Clinical adverse events to dexmedetomidine: a real-world drug safety study based on the FAERS databasePharmacology Original Research Published on 2024-07-022024-09-05 Journal: Frontiers in Pharmacology [Category] update2024, [키워드] Adverse drug reaction adverse events dexmedetomidine FDA adverse event reporting system real-world data analysis [DOI] 10.3389/fphar.2024.1365706 PMC 바로가기 [Article Type] Pharmacology Original Research
Record Setting Temperatures in the Setting of SARS-CoV-2 Suggests Dexmedetomidine Drug-Induced Fever: A Case ReportCase Report Published on 2024-06-132024-09-05 Journal: Journal of investigative medicine high impact case [Category] update2024, [키워드] COVID-19 dexmedetomidine Fever SARS-CoV-2 [DOI] 10.1177/23247096241260959 PMC 바로가기 [Article Type] Case Report
Dexmedetomidine as an Adjuvant in Peripheral Nerve BlockReview Published on 2023-05-172024-09-04 Journal: Drug design, development and therapy [Category] 대상포진, [키워드] adjuvant alpha‑2 agonists analgesic Anesthesia dexmedetomidine Peripheral nerve block [DOI] 10.2147/DDDT.S405294 PMC 바로가기 [Article Type] Review
Study protocol to test the efficacy of self-administration of dexmedetomidine sedative therapy on anxiety, delirium, and ventilator days in critically ill mechanically ventilated patients: an open-label randomized clinical trial중환자 기계 환기 환자의 불안, 섬망 및 인공 호흡기 일에 대한 덱스메데토미딘 진정 요법의 자가 투여 효과를 테스트하기 위한 연구 프로토콜: 공개 라벨 무작위 임상 시험Article Published on 2022-05-162022-09-11 Journal: Trials [Category] 임상, [키워드] addition aggregate alertness alleviate alteration Anxiety approach approaches assigned Care change clinical Clinical practice clinical trial Consistency Course COVID-19 case COVID-19 pandemic Critically ill delirium Depression dexmedetomidine distress Efficacy eligible Eligible participants eligible patient Eligible patients enrolment equipment extubation finding flexible functional Functional status healthcare ICU ICU care ICU patient ICU Patients identify impacted imperative intensive care intensive care unit life management Mechanical mechanical ventilation mechanical ventilatory support mechanically ventilated mechanically ventilated patient mechanically ventilated patients medication Open-label opioid outcome Oxygenation Pain Patient patient symptom Patient symptoms physical Post-traumatic stress disorder Protective protocol Psychological well-being Quality of life randomization Randomized randomized clinical trial Randomly receiving recruitment Secondary objective Secondary objectives Sedation sedative Self-management Side effects significantly study population subset Symptom therapy Trial trial enrolment usual care ventilator ventilator-free day Ventilator-free days ventilatory support [DOI] 10.1186/s13063-022-06391-w PMC 바로가기 [Article Type] Article
Awake pronation with helmet continuous positive airway pressure for COVID-19 acute respiratory distress syndrome patients outside the ICU: A case seriesArticle Published on 2022-02-012023-07-08 Journal: Medicina intensiva [Category] COVID19(2023년), [키워드] Acute respiratory failure ARDS ARF Casco COVID-19 CPAP Dexmedetomidina dexmedetomidine Insuficiencia respiratoria aguda NIV Pandemia pandemic Posición prona Pronación Pronation Prone position SARS-CoV-2 SDRA Síndrome de dificultad respiratoria aguda. [DOI] 10.1016/j.medine.2020.08.009 PMC 바로가기
The Association of an Alpha-2 Adrenergic Receptor Agonist and Mortality in Patients With COVID-19Medicine Published on 2022-01-042022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] 28-day mortality 95% CI Adjusting Adrenergic agonist alpha-2 adrenergic receptor agonist Analysis association Cohort Controlled trial coronavirus disease Coronavirus disease 2019 (COVID-19) COVID-19 demonstrated dexmedetomidine effective evaluated hospital hyperinflammation Immune cell IMPROVE Inflammatory response initiated intubation Invasive mechanical ventilation Mortality multivariable Cox regression observation Oxygenation patients with COVID-19 performed receive receiving receptor reduce reduce mortality reduced reducing mortality Respiratory failure respiratory parameters Retrospective analysis risk reduction Sedation severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) System Treatment university with COVID-19 [DOI] 10.3389/fmed.2021.797647 PMC 바로가기 [Article Type] Medicine
The Efficacy and Safety of Ultrasound-Guided, Bi-Level, Erector Spinae Plane Block With Different Doses of Dexmedetomidine for Patients Undergoing Video-Assisted Thoracic Surgery: A Randomized Controlled Trialarticle Published on 2021-11-252024-09-02 Journal: Frontiers in Medicine [Category] 대상포진, [키워드] dexmedetomidine Erector spinae plane block ropivacaine Ultrasound video-assisted thoracic surgery [DOI] 10.3389/fmed.2021.577885 PMC 바로가기 [Article Type] article
Dexmedetomidine in COVID-19: probing promises with prudence!Comment Published on 2021-08-012023-07-05 Journal: The American journal of emergency medicine [Category] SARS, [키워드] COVID-19 Critical care dexmedetomidine ICU sedation multi-organ dysfunction viral pandemic [DOI] 10.1016/j.ajem.2020.10.034 PMC 바로가기 [Article Type] Comment
Dexmedetomidine: another arrow in the quiver to fight COVID-19 in intensive care unitsComment Published on 2021-01-012023-07-05 Journal: British journal of anaesthesia [Category] SARS, [키워드] COVID-19 dexmedetomidine ICU Inflammation NETosis Sedation [DOI] 10.1016/j.bja.2020.10.010 PMC 바로가기 [Article Type] Comment
Effectiveness of Prone Positioning in Nonintubated Intensive Care Unit Patients With Moderate to Severe Acute Respiratory Distress Syndrome by Coronavirus Disease 2019Observational Study Published on 2021-01-012022-10-05 Journal: Anesthesia and analgesia [Category] 임상, [키워드] acute respiratory distress Administered analyzed approved ARDS baseline Blood Case series change confidence interval coronavirus disease COVID-19 COVID-19 pandemic dexmedetomidine discharged evaluated fractional inspired oxygen ICU ICU patient IMPROVE information intensive care intensive care unit intubation LIGHT maintain mechanical ventilation median mixed-effects model moderate O2 Saturation outcome oxygen Oxygenation Patient patients patients with moderate performed positioning prone prone positioning prospective observational study provided random effect reduce required respiratory Sedation severe ARDS significantly significantly increased Supine position survival syndrome the ethics committee the patient tissue Treatment Two patient university was used WHO with COVID-19 World Health Organization [DOI] 10.1213/ANE.0000000000005239 PMC 바로가기 [Article Type] Observational Study