Insights from the Infection Cycle of VSV-ΔG-Spike VirusArticle Published on 2022-12-192023-07-11 Journal: Viruses [Category] COVID19(2023년), [키워드] electron tomography RNA virus Spike protein transmission electron microscopy vesicular stomatitis virus viral factories. [DOI] 10.3390/v14122828 PMC 바로가기
Severe Acute Respiratory Syndrome Coronavirus 2 Viremia Is Associated With Coronavirus Disease 2019 Severity and Predicts Clinical Outcomes중증 급성 호흡기 증후군 코로나바이러스 2 바이러스혈증은 코로나바이러스 질병 2019 심각도와 연관되어 있으며 임상 결과를 예측합니다Observational Study Published on 2022-05-032022-09-11 Journal: Clinical Infectious Diseases: An Official Publicat [Category] COVID19(2023년), MERS, SARS, 바이오마커, 임상, 진단, 치료기술, [키워드] 19 outcome 2 RNAemia 2 viremia acute respiratory syndrome acute respiratory syndrome coronavirus Admission Antibody titers bloodstream Care clinical clinical outcomes Cohort coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 CoV COVID COVID-19 COVID-19 patient COVID-19 severity cross-sectional discharge disease severity electron tomography hazard ratio Health Organization Hospitalized Host immune response host immune responses ICU ICU Patients immune responses immunostaining indicate Inflammatory biomarker Inpatients Level Mortality Neutralizing antibody titer neutralizing antibody titers non-ICU outcome outcomes Outpatient outpatients Patient pellet plasma plasma sample plasma samples quantified reflect respiratory SARS SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 significantly significantly higher Viral Viral RNA Viremia virion virions virus particle virus particles Visualization vRNA WHO World Health Organization [DOI] 10.1093/cid/ciab686 PMC 바로가기 [Article Type] Observational Study
Morphometry of SARS-CoV and SARS-CoV-2 particles in ultrathin plastic sections of infected Vero cell culturesArticle Published on 2021-02-102022-10-29 Journal: Scientific Reports [Category] COVID-19, [키워드] appear both virus Cell Cell culture complement COVID-19 disease Culture electron tomography Epidemiology Frankfurt globe infancy information isolates median Microscopy morphology particle size distribution SARS virus SARS-CoV SARS-CoV-2 SARS-CoV-2 particle spike spikes Spread the disease the SARS-CoV-2 Treatment Ultrastructural analysis Vero Cell virus was related while [DOI] 10.1038/s41598-021-82852-7 PMC 바로가기 [Article Type] Article
Integrative Imaging Reveals SARS-CoV-2-Induced Reshaping of Subcellular Morphologies통합 이미징은 SARS-CoV-2에 의해 유도된 세포 내 형태의 재구성을 보여줍니다Article Published on 2020-12-092022-09-12 Journal: Cell Host & Microbe [Category] MERS, SARS, 진단, [키워드] alteration Analysis biogenesis Cell cell death Cluster coronavirus cytokine response Cytopathic effect cytoskeleton dataset determine electron tomography elements Endoplasmic reticulum epithelial cells FIB-SEM Golgi Golgi apparatus human lung imaging Infection intermediate filaments live cell imaging membrane membrane remodeling Microscopy mitochondrial Morphological organelle peroxisome peroxisomes recruitment Repository reveal SARS-CoV-2 SARS-CoV-2 replication SARS-CoV-2-infected cell subcellular suppresse thought Vesicle viral replication viral replication organelles. [DOI] 10.1016/j.chom.2020.11.003 PMC 바로가기 [Article Type] Article
Infectious Bronchitis Virus Nonstructural Protein 4 Alone Induces Membrane PairingArticle Published on 2018-09-062022-10-28 Journal: Viruses [Category] Coronavirus, [키워드] bronchitis Cell cellular membrane Combination coronavirus Coronaviruses Effect electron tomography Endoplasmic reticulum expressing expression Factor highlight Host IBV indicate induce Infectious Bronchitis Virus investigated mechanism membrane membrane rearrangements membrane vesicle Microscopy non-structural protein Nsp3 nsp4 Nsps organelle paired membranes Pairing pathogenic Proteins Replication replicative required responsible RNA viruses shown spherules strain structures transmembrane transmembrane protein vesicles Viral protein viral RNA synthesis virus were expressed zippered ER [DOI] 10.3390/v10090477 PMC 바로가기 [Article Type] Article
