Vitamin D and interferon-γ co-operate to increase the ACE-2 receptor expression in primary cultures of human thyroid cellsArticle Published on 2022-11-012022-11-15 Journal: Journal of Endocrinological Investigation [Category] COVID19(2023년), SARS, 진단, [키워드] ACE-2 ACE-2 receptor angiotensin Cell Cell culture cell membrane cells chain Combination combination treatment Course COVID-19 defend demonstrated experiment expressed expression Host IFN-γ immune defense immunocytochemistry in vitro data interferon-γ material membrane mRNA mRNA level observation primary culture Protein protein level reaction receptor RT-PCR SARS-CoV-2 shown supported Therapeutic benefit Thyrocytes Thyroid tissue treated Treatment up-regulate up-regulated up-regulating Vitamin D were measured would increase [DOI] 10.1007/s40618-022-01857-9 PMC 바로가기
The Integral Membrane Protein ZMPSTE24 Protects Cells from SARS-CoV-2 Spike-Mediated Pseudovirus Infection and Syncytia FormationArticle Published on 2022-10-262022-11-15 Journal: mBio [Category] COVID19(2023년), SARS, 유전자 메커니즘, 치료제, [키워드] acute respiratory syndrome appear assays catalytic caused Cell cell-cell fusion cell-cell fusion assay cells cellular cellular component cellular membrane contribute coronavirus coronavirus SARS-CoV-2 Coronaviruses COVID-19 COVID-19 pandemic dead defend Defense Efficiency ENhance entry of SARS-CoV-2 examined Formation genetic knockout global public health host cell membranes IFITM IFITMs in viral include Infection inhibiting inhibitory activity innate immune innate immune response Integral interact Interaction interfere intrinsic knockdown lentivirus maturation mechanism membrane membrane protein MHV mouse hepatitis virus nuclear overexpression pandemic Plaque assay precursor prelamin A Prevent protease Proteases PROTECT Protective protective role Protein proteolytic proteolytic activity reduce required restriction factor restriction factor. SARS-CoV-2 SARS-CoV-2 pseudovirus infection shown spike Therapeutic benefit transmembrane protein viral infection viral infections virus virus entry viruses wild-type ZMPSTE24 [DOI] 10.1128/mbio.02543-22 PMC 바로가기
Protective neutralizing epitopes in SARS-CoV-2Article Published on 2022-09-012022-11-15 Journal: Immunological reviews [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] antibody Antibody therapeutics caused cell entry coronavirus COVID-19 pandemic defend elicited epitope epitope conservation etiological agent evade Health Hospitalization host cell immune defense immune system Immunity Infection molecular neutralizing antibody neutralizing epitope new virus Protective provided SARS-CoV-2 severe disease strong immune response Structure Transmissibility vaccination Vaccine variant variants viral infection virus [DOI] 10.1111/imr.13084 PMC 바로가기
Adaptive Immune Responses and Immunity to SARS-CoV-2SARS-CoV-2에 대한 적응 면역 반응 및 면역Review Published on 2022-05-042022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 변종, [키워드] activated Activation adaptive Adaptive immune response adaptive immune responses Adaptive immunity Antigen antigen-presenting cell antigen-presenting cells B cell B cell receptors B.1.1.529 B.1.617.2 backbone biological interaction Blood Blood donors Breakthrough infection breakthrough infections cellular Cellular immune response cellular immunity cellular response Clonality competence COVID-19 COVID-19 pandemic defend Defense defense mechanism Delta demonstrated heparinized blood Host humoral Humoral response humoral responses IgA immune immune reaction immune responses Immunity Immunocompromised Immunocompromised patient Immunocompromised patients Immunological memory immunology induce Infection interferon gamma interferon gamma. Interferon-gamma knowledge long-lasting maturation mechanism memory mucosal nasal omicron pandemic peptides Research response SARS-CoV SARS-CoV-2 SARS-CoV-2 pandemic SARS-CoV-2 T cell memory shown stimulated T cell T cell memory T cells the SARS-CoV-2 translate undetectable Vaccine Vaccines variants variants of concern Viral antigen viral particle virus [DOI] 10.3389/fimmu.2022.848582 PMC 바로가기 [Article Type] Review
