Adverse events following immunization of elderly with COVID-19 inactivated virus vaccine (CoronaVac) in Southeastern Brazil: an active surveillance studyArticle Published on 2022-10-032022-11-15 Journal: Revista do Instituto de Medicina Tropical de São [Category] 진단, [키워드] Active surveillance Administered advanced age Adverse adverse event Brazil center chronic conditions collected Comorbidities Contact CoronaVac COVID-19 vaccine daily living dose doses eight enrolled evaluate event fatigue female frailty headache Healthcare workers home immunization impairment inactivated Inactivated vaccine information injection Mild moderate MOST myalgia participant Population public health receive reference reported Safe severe adverse events team the vaccine vaccination vaccination schedule Vaccine vaccine dose virus with COVID-19 [DOI] 10.1590/S1678-9946202264056 PMC 바로가기
A First View of the Effect of a Trial of Early Mobilization on the Muscle Strength and Activities of Daily Living in Mechanically Ventilated Patients With COVID-19Research article Published on 2022-09-012022-10-05 Journal: Archives of Rehabilitation Research and Clinical Translation [Category] 임상, [키워드] Activities of Daily Living activity Barthel Index Care COVID-19 Daily daily living Early Ambulation Effect functional groups Inpatient intensive care Intervention Japan male manual measure mechanical ventilation Medical Research Council Mobility mobilization muscle Muscle strength no difference objective outcome measure participant Patient patients with COVID-19 postintervention rehabilitation Respiration Result retrospective scale setting severe COVID-19 significantly single-center small sample size statistically significant strength subject Test View [DOI] 10.1016/j.arrct.2022.100201 [Article Type] Research article
Noradrenergic Add-on Therapy with Extended-Release Guanfacine in Alzheimer’s Disease (NorAD): study protocol for a randomised clinical trial and COVID-19 amendments알츠하이머병(NorAD)에서 연장 방출 구안파신을 사용한 노르아드레날린성 추가 요법: 무작위 임상 시험 및 COVID-19 수정안에 대한 연구 프로토콜Article Published on 2022-08-012022-09-11 Journal: Trials [Category] 임상, [키워드] activities activity Add-on therapy addition Adrenergic receptor affected Alzheimer's disease Alzheimer’s disease approved assessment Attention attention deficit baseline Brain burden cholinesterase inhibitor clinical trial Cognition cognitive Combination combination therapy COVID-19 Daily daily living determine disease disorder double-blind dysfunction evaluate Evidence executive Follow-up function Guanfacine Guanfacine. hyperactivity IMPROVE include interview inventory involved locus measure Mild mild to moderate moderate modulating Neuropsychiatric NorAD noradrenergic observation outcome participant pathological change pathological changes pathway Pathways Placebo placebo group placebo-controlled Primary outcome randomised receive receptor Regulation secondary Secondary outcomes Study protocol Symptom symptomatic synergistic synergistic effect Test the placebo group thought Treatment treatment group Trial [DOI] 10.1186/s13063-022-06190-3 PMC 바로가기 [Article Type] Article
A SARS-CoV-2 Outbreak Among Nursing Home Residents Vaccinated with a Booster Dose of mRNA COVID-19 VaccinemRNA COVID-19 백신의 추가 용량으로 예방 접종을 받은 요양원 거주자 사이에서 SARS-CoV-2 발생Article Published on 2022-08-012022-09-11 Journal: Journal of community health [Category] SARS, 변종, [키워드] activities administration B.1.617.2 booster dose caused collected data COVID-19 COVID-19 complications daily living Delta delta variant died dose Effectiveness elderly healthcare worker home hospitalisation Impact Impact of vaccination increased risk Independence individual infected with SARS-CoV-2 interactions Italy median age Mild disease mild symptoms mRNA Nursing nursing home occurred outbreak required resident SARS-CoV-2 severe disease third dose Vaccine variant [DOI] 10.1007/s10900-022-01082-8 PMC 바로가기 [Article Type] Article
SARS-CoV-2 potential drugs, drug targets, and biomarkers: a viral-host interaction network-based analysisSARS-CoV-2 잠재적 약물, 약물 표적 및 바이오마커: 바이러스-숙주 상호작용 네트워크 기반 분석Article Published on 2022-07-132022-09-11 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 바이오마커, 변종, 신약개발, 임상, 치료제, [키워드] Amiodarone Analysis anthracyclines Antibiotics Antiviral antiviral agent Biomarker Blood CDK1 cell cycle CENPF CIT Complete COVID-19 cytarabine daily living diagnostic biomarker Diagnostic biomarkers Differentially expressed genes digitoxin Doxorubicin drug drug target drugs Enhancing enrichment ERG example expression FDA-approved drug FDA-approved drugs FLUOROURACIL gemcitabine global pandemic HMOX1 host cell hydroxyurea identify Infection inhibitors Interaction less mir-93 mitotic MYB omicron Omicron variant pathway Pathways performed Probability prognostic biomarker repositioning retrieved RRM2 SARS-CoV-2 sotalol suggested targets the disease therapeutic TOP2A transcriptomic transmission rate Treatment variant variants viral-host interaction virus [DOI] 10.1038/s41598-022-15898-w PMC 바로가기 [Article Type] Article
