A Snake Venom Peptide and Its Derivatives Prevent Aβ 42 Aggregation and Eliminate Toxic Aβ 42 Aggregates In Vitroarticle Published on 2024-07-032024-09-05 Journal: ACS Chem Neurosci [Category] update2024, [키워드] aggregation Aβ42 D-peptide deaggregation peptide Snake venom [DOI] 10.1021/acschemneuro.4c00089 PMC 바로가기 [Article Type] article
A Computer-Aided Approach for the Discovery of D-Peptides as Inhibitors of SARS-CoV-2 Main ProteaseMolecular Biosciences Published on 2022-01-242022-10-31 Journal: Frontiers in Molecular Biosciences [Category] COVID-19, [키워드] 3CL pro 3CLpro approach Area caused cleavage conducted conserved cysteine protease D-peptide drug candidate drug target enzymatic assay Free energy calculation highlighting identify in silico Approach inhibiting inhibitor Mechanics molecular Molecular dynamics simulation nonstructural protein polyprotein pp1a pp1ab problem protease protease active site Protein Replication reported responsible SARS-CoV-2 SARS-CoV-2 main protease structures subsequent surface therapeutic agents Virtual screening virus [DOI] 10.3389/fmolb.2021.816166 PMC 바로가기 [Article Type] Molecular Biosciences