Optimizing Nanosuspension Drug Release and Wound Healing Using a Design of Experiments Approach: Improving the Drug Delivery Potential of NDH-4338 for Treating Chemical BurnsArticle Published on 2024-03-272024-09-05 Journal: Pharmaceutics [Category] update2024, [키워드] design of experiments nanosuspension nitrogen mustard [DOI] 10.3390/pharmaceutics16040471 PMC 바로가기 [Article Type] Article
Limitations of randomized, controlled, double-blinded studies in determining safety and effectiveness of treatmentsRandomized Controlled Trial Published on 2022-06-012023-07-09 Journal: Current medical research and opinion [Category] COVID19(2023년), [키워드] Clinical research COVID-19 design of experiments Medical statistics Therapeutics [DOI] 10.1080/03007995.2022.2073121 [Article Type] Randomized Controlled Trial
Rational Design of CRISPR/Cas12a-RPA Based One-Pot COVID-19 Detection with Design of Experiments실험 계획을 통한 CRISPR/Cas12a-RPA 기반 One-Pot COVID-19 탐지의 합리적 설계Article Published on 2022-04-152022-09-11 Journal: ACS synthetic biology [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] accelerate addition amplification applied approach benefit buffer complex component components condition COVID-19 COVID-19 pandemic CRISPR CRISPR/Cas12a critical impact definitive screening design demonstrated design of experiments detection Detection sensitivity diagnostic Diagnostic method diagnostics DNA DNA sequence DoE Effect effective experiment Factor full-length SARS-CoV-2 Genome highlight isothermal molecular Molecular diagnosis N gene one-pot COVID-19 testing optimization polymerase reaction reaction optimization Reactions recombinase polymerase amplification recombinase polymerase amplification (RPA). reverse transcription RNA RNase RNase inhibitor robust RPA RT-qPCR sensitivity significant effect significantly simple statistical variables [DOI] 10.1021/acssynbio.1c00617 PMC 바로가기 [Article Type] Article
COVID-19 vaccine preferences in IndiaArticle Published on 2022-04-012023-07-08 Journal: Vaccine [Category] COVID19(2023년), [키워드] Consumer economics: empirical analysis COVID-19 design of experiments Vaccines [DOI] 10.1016/j.vaccine.2022.02.077 PMC 바로가기
Optimization, Production, Purification and Characterization of HIV-1 GAG-Based Virus-like Particles Functionalized with SARS-CoV-2Article Published on 2022-02-072022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] acute respiratory syndrome approach bioprocess cGMP Characteristics characterization co-expression coronavirus coronavirus spike protein COVID-19 design of experiments different disease DoE downstream Downstream process ENhance experiment expression Gag generate genetic material good manufacturing practice HEK293 HIV-1 immunogenic membrane protein methodology optimization Particle performed platform Production Protein purification robust Safe SARS-CoV-2 SARS-CoV-2 VLP Structure transient transfection vaccine candidate Vaccine development variants virus VLP VLP vaccines VLPs wild-type [DOI] 10.3390/vaccines10020250 PMC 바로가기 [Article Type] Article
Copy number variants and fixed duplications among 198 rhesus macaques ( Macaca mulatta )198마리의 붉은털 원숭이( Macaca mulatta ) 사이의 복제 수 변종 및 수정된 중복Research Article Published on 2020-05-112022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] assumption Biomedical research chromosome composed concerning conducted copy copy number copy number variant Copy number variants dataset design of experiments disease risk distribution duplication duplications event Evolution experiment fixed focus functional consequences genetic difference genetic differences Genetic variation Genome genomes genomic genomic region high resolution High-resolution highlight human disease humans individual individuals inter-individual knowledge large sample Old World monkey Old World monkeys one individual organism Organisms orthologs performed Phylogenetic relationship profile reference genome Region regions representing Research rhesus rhesus macaque rhesus macaques sequence similarity species target gene Target genes variable regions Variation [DOI] 10.1371/journal.pgen.1008742 PMC 바로가기 [Article Type] Research Article
Optimization of tetanus toxoid ammonium sulfate precipitation process using response surface methodology반응표면법을 이용한 파상풍 톡소이드 황산암모늄 침전 공정 최적화journal-article Published on 2016-10-022024-07-30 Journal: Preparative Biochemistry & Biotechnology [Category] 파상풍, [키워드] Ammonium sulfate precipitation design of experiments mass spectrometry radial immunodiffusion tetanus toxoid tetanus vaccine [DOI] 10.1080/10826068.2015.1135452 [Article Type] journal-article
Capsular polysaccharide production by Streptococcus pneumoniae serotype 1: from strain selection to fed-batch cultivation스트렙토코쿠스 뉴모니아에 세로타입 1에 의한 캡슐 다당체 생산: 균주 선택에서 배지 공급 배양까지journal-article Published on 2015-12-012024-08-04 Journal: Applied Microbiology and Biotechnology [Category] 폐렴구균 감염증, [키워드] Capsular polysaccharide production design of experiments Fed-batch cultivation Peptone selection pneumococcus Strain screening. [DOI] 10.1007/s00253-015-6928-z [Article Type] journal-article
Design and optimization of a chromatographic purification process for Streptococcus pneumoniae serotype 23F capsular polysaccharide by a Design of Experiments approach스트렙토코쿠스 뉴모니아에 대한 실험 설계 접근 방식을 통한 23F 혈청형 캡슐 다당류의 크로마토그래픽 정제 공정 설계 및 최적화journal-article Published on 2014-06-012024-08-04 Journal: Journal of dietary supplements [Category] 폐렴구균 감염증, [키워드] capsular polysaccharide Chromatography purification design of experiments pneumococcal vaccine [DOI] 10.1016/j.chroma.2014.04.096 [Article Type] journal-article