detrimental effect – Communicable Diseases Research

Vaccination in patients with kidney failure: lessons from COVID-19

Reviews

Published on 2022-08-012022-10-05
Journal: Nature reviews. Nephrology [Category] SARS, 진단, 치료기술, 치료법, 치료제,

Plasmacytoid dendritic cells during COVID-19: Ally or adversary?

COVID-19 동안 형질세포양 수지상 세포: 동맹 또는 적

Review

Published on 2022-07-262022-09-11
Journal: Cell Reports [Category] COVID19(2023년), SARS, 변종, 치료제,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 airways Alpha Antiviral antiviral responses antivirals causative agent Cell cellular contribute coronavirus COVID-19 COVID-19 disease CP: Immunology CP: Microbiology dendritic cell dendritic cells detrimental effect detrimental effects disease IFN IFNs IFNα immune system immunology infections Inflammation Interferon alpha Microbiology outcome pDC pDCs plasmacytoid dendritic cells SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome Coronavirus subset sustained thought type I interferon viral infection viral infections virus
[DOI] 10.1016/j.celrep.2022.111148 PMC 바로가기 [Article Type] Review

ZBP1-dependent inflammatory cell death, PANoptosis, and cytokine storm disrupt IFN therapeutic efficacy during coronavirus infection

ZBP1 의존성 염증 세포 사멸, PANoptosis 및 사이토카인 폭풍은 코로나바이러스 감염 동안 IFN 치료 효능을 방해합니다

Research Articles

Published on 2022-05-192022-09-14
Journal: Science Immunology [Category] Fulltext, SARS, 유전자 메커니즘, 진단,

[키워드] acute respiratory syndrome cell death clinical trial coronavirus coronavirus disease Coronavirus infection COVID-19 Critical Cytokine storm description detrimental effect disrupt domain driving effective Efficacy expected expression Genetic global pandemic identify IFN IFN treatment IFN-β Immune cell IMPROVE Infection Inflammatory cell death inflammatory condition Inflammatory response inhibiting innate immune limit lung Macrophage mechanism MHV mice morbidity and mortality mouse hepatitis virus murine occur pathology patients with COVID-19 responsible SARS-CoV-2 SARS-COV-2 infection shown suppressed the disease therapeutic efficacy Therapeutic strategies therapy Treatment understanding viral infection virus was increased while ZBP1 β-coronavirus β-Coronaviruses
[DOI] 10.1126/sciimmunol.abo6294 PMC 바로가기 [Article Type] Research Articles

2 deoxy-D-glucose augments the mitochondrial respiratory chain in heart

2 deoxy-D-glucose는 심장의 미토콘드리아 호흡 사슬을 증가시킵니다.

Article

Published on 2022-04-272022-09-11
Journal: Scientific Reports [Category] Coronavirus, COVID19(2023년), SARS, 비임상,

[키워드] 2-deoxy-D-glucose accompanied appear approval benefit breath caused cell metabolism clinical trial COVID-19 COVID-19 disease cultured cell cultured cells detrimental effect disease elevated explain fibrosis Glucose Glycolysis heart hypertrophy in vivo increase in India induce metabolism mice mitochondrial Mitochondrial function murine occur opposite oxidative patients with COVID-19 pleiotropic effect Pleiotropic effects Propagation proteome represse Respiration respiratory chain restrict SARS-CoV-2 infected cells SARS-COV-2 infection stimulate Treatment vacuolization viral replication virus while
[DOI] 10.1038/s41598-022-10168-1 PMC 바로가기 [Article Type] Article

Microfluidic Antibody Affinity Profiling Reveals the Role of Memory Reactivation and Cross-Reactivity in the Defense Against SARS-CoV-2

미세유체 항체 친화성 프로파일링은 SARS-CoV-2에 대한 방어에서 기억 재활성화 및 교차 반응성의 역할을 보여줍니다

Article

Published on 2022-04-082022-09-12
Journal: ACS Infectious Diseases [Category] COVID19(2023년), MERS, SARS, 진단,

[키워드] acute SARS-CoV-2 infection ADE adverse effect affinity Against antibody antibody affinity antibody concentration antibody profiling Antibody-dependent enhancement Antigen Concentration convalescent coronavirus Course COVID-19 COVID-19 convalescent patient COVID-19 patient cross-reactive antibodies cross-reactive antibody cross-reactivity Determining detrimental effect effort ELISAs endemic human coronavirus enzyme-linked immunosorbent assay evaluate HCoV-HKU1 HCoV-NL63 humoral immune response Immunity Infection memory memory B-cell memory immunity Microfluidics new SARS-CoV-2 nine parameter Pathogens Profiling Reactivation recent role SARS-CoV-2 SARS-COV-2 infection sequence similarity sera seropositive severity Spike protein the SARS-CoV-2
[DOI] 10.1021/acsinfecdis.1c00486 PMC 바로가기 [Article Type] Article

