SARS-CoV-2 nsp14 Exoribonuclease Removes the Natural Antiviral 3′-Deoxy-3′,4′-didehydro-cytidine Nucleotide from RNASARS-CoV-2 nsp14 엑소리보뉴클레아제는 RNA에서 천연 항바이러스성 3'-데옥시-3',4'-디데하이드로-시티딘 뉴클레오타이드를 제거합니다Article Published on 2022-08-162022-09-11 Journal: Viruses [Category] SARS, 변종, 유전자 메커니즘, 치료제, [키워드] 3'-dCTP analogues Antiviral antiviral drug Antiviral effect biochemically caused Chain terminator COVID-19 cytidine 5'-monophosphate ddhCTP Efficacy enzyme ExoN Exoribonuclease facilitate feature global pandemic innate immune response mechanism monophosphate natural natural antiviral non-structural protein nsp14 nucleoside nucleoside analogue nucleotide nucleotide analogues nucleotides produced Proofreading RdRP Remove Replication RNA RNA genome RNA polymerase RNA synthesis RNA-dependent RNA polymerase SARS-CoV-2 susceptible termination the SARS-CoV-2 viral infections Viral RNA [DOI] 10.3390/v14081790 PMC 바로가기 [Article Type] Article
[Biochemical and statistical lessons from the evolution of the SARS-CoV-2 virus: paths for novel antiviral warfare]Review Published on 2020-10-092023-07-06 Journal: Comptes rendus biologies [Category] SARS, [키워드] D614G ddhCTP F1757L L37F Non-homothetic growth TN93 tRNA nucleotidyltransferase. [DOI] 10.5802/crbiol.16 [Article Type] Review