Revealing the toxicity of lopinavir- and ritonavir-containing water and wastewater treated by photo-induced processes to Danio rerio and Allivibrio fischeriDanio rerio 및 Allivibrio fischeri에 광유도 공정으로 처리된 로피나비르 및 리토나비르 함유 용수 및 폐수의 독성 공개Article Published on 2022-06-102022-09-11 Journal: The Science of the total environment [Category] 치료제, [키워드] Affect affecting antiviral drug antiviral drugs Bacteria Behavior Chronic toxicity Concentration Contact contact with coronavirus disease Coronavirus disease 2019 COVID-19 Danio drug Ecotoxicity edema Efficiency form hospital Impact increase in indicate Inflammation Lopinavir LOPINAVIR AND RITONAVIR Organisms oxidative stress oxygen parameter Photocatalysis Photolysis physicochemical plants predicted problem protocols reduce Ritonavir shortening significantly survival tail toxic effect Toxicity treated Treatment wastewater water zebrafish [DOI] 10.1016/j.scitotenv.2022.153967 PMC 바로가기 [Article Type] Article
Detoxifying SARS-CoV-2 antiviral drugs from model and real wastewaters by industrial waste-derived multiphase photocatalysts산업폐기물 유래 다상 광촉매로 모델 폐수 및 실제 폐수에서 SARS-CoV-2 항바이러스제 해독Article Published on 2022-05-052022-09-11 Journal: Journal of hazardous materials [Category] COVID19(2023년), SARS, 치료제, [키워드] Ammonium antiviral drug antiviral drugs applied Combination Concentration contrary COVID-19 pandemic Danio Degradation degrade Effect effective Efficiency Embryo highest hydrophilic Industrial Industrial waste Lopinavir LOPINAVIR AND RITONAVIR Multiphase photocatalyst Photocatalysis plant reported resulting Ritonavir SARS-CoV-2 temperature tested Toxicity treated Treatment visible light wastewater water Water pollution Water purification Water purification. X-ray diffraction zebrafish [DOI] 10.1016/j.jhazmat.2022.128300 PMC 바로가기 [Article Type] Article
Intranasal delivery of SARS-CoV-2 spike protein is sufficient to cause olfactory damage, inflammation and olfactory dysfunction in zebrafishSARS-CoV-2 스파이크 단백질의 비강 내 전달은 제브라피쉬에서 후각 손상, 염증 및 후각 기능 장애를 유발하기에 충분합니다Article Published on 2022-05-012022-09-11 Journal: Brain, behavior, and immunity [Category] COVID19(2023년), SARS, 치료기술, [키워드] animal animal models animals Anosmia bind cause Cell characterized cilia Cluster Combined damage Danio direct infection driven by edema endothelial EOG explained expression fish food functional hemorrhage hemorrhages Histopathology implication indicated Infection Inflammation Inflammatory response Inflammatory responses intranasal intranasally Loss of Smell mechanism myeloid cell nasal epithelium non-neuronal cell non-neuronal cells olfactory Olfactory damage olfactory dysfunction olfactory function Olfactory organ olfactory receptor Olfactory receptor expression organ prevalent Protein RBD receptor reduced response SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 S SARS-CoV-2 spike SARS-CoV-2 spike protein sensory neuron spike Spike protein Symptom treated Vaccine Viral protein Viral proteins widespread zebrafish Zebrafish (Danio rerio). [DOI] 10.1016/j.bbi.2022.03.006 PMC 바로가기 [Article Type] Article
Utilizing comparative models in biomedical researchResearch article Published on 2021-08-012022-10-05 Journal: Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology [Category] 비임상, [키워드] biochemical Biochemistry Biomedical research Caenorhabditis elegans Community Comparative Danio developmental disease Drosophila melanogaster example invertebrate issue knowledge less mechanisms pathology physiological Physiology unique vertebrates while Xenopus [DOI] 10.1016/j.cbpb.2021.110593 [Article Type] Research article
Zebrafish as a Translational Model: An Experimental Alternative to Study the Mechanisms Involved in Anosmia and Possible Neurodegenerative Aspects of COVID-19?번역 모델로서의 Zebrafish: 후각 상실과 COVID-19의 가능한 신경퇴행성 측면과 관련된 메커니즘을 연구하기 위한 실험적 대안?Review Published on 2021-05-052022-09-10 Journal: eNeuro [Category] MERS, SARS, 유전자 메커니즘, [키워드] acute respiratory syndrome coronavirus Anosmia aspect Asymptomatic Brain classical Clinical symptoms Cohort cohort of patients conditions coronavirus coronavirus disease coronavirus disease-2019 COVID-19 Danio Effect embryonic embryonic development Encephalitis feature functions Genetic genetic manipulation high availability induce investigated Logistic long-lasting mammalian mechanism neurodegeneration neurologic neurologic disorders neuroscience olfactory Olfactory system organism pandemic pathway Preclinical replications respiratory respiratory manifestations SARS-CoV-2 severe acute respiratory syndrome Coronavirus similarity suggested Symptom Treatment Variability Visual with COVID-19 zebrafish [DOI] 10.1523/ENEURO.0027-21.2021 PMC 바로가기 [Article Type] Review
The SARS-CoV-2 receptor and other key components of the Renin-Angiotensin-Aldosterone System related to COVID-19 are expressed in enterocytes in larval zebrafishMethods & Techniques Published on 2021-03-152022-10-27 Journal: Biology open [Category] COVID-19, [키워드] Analysis Ang II Angiotensin II Apelin blood pressure cause Cell cell type cleaving common cold coronavirus Comorbidity component components conducted Conserved synteny contribute coronavirus coronavirus SARS-CoV-2 COVID-19 Danio Danio rerio degrade diabetes disease Effects Enterocyte enzyme exacerbated expressed expressing expression expression patterns Genes Genome duplication genomic HCoV-229E help hypertension identify Infection intestinal cell investigated mechanism MERS-CoV Middle East obesity ortholog outcome peptide Phylogenetic analysis produced PROTECT RAAS receptor receptors regulate respiratory respiratory inflammation Result SARS-CoV-2 SARS-CoV-2 receptor scRNA-seq Single Cell single-cell specific type subtype susceptible System the SARS-CoV-2 transcriptomes transcriptomics underlying conditions Vascular virus zebrafish [DOI] 10.1242/bio.058172 PMC 바로가기 [Article Type] Methods & Techniques
The SARS-CoV-2 receptor and other key components of the Renin-Angiotensin-Aldosterone System related to COVID-19 are expressed in enterocytes in larval zebrafishMethods & Techniques Published on 2021-03-152022-10-27 Journal: Biology open [Category] Coronavirus, COVID-19, Fulltext, SARS, [키워드] Analysis Ang II Angiotensin II Apelin blood pressure cause Cell cell type cleaving common cold coronavirus Comorbidity component components conducted Conserved synteny contribute coronavirus coronavirus SARS-CoV-2 COVID-19 Danio Danio rerio degrade diabetes disease Effects Enterocyte enzyme exacerbated expressed expressing expression expression patterns Genes Genome duplication genomic HCoV-229E help hypertension identify Infection intestinal cell investigated mechanism MERS-CoV Middle East obesity ortholog outcome peptide Phylogenetic analysis produced PROTECT RAAS receptor receptors regulate respiratory respiratory inflammation Result SARS-CoV-2 SARS-CoV-2 receptor scRNA-seq Single Cell single-cell specific type subtype susceptible System the SARS-CoV-2 transcriptomes transcriptomics underlying conditions Vascular virus zebrafish [DOI] 10.1242/bio.058172 PMC 바로가기 [Article Type] Methods & Techniques