A computational study of metal-organic frameworks (MOFs) as potential nanostructures to combat SARS-CoV-2Article Published on 2022-09-202022-11-15 Journal: Scientific Reports [Category] SARS, 치료제, [키워드] ACE acute respiratory syndrome angiotensin-converting enzyme 2 antibody antiviral drug binding biological molecule carrier coronavirus COVID-19 Critical deformation determine drug host cells inhibitor Interaction investigated M pro MOF molecular nanobody non-structural protein protease Protein receptor S protein SARS-CoV-2 secondary structure Spike protein surface protein tested Vaccine virus replication [DOI] 10.1038/s41598-022-19845-7 PMC 바로가기
Echocardiographic assessment of COVID19 sequelae in survivors with elevated cardiac biomarkers심장 바이오마커가 상승된 생존자의 COVID19 후유증에 대한 심장초음파 평가Article Published on 2022-08-012022-09-11 Journal: International journal of cardiology [Category] 바이오마커, [키워드] abnormality Admission age analyzed baseline characteristics Biomarker cardiovascular cardiovascular disease cardiovascular diseases cardiovascular event Control COVID COVID19 D-dimer dead Deep vein Deep vein thrombosis deformation determine discharge during admission Echocardiogram echocardiography elevated Follow-up group groups hs-TNI Implications Infection intensive care LVEF management median Mild Myocardial no difference no differences normal range occurred parameters Patient Patient management patients Prevalence Prognosis prognostic screening program Sequelae significantly Support survivor tertiary referral hospital thrombosis were excluded [DOI] 10.1016/j.ijcard.2022.04.070 PMC 바로가기 [Article Type] Article
Virucidal Properties of Photocatalytic Coating on Glass against a Model Human Coronavirus모델 인간 코로나바이러스에 대한 유리의 광촉매 코팅의 바이러스 살균 특성Article Published on 2022-06-292022-09-11 Journal: Microbiology Spectrum [Category] COVID19(2023년), SARS, 치료제, [키워드] added aerosol alteration Antiviral antiviral activity can not coated with coating construction Contact Contagion Contamination coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 damaged deformation Disruption electron microscopy element Epidemiology Evidence evidence of exposure to glass human coronavirus human coronaviruses in-depth analysis inactivation increase infectious investigated Kinetics knowledge Masks Microscopy mitigate Model morphologically pandemic performed Photocatalysis photocatalytic coating physical physical barrier property Protective protective effect Protective effects reduced reducing Research SARS-CoV-2 Spread suggested surface titanium titanium dioxide Transmission viral envelope virion virions virucidal virucidal activity virus virus spread virus titer viruses [DOI] 10.1128/spectrum.00269-22 PMC 바로가기 [Article Type] Article
Mechanical control of innate immune responses against viral infection revealed in a human lung alveolus chipArticle Published on 2022-04-082022-10-04 Journal: Nature Communications [Category] 바이오마커, 변종, 치료제, [키워드] activating Activation Antimicrobial responses Apoptosis attenuate cascade Cell circulating contribute cytokine deformation disease endothelial cells epithelial facilitate H3N2 infection host innate immunity host response human lung immune cells induce Inflammation Inflammatory response Influenza influenza infection inhibitor innate immune response Innate immunity life-threatening lung Lung inflammation Mechanical pandemic Patient physical potential therapeutic target Protective RAGE receptor recruitment reveal Signaling suppress target therapeutic intervention tissue engineering TRPV4 viral burden viral infection viral replication virus [DOI] 10.1038/s41467-022-29562-4 PMC 바로가기 [Article Type] Article
Cardiac involvement in patients recovered from COVID-19 identified using left ventricular longitudinal strain좌심실 세로 변형을 사용하여 확인된 COVID-19에서 회복된 환자의 심장 침범Article Published on 2022-03-012022-09-11 Journal: Journal of echocardiography [Category] SARS, 치료기술, [키워드] abnormality acute phase both groups cardiac control group coronavirus disease COVID-19 COVID-19 patient COVID-19 patients deformation demographic detect diagnostic echocardiographic parameter echocardiographic parameters echocardiography edema evaluate GLS healthy individuals hospitalized patients in both groups left LVEF median myocardial damage Myocardial dysfunction myocardial involvement Patient question recovered reduced reduction in strain the disease ventricular ventricular ejection was performed [DOI] 10.1007/s12574-021-00555-4 PMC 바로가기 [Article Type] Article