One-Year Multidisciplinary Follow-Up of Patients With COVID-19 Requiring Invasive Mechanical VentilationObservational Study Published on 2022-05-012022-10-04 Journal: Journal of cardiothoracic and vascular anesthesia [Category] COVID19(2023년), SARS, 임상, [키워드] activities activity acute phase acute respiratory distress acute respiratory distress syndrome Admission age ARDS Care change Chest computed tomography chest CT scan cognitive coronavirus disease Coronavirus disease 2019 COVID-19 daily living develop discharge discharged Dyspnea Follow-up functional had no hospital hospital discharge ICU improvement IMV intensive care intensive care unit Interaction Invasive mechanical ventilation investigated long-term survival lung Lung recovery majority measurement Mechanical offered Patient patients patients who survived patients with COVID-19 post-intensive care syndrome Prospective Psychological outcome pulmonary fibrosis Quality of life questionnaire receiving reported survival survived survivor syndrome undergo university hospital were assessed with COVID-19 [DOI] 10.1053/j.jvca.2021.11.032 PMC 바로가기 [Article Type] Observational Study
The Impact of COVID-19 on the Initiation of Clinical Trials in Europe and the United StatesCOVID-19가 유럽과 미국의 임상 시험 시작에 미치는 영향Article Published on 2022-05-012022-09-11 Journal: Clinical Pharmacology and Therapeutics [Category] 임상, [키워드] affected Analysis analyzed average clinical clinical trial clinical trials conducted coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 pandemic daily living decrease EU Clinical Trial Europe Impact increase in initiated Initiation less Non-COVID-19 pandemic public health reached reduced regions remained the United State The United States Trial trials United States [DOI] 10.1002/cpt.2534 PMC 바로가기 [Article Type] Article
Rehabilitation in Acute COVID-19 Patients: A Japanese Retrospective, Observational, Multi-Institutional SurveyObservational Study Published on 2022-05-012022-10-05 Journal: Archives of physical medicine and rehabilitation [Category] 임상, [키워드] Activities of Daily Living activity acute COVID-19 Admission changes in condition COVID-19 COVID-19 patient Critical daily living died discharge Factor food functional Gait hospital intake intensive care unit Japan Japanese not applicable outcome Patient patients proportion provided rehabilitation scale survey Symptoms Treatment walking were assessed [DOI] 10.1016/j.apmr.2021.11.004 PMC 바로가기 [Article Type] Observational Study
Passive Samplers, an Important Tool for Continuous Monitoring of the COVID-19 PandemicCOVID-19 전염병의 지속적인 모니터링을 위한 중요한 도구인 수동 샘플러Review Published on 2022-05-012022-09-11 Journal: Environmental science and pollution research inter [Category] COVID19(2023년), SARS, 치료기술, [키워드] battle benefit caused China Community Continuous COVID-19 daily living dimension dimensions effective Epidemiology example Example scenario facilitate global pandemic identify indicate integration measure MONITOR monitoring Nanjing Occurrence outbreak Outbreaks pandemic pandemic progresses Passive Passive sampler positive potential benefit potential benefits provide Region SARS-CoV-2 SARS-CoV-2 detection significantly suppress Vaccine virus wastewater wastewater monitoring Wastewater-based epidemiology while [DOI] 10.1007/s11356-022-19073-6 PMC 바로가기 [Article Type] Review
Difficulty and help with activities of daily living among older adults living alone during the COVID-19 pandemic: a multi-country population-based studyResearch Article Published on 2022-03-042022-10-27 Journal: BMC Geriatrics [Category] Coronavirus, MERS, SARS, [키워드] Activities of Daily Living activity Ageing aging analysed association Care changes in Concentration country COVID-19 COVID-19 pandemic daily living difficulty Domiciliary care English equity Europe examined Factor FIVE Health Service health system help hypothese indicated International less Lithuania Live alone longitudinal longitudinal cohort study male measure National Older older adult Older adults pandemic receive reported Research response Result retirement Sex supplementary material survey Switzerland USA Variation were measured [DOI] 10.1186/s12877-022-02799-w PMC 바로가기 [Article Type] Research Article