DEGs
[용어속성] Term
Identification of the Hub Genes and the Signaling Pathways in Human iPSC-Cardiomyocytes Infected by SARS-CoV-2
Article
[키워드] Analysis
applied
Bioinformatics analysis
biological process
Biomarker
Brain
caused
component
Cytoscape software
database
dataset
DEGs
differentially expressed gene
direct infection
down-regulated gene
enrichment analysis
function
Gene Expression Omnibus
gene expression profile
Gene ontology
Genes
GEO
GraphPad Prism software
High-throughput sequencing
hub genes
Human
Human iPSC-cardiomyocytes
identification
infected with SARS-CoV-2
intestine
KEGG
kidney
Kyoto
Ligand
liver
Lung injury
mechanisms
myocardial injury
organ
pathway
Pathways
PPI
PPI network
protein-protein interaction
R software
receptor
Research
respiratory
respiratory symptom
SARS-CoV-2
screened
sequencing data
signaling pathway
single-stranded RNA virus
statistical analysis
statistically significant
TNF signaling
Type
type I interferon
up-regulated
was obtained
was performed
website
[DOI] 10.1007/s10528-022-10206-7 PMC 바로가기
[DOI] 10.1007/s10528-022-10206-7 PMC 바로가기
A Bioinformatic Approach Based on Systems Biology to Determine the Effects of SARS-CoV-2 Infection in Patients with Hypertrophic Cardiomyopathy
Article
[키워드] acute respiratory syndrome
Affect
Analysis
Bioinformatic
Biology
Biomarker
Cardiomyopathy
cardiovascular system
Combination
conducted
coronavirus
coronavirus disease
COVID-19
COVID-19 progression
datasets
DEGs
differentially expressed gene
disorder
drug
drug candidates
Effect
functional
Gene Expression Omnibus
Genes
Genetic
GSE147507
identify
individual
knowledge
Lungs
microRNA
mortality rate;
ontology terms
other organs
patients with COVID-19
protein-protein interaction
Proteins
Research
RNA
SARS-CoV-2
Sequencing
shared pathway
shown
statistical
Support
System
therapy
transcription factors
transcriptomic
while
[DOI] 10.1155/2022/5337380 PMC 바로가기
[DOI] 10.1155/2022/5337380 PMC 바로가기
Identification of the effects of COVID-19 on patients with pulmonary fibrosis and lung cancer: a bioinformatics analysis and literature review
Article
[키워드] applied
approach
bioinformatics
Bioinformatics analysis
Biomarker
Cancer
Colorectal cancer
complications of COVID-19
core gene
Coronavirus disease 2019
COVID-19
COVID-19 complication
DEGs
Diseases
drug
drug candidates
Effect
effective
feature
Health
highest
identification
identify
idiopathic
IPF
literature review
lung
lung cancer
Lung fibrosis
Metastasis
molecular
morbidity and mortality
Mortality
pathway
Patient
patients
positive
pulmonary fibrosis
reducing
risk
risk factor
significantly
Spread
Systems biology
the epidemic
the SARS-CoV-2 virus
Transcriptome
treating COVID-19
Treatment
[DOI] 10.1038/s41598-022-20040-x PMC 바로가기
[DOI] 10.1038/s41598-022-20040-x PMC 바로가기
Bioinformatics and systems-biology analysis to determine the effects of Coronavirus disease 2019 on patients with allergic asthma
Article
[키워드] addition
allergic
Allergic asthma
Analysis
approach
association
Asthma
asthmatic
bioinformatics
Biomarker
can be used
candidate drug
candidate drugs
Comorbidity
conducted
coronavirus disease
Coronavirus disease 2019
COVID-19
COVID-19 progression
COVID-19 symptom
Critical
dataset
datasets
DEGs
determine
differentially expressed gene
disease
disease biomarker
drug
Effect
elevated
Evidence
expression level
Gene ontology
Genes
health systems
hub gene
identify
IL-13
IL-5
Increasing
Interaction
interactions
lung
mechanism
molecular
molecular mechanism
MUC5AC
murine
murine model
pandemic
pathway
Pathway analysis
Patient
patients with COVID-19
phenotype
potential molecular
risk factor
severity
shared pathways
statistical
Systems biology
systems-biology.
