Caveolin-1 mediates blood-brain barrier permeability, neuroinflammation, and cognitive impairment in SARS-CoV-2 infectionArticle Published on 2024-06-092024-09-05 Journal: Journal of neuroimmunology [Category] update2024, [키워드] blood-brain barrier Brain caveolin-1 CD3 claudin-5 endothelial Neuroinflammation Novel object recognition SARS-CoV-2 T cell [DOI] 10.1016/j.jneuroim.2024.578309 PMC 바로가기 [Article Type] Article
Adrenal Cysts: To Operate or Not to Operate?Review Published on 2024-02-012024-09-05 Journal: Journal of Clinical Medicine [Category] update2024, [키워드] adrenal cyst adrenal gland surgery COVID-19 endothelial SARS-CoV-2 [DOI] 10.3390/jcm13030846 PMC 바로가기 [Article Type] Review
The choline-binding proteins PspA, PspC, and LytA of Streptococcus pneumoniae and their interaction with human endothelial and red blood cells스트렙토코쿠스 뉴모니아의 콜린 결합 단백질 PspA, PspC 및 LytA와 이들의 인간 내피세포 및 적혈구와의 상호작용Article Published on 2023-09-082024-07-28 Journal: Infection and Immunity [Category] 폐렴구균 감염증, [키워드] Biofilms cell wall endothelial Hemolysis hemolytic uremic syndrome immune evasion [DOI] 10.1128/iai.00154-23 PMC 바로가기
Chip-Based Assay of Adhesion of Plasmodium falciparum-Infected Erythrocytes to Cells Under Flowarticle Published on 2022-12-312024-09-01 Journal: Methods in molecular biology (Clifton, N.J.) [Category] 말라리아, [키워드] Adhesion assay binding endothelial Flow Fluidic hCMEC/D3 malaria Microvascular P. falciparum receptors [Article Type] article
Subtle vascular and astrocytic changes in the brain of coronavirus disease 2019 (COVID-19) patientsArticle Published on 2022-12-012022-11-15 Journal: European journal of neurology [Category] COVID19(2023년), SARS, 진단, [키워드] Activation acute respiratory syndrome analysed Analysis AQP4 aquaporin 4 Astrocyte astrocytes Blood Brain brain blood vessels calculated CD31 Central nervous system change changes changes in co-expression collagen control patient controls coronavirus coronavirus disease COVID-19 COVID-19 cases COVID-19 patients decrease described endothelial fluorescent Fractal dimension GFAp immunohistochemistry Infection inflammatory signalling light microscopy lymphocyte membrane membranes microglial morphological change morphology Patient patients perivascular Protein reduced reduction SARS-CoV-2 SARS-COV-2 infection significantly increased Vascular vascular basement membranes. vessel [DOI] 10.1111/ene.15545 PMC 바로가기
Coronavirus disease 2019 subphenotypes and differential treatment response to convalescent plasma in critically ill adults: secondary analyses of a randomized clinical trialArticle Published on 2022-11-012022-11-15 Journal: Intensive care medicine [Category] Fulltext, MERS, 바이오마커, [키워드] ABO-compatible convalescent plasma Adaptive platform trial Adults Analysis assigned Biomarker Biomarkers chemokines community-acquired pneumonia convalescent plasma Convalescent plasma therapy coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient Critically ill critically ill patients Cytokines difference effector immune responses elevated endothelial explain heterogeneous homogeneous Hypothesis immunologically immunotherapies Inflammation IQR median multifactorial organ support outcome outcomes patients Population precision medicine Prevalence Randomized randomized clinical trial RCT RCTs REMAP-CAP reported secondary analysis Subphenotypes. tested therapy treatment effect Treatment response usual care with COVID-19 [DOI] 10.1007/s00134-022-06869-w PMC 바로가기
SARS-CoV-2 infection and replication kinetics in different human cell types: The role of autophagy, cellular metabolism and ACE2 expressionArticle Published on 2022-11-012022-11-16 Journal: Life sciences [Category] SARS, 유전자 메커니즘, [키워드] A549 ACE2 ACE2 expression angiotensin ATP synthase autophagy BEAS-2B Brain Caco-2 can be used Cell cell line cell lines cellular cellular metabolism COVID-19 COX endothelial energy metabolism evaluated expression level HEK-293 human cell human cell line in vitro intestine intrinsically investigated kidney liver mechanism metabolism Mitochondria mitochondrial metabolism modified cell line molecular mechanism mRNA expression NDUFS2 overexpressed overexpressing overexpression Protein Replication replication kinetics respiratory tract RT-qPCR SARS-COV-2 infection SARS-CoV-2 replication SH-SY5Y susceptibility susceptible cell TMPRSS2 TMPRSS2 expression uninfected cell various tissue viral infection Viral load viral replication were assessed western blot [DOI] 10.1016/j.lfs.2022.120930 PMC 바로가기
Delayed anti-VEGF injections during the COVID-19 pandemic and changes in visual acuity in patients with three common retinal diseases: A systematic review and meta-analysisArticle Published on 2022-11-012022-11-15 Journal: Survey of Ophthalmology [Category] 진단, [키워드] 95% CI 95% confidence interval Age-related macular degeneration analyses anti-vascular Anti-VEGF changes in COVID-19 COVID-19 pandemic database Delayed Diabetic Diabetic macular edema edema endothelial growth factor injection less lockdown logarithm measure Meta-analysis Neovascular age-related macular degeneration pandemic Patient patients performed random-effects model reported Result Retinal Retinal disease retinal vein retinal vein occlusion searched systematic review systematic review and meta-analysis the mean Treatment visual acuity Web of Science worsened [DOI] 10.1016/j.survophthal.2022.08.002 PMC 바로가기
Microvascular and proteomic signatures overlap in COVID-19 and bacterial sepsis: the MICROCODE studyArticle Published on 2022-11-012022-11-15 Journal: Angiogenesis [Category] 바이오마커, 유전자 메커니즘, [키워드] 28-day mortality adult COVID-19 patients Analysis Bacterial Bacterial sepsis Biomarker clinical outcomes Clinical severity Cluster Cohort conditions coronavirus disease Correlation analysis COVID-19 COVID-19 patient dimension disease disease entity dysfunction endothelial Endothelial dysfunction explained Health healthy control high mortality Hospitalized hospitals host response impairment independent intubation marker Microcirculation Microscopy Microvascular dysfunction microvascular injury outcome analysis outcomes overlap patients plasma plasma protein predict predictor Protein proteome proteomic Proteomic signature proteomics quantified Sepsis Variation was performed was used were measured were used [DOI] 10.1007/s10456-022-09843-8 PMC 바로가기
Integrative analyses of genes about venous thromboembolism: An umbrella review of systematic reviews and meta-analysesArticle Published on 2022-10-282022-11-16 Journal: Medicine [Category] meta-analysis, 변종, [키워드] activating Analysis appraisal checklist conducted COVID-19 vaccination criteria Critical cumulative database Effect effect size eligible endothelial environmental risk factor Epidemiology estimates etiology Evidence Genetic genetic risk factor Genetic variant Genetic variations had more heterogeneity Human identify Intervention meta-analyses Meta-analysis MTHFR network p values performed polymorphism protease Protein prothrombin provided receptor respond review risk Risk factors Sample size selected surgical systematic review variable variant Venice venous Venous Thromboembolism VTE was performed were used [DOI] 10.1097/MD.0000000000031162 PMC 바로가기