Susceptibility of SARS-CoV-2 Omicron Variants to Therapeutic Monoclonal Antibodies: Systematic Review and Meta-analysisArticle Published on 2022-08-312022-11-15 Journal: Microbiology Spectrum [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] antibody Antiviral antiviral therapy clinical development Combination combinations conserved COVID-19 Critical Determining disparate effective eight eligible in vitro in vitro activity inactive interquartile range loss of activity measure median monoclonal monoclonal antibody Multidrug resistance Mutation neutralization omicron Omicron variant receptor-binding domains reduced reduction in Region reported review SARS-CoV-2 Spike protein spike receptor-binding domain Standardization susceptibility the median the SARS-CoV-2 therapeutic treating COVID-19 variant variants wild-type [DOI] 10.1128/spectrum.00926-22 PMC 바로가기
RANBP2 and USP9x regulate nuclear import of adenovirus minor coat protein IIIaRANBP2 및 USP9x는 아데노바이러스 마이너 코트 단백질 IIIa의 핵 수입을 조절합니다Article Published on 2022-06-162022-09-11 Journal: PLoS Pathogens [Category] 유전자 메커니즘, [키워드] accumulation acute respiratory illness acute respiratory illnesses Adenovirus Affinity purification Amino acid amino acids Analysis antiviral therapeutics antiviral therapy bind binding blockade C-terminus Cell cell nuclei cells cellular competition conjunctivitis counteract COVID-19 demonstrated deregulated disparate expression Host implication indicated infected cells Infection interact Interaction interactions mass spectrometry maturation mechanism Microscopy nuclear nuclei nucleus outbreak parasites protease Protein Proteins Ranbp2 reduced regulate respiratory pathogen retention subsequent surface plasmon surface plasmon resonance transmission electron microscopy Transport USP9x Vaccine viral genome replication Viral particles Viral protein virion virion assembly virus virus-infected cell virus-infected cells wild type [DOI] 10.1371/journal.ppat.1010588 PMC 바로가기 [Article Type] Article
Evaluation of a Wastewater-Based Epidemiological Approach to Estimate the Prevalence of SARS-CoV-2 Infections and the Detection of Viral Variants in Disparate Oregon Communities at City and Neighborhood ScalesSARS-CoV-2 감염의 유병률을 추정하기 위한 폐수 기반 역학 접근 방식 평가 및 도시 및 인근 지역 규모의 이질적인 오레곤 커뮤니티에서 바이러스 변이체 감지Article Published on 2022-06-012022-09-11 Journal: Environmental health perspectives [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] addition Affect Analysis Asymptomatic Asymptomatic cases authority B.1 city clinically communicable Community Concentration correlated correlation COVID-19 demography detection disease disparate door eight Epidemiology estimate Estimated event examined greater Health authority hotspot identify indicated Infection infections location log nasal swab neighborhood Pearson positive positive correlations Prevalence Previous studies previous study public health quantified Quantitative R 2 Randomized ranged reliability reported SARS-CoV-2 SARS-CoV-2 RNA SARS-CoV-2 variant SARS-CoV-2 variants scalability scale sequenced significantly Surveillance tested Treatment Variation variations wastewater [DOI] 10.1289/EHP10289 PMC 바로가기 [Article Type] Article
Telemedicine in rheumatology: a mixed methods study exploring acceptability, preferences and experiences among patients and cliniciansClinical Trial Published on 2022-05-302022-10-05 Journal: Rheumatology (Oxford, England) [Category] 임상, [키워드] 48 hours Accuracy addition Analysis Autoimmune building Care categories clinician diagnostic digital technology in medicine disparate examined finding greater help inaccuracy Inflammatory arthritis investigated majority methodology Mixed-methods pandemic participant Patient patient selection patient–physician interactions patients preference rare autoimmune rheumatic diseases Registered reported required resolved respond rheumatology risk secondary care Statistical analysis plan survey T-tests Telemedicine training Trial unlikely [DOI] 10.1093/rheumatology/keab796 PMC 바로가기 [Article Type] Clinical Trial
