DAVID – Communicable Diseases Research

Recombinant Protein Micelles to Block Transduction by SARS-CoV-2 Pseudovirus

Article

Published on 2022-10-252022-11-16
Journal: ACS Nano [Category] COVID19(2023년), SARS, 변종,

An international observational study to assess the impact of the Omicron variant emergence on the clinical epidemiology of COVID-19 in hospitalised patients

Article

Published on 2022-10-052022-11-16
Journal: eLife [Category] COVID19(2023년), SARS, 변종,

[키워드] adjusted Analysis Appendix approach assumption available data Calabria carrier caused changes in characterisation clinical Clinical outcome Clinical research clinical study collected Commonwealth confidence interval confounders COVID-19 dataset DAVID development Donor emergence Epidemiology European European Commission fatality Foreign foundation Frequency funding global health Google.org group heterogeneity Horizon hospital hospitalised hospitalised patient Imperial College London include infecting Infection Infectious disease International IRCCS ISARIC Italian Joshua less Logistic regression lower mortality Medical Research Council Medicine Melinda Gate Microbiology Ministry of Health network NIHR NIHR HPRU Odds ratio office omicron opportunity outcome Oxford Patient PHE protection Public Health England Rapid relative frequencies reported symptom Research respiratory response responsible Rockefeller Foundation SARS-CoV-2 variant School Semple sensitivity analysis Sriniva study population subset Support supported Symptoms union unit University of Liverpool University of Oxford variant variants viral genomic information viruses with COVID-19
[DOI] 10.7554/eLife.80556 PMC 바로가기

Exploration of the Mechanism of Lianhua Qingwen in Treating Influenza Virus Pneumonia and New Coronavirus Pneumonia with the Concept of “Different Diseases with the Same Treatment” Based on Network Pharmacology

Research Article

Published on 2022-02-082022-10-31
Journal: Evidence-based Complementary and Alternative Medicine : eCAM [Category] COVID-19,

[키워드] 3CL ACE2 angiotensin-converting enzyme 2 Apoptosis binding biological process biological processes cell proliferation component components concept COX2 cytokine Cytoscape database DAVID docking docking result emodin enrichment analysis exploration FIVE IL-17 IL-6 immune system Influenza virus interleukin-6 Intervention Invasion involved KEGG Kyoto Luteolin MAPK mechanism metabolism Necrosis network New Novel coronavirus Occurrence Ontology pathway Pathway enrichment analysis Pathways Pharmacology Pneumonia protease Protein quercetin Regulation Result rutin screened Seven T cell receptor target targets TNF Toll-like receptor treating Treatment was used
[DOI] 10.1155/2022/5536266 PMC 바로가기 [Article Type] Research Article

David versus goliath: ACE2-Fc receptor traps as potential SARS-CoV-2 inhibitors

데이비드 대 골리앗: 잠재적인 SARS-CoV-2 억제제로서의 ACE2-Fc 수용체 트랩

Review

Published on 2022-01-012022-09-11
Journal: mAbs [Category] SARS, 변종,

[키워드] ACE2 ACE2-Fc administration affinity Affinity maturation angiotensin angiotensin-converting enzyme 2 antiviral activity avidity boost catalytic activity catalytic site COVID-19 DAVID Efficacy eliminated ENhance Evolution fusion Hospitalization immunoadhesins IMPROVE inhibitor intrinsic limit monoclonal antibodies monoclonal antibody mutations Neutralizing neutralizing antibody outbreak pandemic pharmacokinetics platform Point mutation point mutations receptor receptor traps. SARS Coronavirus SARS coronavirus 2 SARS-associated betacoronaviruses SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 variant SARS-CoV-2 variants shown Spike protein suggested therapeutic therapeutic agent TRAP Vaccine viral burden viral escape virus spike protein
[DOI] 10.1080/19420862.2022.2057832 PMC 바로가기 [Article Type] Review

Identification of Differentially Expressed Genes in COVID-19 and Integrated Bioinformatics Analysis of Signaling Pathways

COVID-19에서 차별적으로 발현되는 유전자의 식별 및 신호 전달 경로의 통합 생물정보학 분석

Research Article

Published on 2021-12-242022-09-10
Journal: Genetics Research [Category] MERS, SARS, 유전자 메커니즘,

