Prevalence of Positive Rapid Antigen Tests After 7-Day Isolation Following SARS-CoV-2 Infection in College Athletes During Omicron Variant PredominanceArticle Published on 2022-10-032022-11-16 Journal: JAMA Network Open [Category] COVID19(2023년), SARS, 변종, [키워드] 95% CI age Analysis analyzed Antigen Asymptomatic athlete Case series case sery center college contagious Control determine disease division heterogeneous population individual Infection Isolation omicron outcome positive positive result prevention proportion Rapid rapid antigen test remained representing SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 variant significantly more Spread subsequent symptom status symptomatic symptomatic infection Test tested variant variants [DOI] 10.1001/jamanetworkopen.2022.37149 PMC 바로가기
Early reduction of estimated Glomerular Filtration Rate (eGFR) predicts poor outcome in acutely ill hospitalized COVID-19 patients firstly admitted to medical regular wards (eGFR-COV19 study)Research article Published on 2022-09-012022-10-05 Journal: Biomedicine & pharmacotherapy = Biomédecine & phar [Category] COVID19(2023년), SARS, 바이오마커, [키워드] Acute kidney injury Admission age Analysis analyzed ARDS association AUC Autopsy baseline value calculated Chronic kidney disease correlated COVID-19 creatinine diagnosed died discharge division Efficacy GFR glomerular filtration rate hospital Hospital admission hospital discharge hospitalized COVID-19 patient hospitalized patient ICU identify IL-6 IMV In-hospital death in-hospital mortality Infection intensive care internal Invasive mechanical ventilation KDIGO AKI kidney Kidney injury mechanical ventilation Medicine NIV non-invasive ventilation outcome Patient patients patients’ medical record predict Predictive Primary outcome Prognosis Rate reduction renal dysfunction renal function representing Result SARS-CoV-2 score Secondary outcomes Serum level significantly significantly lower statistical analysis symptomatic Symptoms tissue were assessed with COVID-19 [DOI] 10.1016/j.biopha.2022.113454 [Article Type] Research article
Single-cell transcriptomic profiling of lung endothelial cells identifies dynamic inflammatory and regenerative subpopulations폐 내피 세포의 단일 세포 전사체 프로파일링은 동적 염증 및 재생 하위 집단을 식별합니다Article Published on 2022-06-082022-09-11 Journal: JCI Insight [Category] COVID19(2023년), SARS, 신종인플루엔자, 유전자 메커니즘, [키워드] Activation Bacterial infections baseline Cell Clustering defined demonstrated division endothelial endothelial cells Endothelium expression Gene Expression H1N1 H1N1 influenza H1N1 influenza virus heterogeneity identify immune response gene immune response genes increased expression infected with SARS-CoV-2 Infectious disease Inflammatory inflammatory lung injury inflammatory signaling Influenza Injury labor limit LPS lung lung endothelial Lung injury MHC gene MHC genes murine organ overexpression Pathway analysis performed phenotypic prevented proliferative promote Pulmonology regeneration regenerative respond Seurat single-cell single-cell RNA-seq Sox17 subpopulation targeted therapy transcriptomic Vascular vascular bed vascular endothelial cell vascular endothelial cells virus [DOI] 10.1172/jci.insight.158079 PMC 바로가기 [Article Type] Article
Immunogenicity and safety of homologous and heterologous ChAdOx1-S and mRNA-1273 vaccinations in healthy adults in Taiwan대만의 건강한 성인에서 동종 및 이종 ChAdOx1-S 및 mRNA-1273 백신 접종의 면역원성과 안전성Article Published on 2022-06-012022-09-12 Journal: Journal of Clinical Virology [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] Abbott Diagnostics age antibody production Antibody Response Antibody titer booster doses ChAdOx1-S collected COVID-19 COVID-19 vaccine COVID-19 vaccines cPass™ detection division Elecsys® Anti-SARS-CoV-2 S Genscript Germany healthy Heterologous heterologous prime-boost homologous Homologous and heterologous prime-boost regimens homologous or heterologous humoral immune response IgG immunogenicity induce Ireland Moderna mRNA-1273 Neutralizing New Participants priming regimen robust Roche Diagnostics Safe Safety safety profile SARS-CoV-2 SARS-CoV-2 IgG serum sample shown Sligo Taiwan USA vaccination Vaccine were given were measured [DOI] 10.1016/j.jcv.2022.105156 PMC 바로가기 [Article Type] Article
IgM anti-ACE2 autoantibodies in severe COVID-19 activate complement and perturb vascular endothelial functionClinical Medicine Published on 2022-05-092022-10-04 Journal: JCI Insight [Category] COVID19(2023년), MERS, SARS, 유전자 메커니즘, 진단, 치료기술, [키워드] 95% CI ACE2 activate activated Activation acute respiratory distress analyzed angiotensin-converting enzyme 2 autoantibody Autoimmunity Award Biomarker Blood career changes in class-switching clinical feature Clinical outcome complement contribute coronavirus SARS-CoV-2 COVID-19 demonstrated development disease division Donald Effect ELISA Endothelial cell endothelial function expressed foundation functional Gate heart Host immune response identify IgG IgM Implications independent initiated Inpatients Intramural Jerome Melinda Gate NIH Non-COVID-19 pathology Patient patients with moderate receptor recognizing Result rheumatology SARS-COV-2 infection Science severe COVID-19 severe disease syndrome T cell the SARS-CoV-2 therapeutic undergo Vascular Vascular endothelium ventilated patient vessel [DOI] 10.1172/jci.insight.158362 PMC 바로가기 [Article Type] Clinical Medicine