Expression and Cleavage of Middle East Respiratory Syndrome Coronavirus nsp3-4 Polyprotein Induce the Formation of Double-Membrane Vesicles That Mimic Those Associated with Coronaviral RNA ReplicationResearch Article Published on 2017-11-212022-10-29 Journal: mBio [Category] Coronavirus, [키워드] acute respiratory syndrome Affect biogenesis cleavage coexpressed convoluted membranes coronavirus Coronaviruses cytoplasmic electron tomography element Endoplasmic reticulum eukaryote Evidence expressed Formation highlight Human in viral induce lethal infection maturation membrane structure membranes MERS-CoV Middle East MIMIC Mutagenesis nidovirus nidoviruses nonstructural protein nonstructural proteins Nsp3 nsp4 organelle pathogen Pathogens polyprotein positive precursor proliferation Protein proteolytic Replication replication complex replication organelle biogenesis replication structures required Research respiratory respiratory syndrome coronavirus RNA RNA synthesis RNA virus SARS-CoV similarity subunit suggested thought transmembrane transmembrane domains transmembrane protein Vesicle viral double-stranded RNA viral factory Viral protein [DOI] 10.1128/mBio.01658-17 PMC 바로가기 [Article Type] Research Article
Parasitophorous vacuole poration precedes its rupture and rapid host erythrocyte cytoskeleton collapse in Plasmodium falciparum egressArticle Published on 2017-03-282024-08-27 Journal: Microbial Cell Factories [Category] 말라리아, [키워드] egress electron energy loss spectroscopy electron tomography malaria soft X-ray microscopy.
Electron tomography characterization of hemoglobin uptake in Plasmodium chabaudi reveals a stage-dependent mechanism for food vacuole morphogenesisarticle Published on 2016-05-312024-09-01 Journal: Journal of Structural Biology [Category] 말라리아, [키워드] electron tomography freeze substitution Hemozoin high-pressure freezing Plasmodium rodent malaria Three-dimensional reconstruction [Article Type] article
Biogenesis and architecture of arterivirus replication organellesArticle Published on 2016-04-092022-11-01 Journal: Virus research [Category] Coronavirus, [키워드] analysed arteritis arterivirus biogenesis cell line comparable coronavirus Coronaviruses Correlative light-electron microscopy described electron tomography endoplasmic reticulum membranes equine eukaryotic Express expressed expression groups hepatitis C virus homogenous host cell membrane induce infected cells Infection knowledge membrane curvature Membrane remodelling modulating Nidovirale Nidovirales nidoviruses NSP2 Nsp3 organelle picornavirus polyprotein Protein question Regulatory Replication replication complex replication structures RNA RNA synthesis Structure subset Support thought Three-dimensional electron microscopy Topology transmembrane protein Vesicle viral infection viral RNA synthesis virus viruses [DOI] 10.1016/j.virusres.2016.04.001 PMC 바로가기 [Article Type] Article
Membranous Replication Factories Induced by Plus-Strand RNA VirusesReview Published on 2014-07-222023-08-29 Journal: Viruses [Category] E형 간염, [키워드] Coronaviruses double-membrane vesicles electron microscopy electron tomography flaviviruses hepatitis C virus membrane rearrangements membranous replication factories picornaviruses ultrastructure [DOI] 10.3390/v6072826 PMC 바로가기 [Article Type] Review