A novel factor modulating X chromosome dosage compensation in AnophelesArticle Published on 2023-11-062024-08-28 Journal: Current Biology [Category] 말라리아, [키워드] developmental delay female-specific intron retention gene knockout malaria vector male-specific splicing tandem gene duplication.
Tele-care intervention performed by parents involving specific task- environment- participation (STEP protocol) for infants at risk for developmental delay: protocol of randomized controlled clinical trial발달 지연 위험에 처한 영아를위한 특정 작업 환경 참여 (단계 프로토콜)와 관련된 부모가 수행하는 Tele-Care 중재 : 무작위 대조 임상 시험의 프로토콜Study Protocol Published on 2022-01-202022-09-10 Journal: BMC Pediatrics [Category] SARS, 임상, [키워드] activities adopted Affordance age approval assessment assessments Care carried changes clinical control group Controlled clinical trial Controlled trial COVID-19 pandemic development developmental developmental delay distribution Effectiveness Environment ethics committee experimental group Factor family finding healthcare help High-risk infants home home environment Home intervention implementation Infant Infants International Intervention measure motor National pandemic parent parents Participation peer-reviewed performed profile protocol public policies Randomized Registered risk significance level social distancing specific activities statistical analysis supplementary material Support Tele-care therapy two groups university [DOI] 10.1186/s12887-022-03126-3 PMC 바로가기 [Article Type] Study Protocol
Characterization of growth and development of sorghum genotypes with differential susceptibility to Striga hermonthicaArticle Published on 2021-12-042023-08-30 Journal: Journal of experimental botany [Category] E형 간염, [키워드] Striga hermonthica developmental delay gibberellins lateral root metabolism root system architecture sorghum strigolactone [DOI] 10.1093/jxb/erab380 PMC 바로가기
Effects of SARS-CoV-2 Infection During Late Pregnancy on Early Childhood Development: A Prospective Cohort StudyPediatrics Published on 2021-11-232022-10-31 Journal: Frontiers in Pediatrics [Category] COVID-19, [키워드] acute respiratory syndrome affected approved association Breastfeeding childhood children China Chinese Cohort conducted coronavirus coronavirus disease COVID-19 demographic characteristics developmental delay early childhood development Effect enrolled ethics committee Evidence indirect effect Infants Infection infection cohort Linear regression model mediation model medical record Mother-infant separation multivariable Observational cohort study offspring participant Poisson regression model Pregnancy Preterm birth Prospective risk SARS-CoV-2 SARS-COV-2 infection SASRS-COV-2 Science Stage university were used [DOI] 10.3389/fped.2021.750012 PMC 바로가기 [Article Type] Pediatrics
Impact of COVID-19 on Pediatric Clinical ResearchResearch article Published on 2021-11-012022-10-05 Journal: Journal of pediatric nursing [Category] SARS, 임상, [키워드] adjust assessment association calculated caused clinical Clinical research congenital heart disease COVID-19 COVID-19 pandemic determine developmental delay disease enrolled example facilitate healthy control healthy controls Impact implication incidence rate Infant Infants limit Modification modify Novel coronavirus pandemic participant pediatrics performed protocol recruit recruited recruitment reduced Regression Regulation Research Result significantly Spread Stay-at-home order with COVID-19 [DOI] 10.1016/j.pedn.2021.06.005 [Article Type] Research article
Impact of Covid-19 in pregnancy on mother’s psychological status and infant’s neurobehavioral development: a longitudinal cohort study in ChinaResearch Article Published on 2020-11-042022-10-28 Journal: BMC Medicine [Category] COVID-19, SARS, [키워드] addition age association Breastfeeding Child early development China chose cohort study collected data concerning conducted COVID-19 Depression developmental developmental delay disorder disorders domain Evidence Follow-up Healthcare provider Impact induced abortion infection risk interquartile range IQR longitudinal cohort study Maternal Health median medical record Mental disorder mental health mother Neonatal NICU nucleic acid parents participated positive Post-traumatic stress disorder Pregnancy pregnant patient proportion Psychological quarantine questionnaire repeated researcher Result Sex significantly single-arm specimens throat swab transmission of SARS-CoV-2 [DOI] 10.1186/s12916-020-01825-1 PMC 바로가기 [Article Type] Research Article
Mammalian Hbs1L deficiency causes congenital anomalies and developmental delay associated with Pelota depletion and 80S monosome accumulation포유류 Hbs1L 결핍은 Pelota 고갈 및 80S 모노솜 축적과 관련된 선천적 기형 및 발달 지연을 유발합니다Research Article Published on 2019-02-012022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] 4EBP1 accompanied accumulation addition affecting aggregation Anomaly baseline biallelic mutation biallelic mutations binding cause caused Cell cells Characteristics characterized coding region conditions control mechanisms controls Critical deficiency demonstrated Depletion developmental delay downstream Effect Efficiency element expression facial fibroblast fibroblasts functional growth Hbs1L human cell human cells humans hypotonia implicated increase in inhibition involved knockdown lack lead Loss mechanism mice monosome mouse model mRNA mRNA level mTOR mTOR expression murine Mutation ortholog pathway Patient pelo phenotype phenotypic Phosphorylation polysome proteasomal proteasome Protein protein expression Quality control reduced Regulation reported rescued restored resulting ribosomal RNA ribosome ribosomes RNA RT-PCR Sequencing Support the patient These data tissues transcript translation translational upregulation utilization western blot Western blot analyses Western blot analysis yeast [DOI] 10.1371/journal.pgen.1007917 PMC 바로가기 [Article Type] Research Article
Spreading of a Prion Domain from Cell-to-Cell by Vesicular Transport in Caenorhabditis elegansCaenorhabditis elegans의 소포 수송에 의한 세포 간 프리온 도메인의 확산Research Article Published on 2013-03-282022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] aggregate aggregation ALS amyloid Amyotrophic lateral sclerosis animal model appearance asparagine Author autonomous autophagy Caenorhabditis Caenorhabditis elegan Caenorhabditis elegans Cell cellular cellular pathway conformation culture cell cytosolic Degradation developmental delay different disease Diseases domain elegan embryonic Encephalopathy Epigenetic Evidence exhibit expressed expressing expression form Glutamine hallmark hallmarks include infect infectious Lateral Sclerosis lobar lysosomal lysosomal vesicle mechanism misfolded protein misfolded proteins mitochondrial multicellular multicellular organism N-terminus naive cells neurodegenerative neurodegenerative disorders NM organism Parkinson's Disease pathology pathway prion Propagation Protein Proteins real time recent Spread spreading thought tissue tissue culture tissues Toxicity trait transgenic mice transmissible spongiform encephalopathies Transmission Transport underlie Vesicle vesicular widespread yeast [DOI] 10.1371/journal.pgen.1003351 PMC 바로가기 [Article Type] Research Article