Molecular dynamics simulations explore effects of electric field orientations on spike proteins of SARS-CoV-2 virions분자 역학 시뮬레이션은 SARS-CoV-2 비리온의 스파이크 단백질에 대한 전기장 방향의 영향을 탐구합니다.Article Published on 2022-07-292022-09-11 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 변종, [키워드] acute respiratory disease acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 binding caused coronavirus COVID-19 Critical denaturing direction Disruption domain Effect effective emergence entry of SARS-CoV-2 Health host cell host cells humans membrane fusion Mild molecular dynamics Molecular dynamics simulation mutants Non-invasive pandemic Protein Protein binding receptor Research Respiratory illness responsible S protein SARS-CoV-2 SARS-CoV-2 spike glycoprotein SARS-CoV-2 virion severe acute respiratory syndrome Coronavirus spike glycoprotein Spike protein Spread the S protein the SARS-CoV-2 viral entry viral membrane virus [DOI] 10.1038/s41598-022-17009-1 PMC 바로가기 [Article Type] Article
Validation of a Saliva-Based Test for the Molecular Diagnosis of SARS-CoV-2 InfectionResearch Article Published on 2022-01-072022-10-31 Journal: Disease Markers [Category] COVID-19, SARS, [키워드] 95% CI asymptomatic subject clinical sensitivity clinicians and researcher collected Collection Concordance conducted controls denaturing determine Diagnosis diagnostic effective enrolled gold standard IMPROVE Infection infective inhibiting internal Laboratory test lack molecular nasopharyngeal Negative predictive value NP swab NP swabs NPV offer pandemic Patient Population screening Positive predictive value PPV reduce Result risk RT-PCR RT-PCR assay saline solution Saliva saliva sample saliva samples SARS-CoV-2 sensitivity specificity Swab Test tested the SARS-CoV-2 Transport validation viral genome virus was performed [DOI] 10.1155/2022/6478434 PMC 바로가기 [Article Type] Research Article
High-Yield Production of Receptor Binding Domain of SARS-CoV-2 Linked to Bacterial Flagellin in Plants Using Self-Replicating Viral Vector pEffArticle Published on 2021-12-062022-10-28 Journal: Plants [Category] COVID-19, [키워드] conditions coronavirus COVID-19 COVID-19 pandemic cytosol denaturing dialysis expressed expression flagellin fraction fused fusion protein Genome insoluble intranasal mucosal Ni-NTA Nicotiana benthamiana plant plants Production Protein purification purified RBD reached Receptor binding domain recombinant vaccine remained reported required Salmonella Typhimurium SARS-CoV-2 SARS-CoV-2 spike glycoprotein tissue Vaccine vector virus [DOI] 10.3390/plants10122682 PMC 바로가기 [Article Type] Article
Effect of ambient temperature on respiratory tract cells exposed to SARS-CoV-2 viral mimicking nanospheres-An experimental studySARS-CoV-2 바이러스 모방 나노스피어에 노출된 호흡기 세포에 대한 주변 온도의 영향-실험 연구Article Published on 2021-01-282022-09-12 Journal: Biointerphases [Category] 진단, [키워드] ACE-2 ACE-2 receptor acute respiratory syndrome airway epithelial cell ambient angiotensin-converting enzyme 2 binding bovine Calu-3 caused change coated with Community coronavirus country denaturing Effect fibroblast cell fluctuation had no Host host cell incubated indicated infect Infection Infectious disease Interaction lung epithelia mimicking modulated nonspecific Novel coronavirus occurred pandemic Polymer Protein RBD reached reported respiratory tract respiratory tract cell S protein S-RBD SARS-CoV-1 SARS-CoV-2 SARS-CoV-2 viral seasonal serum Spread stability surface receptor temperature the S protein the SARS-CoV-2 Transmission Viral transmission virus [DOI] 10.1116/6.0000743 PMC 바로가기 [Article Type] Article
Antiviral Activity of Reagents in Mouth Rinses against SARS-CoV-2SARS-CoV-2에 대한 구강 세정제의 항바이러스 활성Review Published on 2020-10-222022-09-10 Journal: Journal of Dental Research [Category] MERS, 치료제, [키워드] activity aerodigestive tract Antiviral antiviral property capsid Cetylpyridinium cetylpyridinium chloride chlorhexidine chloride Clinical research Clinical studies clinical trial contribute COVID-19 COVID-19 pandemic Critical cyclodextrin denaturing enveloped virus essential oils Evidence examined hydrogen hydrogen peroxide IMPROVE indicate Iodine knowledge leads membrane mouth mouthwashes oral oral cavity pathogenicity povidone povidone-iodine Proteins protocol reagent reagents reduce reducing Research Saliva salivary SARS-CoV-2 transmission of SARS-CoV-2 Viral Viral load virus while [DOI] 10.1177/0022034520967933 PMC 바로가기 [Article Type] Review