Gatekeeper training for vendors to reduce pesticide self-poisoning in rural South Asia: a study protocol for a stepped-wedge cluster randomised controlled trial남아시아 농촌 지역에서 살충제 중독을 줄이기 위한 공급업체를 위한 게이트키퍼 교육: 계단식 쐐기형 클러스터 무작위 통제 시험을 위한 연구 프로토콜Article Published on 2022-04-042022-09-11 Journal: BMJ Open [Category] Coronavirus, 임상, [키워드] 24 hours alcohol approved Asia Attempted suicide Cluster Committee conducted COVID-19 division divisions Edinburgh Effectiveness Ethics ethics committee evaluate faculty Faculty of Medicine form high risk hospital identify individual Intervention introduced kill Other outcome outcome measure outcome measures peer-reviewed pesticide pesticides poisoning Prevent Primary outcome public health random randomised controlled trial Randomised trial reduce registration number Research Ethics restriction Result review secondary Secondary outcomes self-harm South Study protocol Suicide suicide & Surveillance toxicology university [DOI] 10.1136/bmjopen-2021-054061 PMC 바로가기 [Article Type] Article
Unsupervised explainable AI for molecular evolutionary study of forty thousand SARS-CoV-2 genomesResearch Published on 2022-03-102022-10-28 Journal: BMC Microbiology [Category] COVID-19, MERS, SARS, [키워드] applied big data changes clade clades Cluster Clustering complement concerning COVID-19 division feature FIVE Genome genome sequence genomic region genomic sequence hidden information knowledge modifications molecular oligonucleotide PCR primer Phylogenetic provided public health responsible Result reveal RNA SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 genomes sequence supplementary material Therapeutic oligonucleotide viral adaptation virus while zoonotic virus [DOI] 10.1186/s12866-022-02484-3 PMC 바로가기 [Article Type] Research
Comparison of SARS-CoV-2 Test Positivity in NCAA Division I Student Athletes vs Nonathletes at 12 InstitutionsResearch Published on 2022-02-092022-10-29 Journal: JAMA Network Open [Category] COVID-19, COVID19(2023년), MERS, SARS, [키워드] 95% CI Analysis analyzed athlete country COVID-19 COVID-19 pandemic cross-sectional cross-sectional analysis designation division evaluate exposure Final finding Hypothesis identify Importance increased risk increases in Infection institution measure median objective outcome participant performed Point Population Positive test power press protocol Release released Relevance reported Result risk risk of COVID-19 Safe SARS-CoV-2 SARS-CoV-2 test SARS-CoV-2 transmission School setting Stanford Stanford University state statistically significant difference student Test Travel university was increased was performed [DOI] 10.1001/jamanetworkopen.2021.47805 PMC 바로가기 [Article Type] Research
The impact of the COVID-19 pandemic and associated suppression measures on the burden of tuberculosis in IndiaResearch Published on 2022-01-272022-10-28 Journal: BMC Infectious Diseases [Category] Coronavirus, SARS, [키워드] absence accelerate association available data average changed characterized correlated COVID-19 COVID-19 pandemic death determine Diagnosis diagnostic division expected Factor greater help highest Hospital admission identify impacted IMPROVE India information Intervention Linear regression lockdown logit measure Mobility pandemic performed Poisson model reported Research Result state supplementary material territory Tuberculosis [DOI] 10.1186/s12879-022-07078-y PMC 바로가기 [Article Type] Research
Assessment of Regional Variability in COVID-19 Outcomes Among Patients With Cancer in the United StatesResearch Published on 2022-01-042022-10-29 Journal: JAMA Network Open [Category] COVID-19, [키워드] 30-Day mortality 30-day mortality rate 95% CI adjusted adjusted odds ratio Admission age all-cause mortality assessment association Attention black Cancer Cancer center Care Characteristics cohort study collected Community continuum COVID-19 COVID-19 diagnosis COVID-19 pandemic death Diagnosis division divisions exposure female finding help heterogeneity higher risk Hispanic Importance IMPROVE individuals intensive care invasive laboratory-confirmed SARS-CoV-2 infection less measure mechanical ventilation median mixed-effects model mortality rate neoplasm no significant difference objective oncology outcome outcomes participant Patient patient population Patients with cancer Point Primary outcome quantified ranged Regional Relevance reported resource Result retrospective cohort study risk factor Secondary outcomes setting severe complication significant difference significantly South spatiotemporal statistically significant difference the United State The United States Treatment Variation vulnerable patients West [DOI] 10.1001/jamanetworkopen.2021.42046 PMC 바로가기 [Article Type] Research