Transcription
[DOI] 10.3389/fimmu.2022.988479 PMC 바로가기
[DOI] 10.3389/fimmu.2022.988479 PMC 바로가기
Comparison of Intracellular Transcriptional Response of NHBE Cells to Infection with SARS-CoV-2 Washington and New York Strains
Article
Published on
Journal: Frontiers in Cellular and Infection Microbiology [Category] SARS, 유전자 메커니즘, 치료기술,
Journal: Frontiers in Cellular and Infection Microbiology [Category] SARS, 유전자 메커니즘, 치료기술,
[키워드] 24 hour
acute respiratory syndrome
affected
analyzed
bioinformatics
caused
Cell
cellular
coronavirus
COVID-19
D614G mutation
Data mining
death
DEGs
different time point
differentially expressed gene
dysregulated
Effect
epithelial
experiment
Gene ontology
Genome
global pandemic
GO terms
Host
host cells
host response
Host transcriptional response
host-virus
hpi
identify
immune
IMPROVE
include
Infection
infections
inhibited
Intracellular
mechanism
Mutation
New York
NHBE
pathway
Pathways
Patient
positive
Post-infection
reported
response
resulting
RNA sequencing data
SARS-CoV-2
SARS-CoV-2 isolate
severe disease
shown
Signaling
signaling pathways
similarity
stability
strain
Strains
These data
transcript
translation
viral isolate
viral spike protein
Virology
virus
virus replication
Washington
while
Wuhan, China
[DOI] 10.3389/fcimb.2022.1009328 PMC 바로가기
[DOI] 10.3389/fcimb.2022.1009328 PMC 바로가기
IFI44 is an immune evasion biomarker for SARS-CoV-2 and Staphylococcus aureus infection in patients with RA
Article
[키워드] 1,25-dihydroxy vitamin D3
activated
acute respiratory syndrome
analyses
Analysis
applied
autoimmune conditions
Bacteremia
Bacterial
Bacterial infection
Bacterial infections
Bioinformatics analysis
Biomarker
caused
Cell
cell membrane
CIBERSORT
conducted
coronavirus
COVID-19
Cytoscape
database
dataset
datasets
DEGs
dendritic cell
dendritic cells
dendritic cells.
differentially expressed
differentially expressed gene
disease
DNA
drug target
Effectiveness
examined
expression
FIVE
functional enrichment
Functional enrichment analysis
GBP1
gene network
GeneMANIA
Genes
global pandemic
HERC5
humans
identify
Ifi44
IFI44L
IFIT3
IFIT5
IFN signaling
IFN signaling pathway
IFN-α/β
Immune cell infiltration
immune cells
Immune escape
immune evasion
immune system
Immunological response
Infection
infections
infiltration
Intersection
ISG15
KEGG
mechanism
miRNA
molecular mechanism
molecular target
NLR
OAS1
oxidative phosphorylation
pathogenic bacteria
pathway
Patient
platform
positive correlation
PPI network
prevalent
proliferation
promote
regulate
Regulation
Rheumatoid
rheumatoid arthritis
risk factor
ROC curves
RSAD2
Rtp4
SARS-CoV-2
SARS-COV-2 infection
severe coronavirus disease
signaling pathway
Staphylococcus
Staphylococcus aureus
target
the SARS-CoV-2
therapeutic
viral infection
viral replication
virus
were used
YY1
[DOI] 10.3389/fimmu.2022.1013322 PMC 바로가기
[DOI] 10.3389/fimmu.2022.1013322 PMC 바로가기
Presepsin Predicts Severity and Secondary Bacterial Infection in COVID-19 by Bioinformatics Analysis
Article
[키워드] acute respiratory disease
Analysis
AUC
biological processes
caused
CD14
cellular components
Coronavirus pneumonia
COVID-19
COVID-19 patient
Critical
datasets