Genome-wide analyses reveal the detrimental impacts of SARS-CoV-2 viral gene Orf9c on human pluripotent stem cell-derived cardiomyocytes

게놈 전반에 걸친 분석을 통해 SARS-CoV-2 바이러스 유전자 Orf9c가 인간 다능성 줄기 세포 유래 심근세포에 미치는 해로운 영향을 보여줍니다

Article

Published on 2022-03-082022-09-11
Journal: Stem Cell Reports [Category] COVID19(2023년), MERS, SARS, 유전자 메커니즘, 진단, 치료법,

[키워드] Abnormalities abnormality acute respiratory syndrome acute respiratory syndrome coronavirus ameliorated analyses Analysis Apoptosis apoptotic approved ATP ATP synthesis cardiac dysfunction cardiac injury cardiomyocyte caused Cell cellular characterized coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 death defined detrimental detrimental effect detrimental effects disease down-regulated drug Drug administration dysfunction electrical ENCODE expression Factor Factors food functional Genes Genome heart disease heart muscle human pluripotent stem cell Impact Inflammation Injury Ivermectin manifestation Manifestations meclizine meclizine. molecular mechanism molecular mechanisms Orf9c overexpression Pathways Protein Proteins Proteomic analysis reduced respiratory restored SARS-CoV-2 SARS-CoV-2 viral severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 signaling pathways significantly stem cell Therapeutic approach Transcriptomic analyses transcriptomic analysis U.S. Food and Drug Administration up-regulated
[DOI] 10.1016/j.stemcr.2022.01.014 PMC 바로가기 [Article Type] Article

Students’ negative emotions and their rational and irrational behaviors during COVID-19 outbreak

Research Article

Published on 2022-03-072022-10-28
Journal: PLoS ONE [Category] Coronavirus, MERS, SARS,

[키워드] activity addition Adults age analyzed asked BMI body mass index conditions conducted COVID-19 COVID-19 outbreak demographic characteristics detrimental effect effort enrolled event Evidence extreme Factor Gender Health mental health negative emotion negative emotions pandemic question significant difference Spread Stress virus
[DOI] 10.1371/journal.pone.0264985 PMC 바로가기 [Article Type] Research Article

Prevalence and Risk Factors Associated with Postpartum Depression during the COVID-19 Pandemic: A Literature Review and Meta-Analysis

Review

Published on 2022-02-162022-10-29
Journal: International Journal of Environmental Research an [Category] COVID-19, COVID19(2023년), MERS, SARS,

[키워드] Anxiety article Clinical characteristics conducted Consequences coronavirus disease COVID-19 COVID-19 pandemic database defined Depression detrimental detrimental effect eight emotional events Factor Factors global public health Health IMPROVE indicated Intervention lack literature measure Mental Mental disorder Meta-analysis much higher offered outcomes pandemic performed Postpartum Postpartum depression Prevalence prevalence rate professional Psychological Quality random-effect remained Research research finding review risk factor Risk factors searched sensitivity analysis significantly socio-demographic Stress Support systematic review women
[DOI] 10.3390/ijerph19042219 PMC 바로가기 [Article Type] Review

Digital Media Use and Adolescents’ Mental Health During the Covid-19 Pandemic: A Systematic Review and Meta-Analysis

Public Health

Published on 2022-02-012022-10-31
Journal: Frontiers in Public Health [Category] COVID-19, COVID19(2023년), MERS, SARS,

Clinical research on COVID-19: perceptions and barriers to participation in The Gambia

COVID-19에 대한 임상 연구: The Gambia 참여에 대한 인식과 장벽

Article

Published on 2022-02-012022-09-11
Journal: BMJ Global Health [Category] COVID19(2023년), SARS, 임상,

[키워드] acceptability activity administration African Analysis clinical clinical trial clinical trials collected Community conducted COVID-19 COVID-19 testing detrimental effect detrimental effects Developing disease engage enrolled enrolment facilitator facilitators fear foster Government group discussion Health Health Education health education and promotion health system health systems evaluation household contacts identify implementation individual Local local government men MRC n=36 participated patients with COVID-19 Potential treatment Preserving prevention strategies privacy profiles promotion public health recorded Research Safe semistructured interview sick thematic analysis therapy Treatment Trial Trust unit was used West women
[DOI] 10.1136/bmjgh-2021-007533 PMC 바로가기 [Article Type] Article