal: European journal of clinical nutrition [Category] 바이오마커, [키워드] 95%CI Analysis baseline blood lipids C-reactive protein cardiovascular disease cardiovascular risk change changes in clinical factors contributing to CVD dietary enrolled enrolment evaluate fat feature Health median men and women Modification Mortality Non-communicable disease outcome pleiotropic Prospective reduce reduction in reflected Result risk risk factor Risk factors saturated Sociodemographic sub-cohort Variation [DOI] 10.1038/s41430-022-01185-4 [Article Type] Research