[키워드] Analysis analyzed annotation bioinformatics cause CD69 cellular response chromosome complications coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Cutoff CXCR4 cytokine cytokine production DAVID DEGs Diabetic diabetic complications Diagnosis Differentially expressed genes downregulated enrichment FN1 FoxO FOXP3 gene expression profile Gene ontology GO terms group GSEA help HLA-G hub genes identification IL-17 immune response involved ISG15 KEGG Kyoto leukocyte lung tissue mechanism MMP9 myeloid leukocyte necrotic necrotic cell death nuclear other disease pathway Pathways Pneumonia positive potential mechanisms potential molecular PPI protein-protein interaction RAGE Regulation Research screened selected signaling pathway target Treatment type I interferon upregulated Visualization
[DOI] 10.1155/2021/2728757 PMC 바로가기 [Article Type] Research Article

Exploring Consumer Emotions in Pre-Pandemic and Pandemic Times. A Sentiment Analysis of Perceptions in the Fine-Dining Restaurant Industry in Bucharest, Romania

Article

Published on 2021-12-172022-10-29
Journal: International Journal of Environmental Research an [Category] COVID-19, SARS,

Discussion on “Improving precision and power in randomized trials for COVID-19 treatments using covariate adjustment, for binary, ordinal, and time-to-event outcomes” by David Benkeser, Ivan Diaz, Alex Luedtke, Jodi Segal, Daniel Scharfstein, and Michael Rosenblum

David Benkeser, Ivan Diaz, Alex Luedtke, Jodi Segal, Daniel Scharfstein 및 Michael의 "공변량 조정을 사용하여 이항, 순서 및 이벤트 발생 시간 결과에 대한 COVID-19 치료에 대한 무작위 시험의 정밀도 및 검정력 향상"에 대한 토론 로젠블룸

Comment

Published on 2021-12-012022-09-11
Journal: Biometrics [Category] SARS, 임상,

[키워드] Alex covariate adjustment COVID-19 treatment Daniel DAVID Michael Precision randomized trial Segal
[DOI] 10.1111/biom.13494 PMC 바로가기 [Article Type] Comment

Mental Health of PhD Students at Polish Universities—Before the COVID-19 Outbreak

Article

Published on 2021-11-172022-10-29
Journal: International Journal of Environmental Research an [Category] Coronavirus, MERS, SARS,

[키워드] affected Anxiety COVID-19 DAVID Depression Deterioration disorder dysfunction group identity Insomnia less material men mental health Occurrence PhD students questionnaire reported representation Research statistically stressors student Symptom Symptoms was used women
[DOI] 10.3390/ijerph182212068 PMC 바로가기 [Article Type] Article

24. Longitudinal Assessment of Immune Responses to COVID-19 Vaccines in Solid Organ Transplant Recipients

Oral Abstracts

Published on 2021-11-042022-10-29
Journal: Open Forum Infectious Diseases [Category] COVID-19,

[키워드] 95% CI anti-N IgG anti-RBD anti-S anti-S IgG Anti-S1 antibody assessment baseline black BNT162b2 board cellular response Characteristics Clinical efficacy Cohort collected consultant controls coronavirus disease COVAX COVID COVID-19 COVID-19 vaccine Cutoff DAVID demographics detect domain dose Efficacy enrolled evaluate figure first dose greater healthy healthy control humoral IgG antibodies IgG titer longitudinal magnitude median member mRNA COVID-19 vaccine mRNA vaccine mRNA-1273 natural infection participant Pfizer Phase 3 trials plasma positive positive response prospective cohort study Quanterix Corporation RBD receive recipient recipients reducing Research respond response Result risk SARS-CoV-2 second dose serological response significantly significantly lower Simoa Solid solid organ transplant SOT spike sub-cohort subset T-cell Response table the healthy the SARS-CoV-2 threshold time timepoint timepoints titer Transplant understanding Vaccine vaccine response were excluded were used with COVID-19
[DOI] 10.1093/ofid/ofab466.024 PMC 바로가기 [Article Type] Oral Abstracts

An assessment of treatment, transport, and refusal incidence in a National EMS’s routine work during COVID-19

Research article

Published on 2021-06-012022-10-05
Journal: The American journal of emergency medicine [Category] 치료법,