Applied behavioral economics and public health policies: Historical precedence and translational promiseResearch article Published on 2022-05-012022-10-05 Journal: Behavioural Processes [Category] 비임상, [키워드] advance alcohol approach baseline behavioral economics COVID-19 vaccine decrement defend Demand Discounting effort example experimental analysis implication Preventive medicine psychometric properties public health translational widespread [DOI] 10.1016/j.beproc.2022.104640 [Article Type] Research article
Misinformation, believability, and vaccine acceptance over 40 countries: Takeaways from the initial phase of the COVID-19 infodemicResearch Article Published on 2022-02-092022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, [키워드] association country Course COVID-19 COVID-19 pandemic Critical defend GDP implication individual infodemic information initial misinformation pandemic platform Prevalence Public health intervention Region Research response risk social distancing Spread susceptibility susceptible vaccination Vaccine wearing masks [DOI] 10.1371/journal.pone.0263381 PMC 바로가기 [Article Type] Research Article
Trends in Violent Penetrating Injuries During the First Year of the COVID-19 PandemicResearch Published on 2022-02-082022-10-29 Journal: JAMA Network Open [Category] Coronavirus, COVID19(2023년), MERS, SARS, [키워드] age analyzed Black patient Boston center Characteristics Community contributed COVID-19 COVID-19 pandemic cross-sectional decrease defend demographics effort England evaluated finding Health Hispanic Hispanic patient hospital Importance incidence increase in Injury Intervention male Massachusett measure median men mitigate New objective pandemic participant Patient Penetrating per day Point presenting Prevalence Primary outcome Public Racial reduce Relevance Result Retrospective cross-sectional study setting significant increase spread of COVID-19 the epidemic trauma treated trend was performed White patient women Year [DOI] 10.1001/jamanetworkopen.2021.45708 PMC 바로가기 [Article Type] Research
COVID-19 Compulsory Vaccination: Legal and Bioethical ControversiesMedicine Published on 2022-02-022022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] age approved Autonomy category compulsory vaccination Consent country COVID-19 COVID-19 pandemic COVID-19 vaccination COVID-19 vaccine defend effective European form Greece Health healthcare professionals individuals Indonesia International Italian Italy mandatory obligations offer pandemic provided public health state subject Treatment union vaccination Vaccinations [DOI] 10.3389/fmed.2022.821522 PMC 바로가기 [Article Type] Medicine
Epidemiological Indicators of SARS-CoV-2 (COVID-19) and Vaccination Effectiveness on the Report of Positive Cases in the Colombian ArmyMedicine Published on 2021-12-092022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] addition attack rate blocked Case fatality rate CFR Colombia condition Control COVID-19 Critical decrease defend Effectiveness epidemiological Epidemiology facilitate Fatality rate geographical distribution health system healthy Indicator Migration military forces molecular and antigen diagnostic tests mortality rate National pandemic positive patient report reported SARS-CoV-2 shown Spread Surveillance total population Transmission used to evaluate vaccination virus [DOI] 10.3389/fmed.2021.791761 PMC 바로가기 [Article Type] Medicine
Anaesthetic challenges in a child with perforated appendicitis and COVID-19 Co-Infection: A case reportCase Report Published on 2021-10-122022-10-28 Journal: Annals of Medicine and Surgery [Category] COVID-19, [키워드] Perforated appendicitis Affect appendicectomy Appendicitis Care Case report caused challenge Child children children with COVID-19 Co-infection coronavirus disease COVID-19 COVID-19 infection COVID-19 pandemic cross Cross-infection defend detrimental effect equipment Good handling HCW healthcare worker hospital infected with COVID-19 Infection initial management measure multi operating theatre pandemic parent Patient patients patients with COVID-19 Personal protective equipment positive PPE Prevent problem Protective receive resource risk routine care Safe Spread spread of COVID-19 surgical the patient upper respiratory tract wearing with COVID-19 [DOI] 10.1016/j.amsu.2021.102931 PMC 바로가기 [Article Type] Case Report