Monitoring COVID-19 on Social Media: Development of an End-to-End Natural Language Processing Pipeline Using a Novel Triage and Diagnosis Approach소셜 미디어에서 COVID-19 모니터링: 새로운 분류 및 진단 접근 방식을 사용한 종단 간 자연어 처리 파이프라인 개발Original Paper Published on 2022-02-282022-09-10 Journal: Journal of Medical Internet Research [Category] COVID19(2023년), MERS, SARS, 치료기술, [키워드] addition Algorithm applied approach assist automatically build category classifiers conditional random fields COVID-19 COVID-19 pandemic COVID-19 symptom COVID-19 symptoms data set develop development diagnose Diagnosis diagnosis of COVID-19 diagnostic disease detection disease detection and surveillance disease symptom disease symptoms disparate F 1 score feature Health Health practitioners identify incidence indicated individual level information language machine learning model macro media medical social media monitoring natural natural language natural language processing novel objective Patient Practitioner predicted Prevalence processing provide public health random reported researcher Result sense severity severity and prevalence social media Support support vector machines Surveillance Symptom Symptoms the disease Triage triage and diagnosis vector yielding [DOI] 10.2196/30397 PMC 바로가기 [Article Type] Original Paper
“You need to dispose of them somewhere safe”: Covid-19, masks, and the pit latrine in Malawi and South AfricaResearch Article Published on 2022-02-222022-10-28 Journal: PLoS ONE [Category] Coronavirus, COVID19(2023년), MERS, SARS, [키워드] addition adopted African cloth mask Community disparate Drawing Face masks finding lack management Mask Masks media mitigate National pandemic prevalent public health respond risk perceptions South South Africa Spread the disease [DOI] 10.1371/journal.pone.0262741 PMC 바로가기 [Article Type] Research Article
Future-proofing and maximizing the utility of metadata: The PHA4GE SARS-CoV-2 contextual data specification package메타데이터의 미래 대비 및 활용 극대화: PHA4GE SARS-CoV-2 상황별 데이터 사양 패키지Technical Note Published on 2022-02-162022-09-10 Journal: GigaScience [Category] COVID19(2023년), MERS, SARS, 유전자 메커니즘, 진단, 치료기술, [키워드] Accessibility adoption aggregation Alliance array best bioinformatics biorepositories Community Consensus Consistency COVID-19 Critical data standards database dataset datasets disparate document facilitate Genomics greater IMPROVE information integration interoperability Metadata microbial package pandemic promote protocol protocols Public public health reproducibility resources Result reuse SARS-CoV-2 sequence specification submission Support supported utility [DOI] 10.1093/gigascience/giac003 PMC 바로가기 [Article Type] Technical Note
Structural racism and COVID-19 response: higher risk of exposure drives disparate COVID-19 deaths among Black and Hispanic/Latinx residents of Illinois, USAResearch Published on 2022-02-152022-10-28 Journal: BMC Public Health [Category] COVID-19, COVID19(2023년), Fulltext, MERS, SARS, [키워드] addition age all age groups black calculated case fatality ratio Community COVID COVID-19 COVID-19 case COVID-19 cases COVID-19 pandemic death death rate deaths diagnostic testing diagnostic tests disease disparate disparity drastic driver driving employment Epidemic Factor fatality groups Health healthcare help higher risk identify Illinois incidence individual Intervention lack less Local Mortality outcome Population populations Public Racial disparities reached reduce reducing Relative risk Result resulting risk risk of COVID-19 SARS-CoV-2 significantly increased stratified supplementary material System the epidemic The United States USA white [DOI] 10.1186/s12889-022-12698-9 PMC 바로가기 [Article Type] Research
There are no equal opportunity infectors: Epidemiological modelers must rethink our approach to inequality in infection riskPerspective Published on 2022-02-092022-10-28 Journal: PLoS Computational Biology [Category] COVID-19, COVID19(2023년), Fulltext, MERS, SARS, [키워드] accounted acute infection aggregate approach cause characterized consequence contrary COVID-19 pandemic develop disease disparate driver evaluate Evidence example exclusion Factor Factors global pandemic Health helping HIV hospital Infection infection risk infections Infectious disease local response mathematical model mechanisms National Nonpharmaceutical interventions outbreak outcome question Racial raise Research SARS-CoV-2 Transmission [DOI] 10.1371/journal.pcbi.1009795 PMC 바로가기 [Article Type] Perspective
Social Determinants of Disease: HIV and COVID-19 ExperiencesThe Global Epidemic (S Vermund, Section Editor) Published on 2022-02-022022-10-31 Journal: Current HIV/AIDS reports [Category] Coronavirus, COVID19(2023년), MERS, SARS, [키워드] analyzed article articles cause Community contributing to COVID-19 COVID-19 transmission determinant disease disparate equity experience Factor finding Health Health disparities health equity Health inequity healthcare highlight HIV HIV/AIDS identify infections Intersection Intervention meet Pandemics Prevalence public health Racial Racial/ethnic minorities recent review robust social determinants of health Social service stability Structural racism Support with COVID-19 [DOI] 10.1007/s11904-021-00595-6 PMC 바로가기 [Article Type] The Global Epidemic (S Vermund, Section Editor)