The Bright Side of Curcumin: A Narrative Review of Its Therapeutic Potential in Cancer ManagementReview Published on 2024-07-182024-09-05 Journal: Cancers [Category] update2024, [키워드] Anticancer agent antitumor drugs Cancer cell metabolism Chemotherapy Curcuminoid drug delivery drug targeting nanoparticle oxidative phosphorylation oxidative stress photochemotherapies photodynamic therapy Tumor turmeric [DOI] 10.3390/cancers16142580 PMC 바로가기 [Article Type] Review
Protein structure-based in-silico approaches to drug discovery: Guide to COVID-19 therapeuticsReview Published on 2023-06-012023-07-10 Journal: Molecular aspects of medicine [Category] COVID19(2023년), [키워드] artificial intelligence COVID-19 drug targeting mathematical modeling Rational improvement SARS-CoV-2 Target-based drug discovery. [DOI] 10.1016/j.mam.2022.101151 PMC 바로가기 [Article Type] Review
Evolution of drug delivery systems: From 1950 to 2020 and beyondArticle Published on 2022-02-012023-07-07 Journal: Journal of controlled release : official journal o [Category] COVID19(2023년), [키워드] Biological barriers drug delivery drug targeting Evolution history Long-term treatment. [DOI] 10.1016/j.jconrel.2021.12.030 PMC 바로가기
Multifunctional Gold Nanoparticles for Improved Diagnostic and Therapeutic Applications: A ReviewNano Review Published on 2021-12-052022-10-30 Journal: Nanoscale Research Letters [Category] COVID-19, [키워드] anticancer approval approved AuNP benefit Bio-functionalization can be used clinical trial clinical trials clinically Combination disease Disease diagnosis drug drug delivery drug targeting Efficacy FDA food gold Gold nanoparticles Health IMPROVE Improved Infection Metal-based therapy Multimodal systems nanoparticle offer reduced review shown the United State therapeutic therapy threat Treatment unique variety [DOI] 10.1186/s11671-021-03632-w PMC 바로가기 [Article Type] Nano Review
Positive selection as a key player for SARS-CoV-2 pathogenicity: Insights into ORF1ab, S and E genesSARS-CoV-2 병원성의 핵심 플레이어로 양성 선택: ORF1ab, S 및 E 유전자에 대한 통찰력Article Published on 2021-09-012022-09-11 Journal: Virus research [Category] SARS, 치료기술, 치료제, [키워드] adaptive Analysis approaches C-terminal cause codon Codons composed COVID-19 disease disease domain drug drug targeting E gene E protein Each encoded proteins Evidence evidence of Evolution functional Genes Host Host immune response Human hydrophilic in viral inhibiting insight involved likelihood maximum Maximum likelihood N-terminal domain non-structural protein non-structural proteins nonstructural protein nsp1 Nsp3 ORF1 ORF1a ORF1ab ORF1b pandemic pathogenicity performed Positive selection Protein protein domains protein-coding gene residues SARS-CoV-2 SARS-CoV-2 epidemic SARS-CoV-2 genome SARS-CoV-2 genomes Ser stability structural protein structural proteins Substitution substitutions survival target targets the S protein the SARS-CoV-2 Transcription translation transmembrane transmembrane domain Transmissibility Vaccine viral replication virulent virus vital role vital roles Wuhan Wuhan, China β-coronavirus [DOI] 10.1016/j.virusres.2021.198472 PMC 바로가기 [Article Type] Article
Repurpose but also (nano)-reformulate! The potential role of nanomedicine in the battle against SARS-CoV2Review Published on 2021-07-202023-07-01 Journal: Journal of controlled release : official journal o [Category] SARS, [키워드] COVID-19 drug delivery Drug repurposing drug targeting inhalation therapy nanomedicine [DOI] 10.1016/j.jconrel.2021.07.028 PMC 바로가기 [Article Type] Review
Integrated network analysis reveals new genes suggesting COVID-19 chronic effects and treatment통합 네트워크 분석, COVID-19 만성 영향 및 치료를 시사하는 새로운 유전자 발견Case Study Published on 2021-03-112022-09-10 Journal: Briefings in Bioinformatics [Category] SARS, 신약개발, 유전자 메커니즘, 치료제, [키워드] Analysis applied coronavirus COVID-19 COVID-19 disease COVID-19 pathogenesis Data integration develop drug repositioning drug targeting drugs targeting Effect Effects fibrosis generate health emergency help heterogeneity host response identify in vitro in vivo Infection involved lack limitation multi-layer network analysis network analysis Protein reveal SARS-CoV-2 Space systemic effect the SARS-CoV-2 therapeutic strategy Treatment unified knowledge space Vaccine vascular remodelling virus virus–host interaction [DOI] 10.1093/bib/bbaa417 PMC 바로가기 [Article Type] Case Study
Autophagy and SARS-CoV-2 infection: A possible smart targeting of the autophagy pathwayEditorial Published on 2020-06-222022-10-28 Journal: Virulence [Category] COVID-19, MERS, SARS, [키워드] acting activate acute respiratory syndrome administration adverse effect Apoptosis apoptotic death apoptotic pathway approved autophagy autophagy flux Betacoronavirus Cell clinical trials confirmed case coronavirus cross-talk death disrupt drug drug targeting drugs Effect FDA-approved drug infected cell Infection inhibit Macroautophagy molecular mechanism nanomedicine nanoparticle Nanoparticles outbreak overcome pathway powerful tool SARS-CoV-2 SARS-COV-2 infection severe adverse effect Spread suggested Treatment virus virus infection virus replication viruses WHO [DOI] 10.1080/21505594.2020.1780088 PMC 바로가기 [Article Type] Editorial
Active migration and passive transport of malaria parasitesarticle Published on 2015-08-312024-09-01 Journal: Trends in Parasitology [Category] 말라리아, [키워드] active migration drug targeting parasite dissemination passive transport Vaccine design [Article Type] article