Photothermal inactivation of universal viral particles by localized surface plasmon resonance mediated heating filter membrane국소화 된 표면 플라즈몬 공명 매개 가열 필터 멤브레인에 의한 보편적 바이러스 입자의 광열 불 활성화Article Published on 2022-02-022022-09-01 Journal: Scientific Reports [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] 50% tissue culture infective dose cells Chain Reaction coated components Crystal violet Culture deformation denaturation dose effective gold H1Npdm09 HFM inactivation infectious sample infectious samples infective Infective dose Influenza virus irradiation Mardin membrane membrane protein Membrane proteins Nanoparticles Nanophotonics and plasmonics Natural hazards polymerase chain polymerase chain reaction provide qRT-PCR Quality control Quantitative reduce reduction reduction in reverse transcription room temperature SARS-CoV-2 staining surface plasmon surface plasmon resonance surface temperature TCID temperature tissue tissue culture Viral viral gene viral genes viral infectivity viral particle virus titer was reduced [DOI] 10.1038/s41598-022-05738-2 PMC 바로가기 [Article Type] Article
Frequent Constriction-Like Echocardiographic Findings in Elite Athletes Following Mild COVID-19: A Propensity Score-Matched AnalysisCardiovascular Medicine Published on 2022-01-052022-10-31 Journal: Frontiers in Cardiovascular Medicine [Category] COVID-19, [키워드] 3D echocardiography athlete athlete's heart calculated change characteristic Cohort comparable constrictive pericaditis control group COVID-19 deformation driven by echocardiographic Effect Ejection fraction Elite enrolled feature female finding functional GLS healthy Infection left less LVEF Morphological not differ propensity score matching quantified SARS-CoV-2 selected septal significantly higher significantly lower speckle-tracking analysis Symptom ventricular Volume with COVID-19 [DOI] 10.3389/fcvm.2021.760651 PMC 바로가기 [Article Type] Cardiovascular Medicine
Global Longitudinal Strain Reduction in the Absence of Clinical Cardiac Symptoms in Multisystem Inflammatory Syndrome in Children Associated with COVID-19: A Case SeriesCOVID-19와 관련된 어린이의 다기관 염증 증후군에서 임상적 심장 증상이 없는 경우 전체 종 방향 변형 감소: 사례 시리즈Article Published on 2022-01-012022-09-11 Journal: Pediatric cardiology [Category] SARS, 치료기술, [키워드] cardiac cardiac function Cardiac magnetic resonance imaging Cardiogenic shock changes in children clinical COVID-19 COVID-19 infection deformation detect echocardiography Effect Ejection fraction Follow-up Global longitudinal strain GLS Hypotension Inflammatory longitudinal Mild multisystem inflammatory syndrome in children myocardial injury myocarditis Patient pediatric reduced Research Sery Shock strain Stress Symptom Symptoms syndrome systemic inflammation systemic inflammatory term tissue variety ventricular ventricular ejection [DOI] 10.1007/s00246-021-02712-z PMC 바로가기 [Article Type] Article
Lung segmentation and automatic detection of COVID-19 using radiomic features from chest CT imagesResearch article Published on 2021-11-012022-10-05 Journal: Sensors (Basel, Switzerland) [Category] 치료기술, [키워드] 3D V-Net adopted analyzed approach assist AUC automatic detection Chest CT Chest CT image Chest CT images Clinical use community-acquired pneumonia COVID-19 COVID-19 diagnosis COVID-19 infection deep learning deformation demonstrated detect develop diagnosis of COVID-19 Dice Experimental result feature Features healthy control independent Infection knowledge lung Lung infection operators pulmonary parenchyma Pulmonary parenchyma segmentation radiologist Region sensitivity similarity specificity statistical model statistically significant with COVID-19 [DOI] 10.1016/j.patcog.2021.108071 [Article Type] Research article
Enteric Coronavirus Infection and Treatment Modeled With an Immunocompetent Human Intestine-On-A-ChipPharmacology Published on 2021-10-252022-10-31 Journal: Frontiers in Pharmacology [Category] COVID-19, [키워드] ACE2 protein ACE2 receptor Anti-inflammatory Anti-viral approved cellular circulating coronavirus Coronavirus infection Coronaviruses COVID-19 COVID19 patients Culture cytokine production cytokine secretion deformation demonstrated drug Effect effective Endothelium enteric Gastrointestinal symptom Host Human human gastrointestinal tract infect cells Infection Inflammation Inflammatory Inflammatory response inhibited intestinal intestinal epithelial cell intestinal epithelium intestine intestine chip mononuclear cell nafamostat NL63 Organoid organs on chip pathology Patient PBMCs Peripheral blood Protease inhibitor recruitment reduction in Remdesevir Remdesivir SARS-CoV-2 SARS–CoV–2 These data Vascular endothelium viral entry Viral load Viral protein [DOI] 10.3389/fphar.2021.718484 PMC 바로가기 [Article Type] Pharmacology