deaths
DEGs
Diagnosis
diagnostic value
differentially expressed gene
downregulated
enrichment analysis
expression
function
Gene ontology
KEGG
Kyoto
limit
majority
moderate
molecular function
nonsurvivor
novel
novel coronavirus SARS-CoV-2
Pathway enrichment analysis
PPI
predict
Prognosis
protein-protein interaction
screened
secondary
secondary bacterial infection
selected
severe COVID-19
severe COVID-19 patient
severity
significantly
significantly higher
significantly increased
survivor
Treatment
upregulated
utility
was performed
[DOI] 10.1155/2022/9914927 PMC 바로가기
[DOI] 10.1155/2022/9914927 PMC 바로가기
Deciphering SARS CoV-2-associated pathways from RNA sequencing data of COVID-19-infected A549 cells and potential therapeutics using in silico methods
Article
[키워드] A549 cell
activated
Activation
acute respiratory syndrome
addition
Analysis
Atypical
candidate
caused
characterized
CLC
complications
CoV
COVID
COVID-19
COVID-19 infection
cytokine
deaths
DEGs
Determining
differentially expressed gene
disease
drug
effective
experimental validation
Gene Expression Omnibus
gene signatures
Genomics
GEO
GSE147507
human-to-human transmission
identify
IFNβ
IL-17
IL-1β
Illumina
in silico
In silico method
influenza A
Interaction
interferon beta
interferon regulatory factor
IRF3
IRF9
JQ1
knowledge
mechanism
Methylprednisolone
mock-treated
pathology
pathway
Pneumonia
Prednisolone
Quality control
receptors
RNA
RNA sequencing
RNA sequencing data
SARS CoV-2
signaling pathway
signaling pathways
small molecule
STAT2
the Coronaviridae
the disease
therapy
Transcription
Treatment
underlying disease
upstream
Viral protein
virus infection
was used
with COVID-19
Wuhan, China
[DOI] 10.1097/MD.0000000000029554 PMC 바로가기
[DOI] 10.1097/MD.0000000000029554 PMC 바로가기
Discovering common pathogenetic processes between COVID-19 and sepsis by bioinformatics and system biology approach
Article
[키워드] acute respiratory syndrome
addition
Analysis
approach
bioinformatics
Biomarker
Blood
caused
clinical manifestations
Clinical practice
Coagulopathy
Corona
Coronavirus-2
COVID-19
Critically ill
Critically ill patient
Cytokine storm
database
DEGs
demonstrated
diagnostic
differentially expressed
differentially expressed gene
differentially expressed gene (DEG)
disease
drug molecule
enrichment analysis
functional
functional enrichment
Gene Expression Omnibus
gene expression profile
Gene ontology
gene regulatory network
genetic link
genetic mechanism
GEO
high mortality rate
hub gene
hypercoagulable
Inflammatory response
Interaction
ITGAM
molecular docking
molecular mechanism
multiple organ dysfunction
neutrophil dysfunction
pandemic
Pathogenesis
pathogenesis of COVID-19
pathway
potential therapeutic agents
progesterone
protein-protein interaction
Protein–protein interaction
protein–protein interaction (PPI)
receptor
Regulatory
Research
respiratory infectious disease
resulting
risk
SARS-CoV-2
screened
Sepsis
sepsis patient
Septic shock
severe COVID-19
signaling pathway
similarity
Spread
syndrome
System biology
Systems biology
Treatment
were used
with COVID-19
[DOI] 10.3389/fimmu.2022.975848 PMC 바로가기
[DOI] 10.3389/fimmu.2022.975848 PMC 바로가기