Structural and genomic analysis of single nucleotide polymorphisms in human host factor endothelial protein C receptor (EPCR) reveals complex interplay with malaria parasitesarticle Published on 2023-06-302024-09-01 Journal: Infection, Genetics and Evolution [Category] 말라리아, [키워드] endothelial protein C receptor EPCR PfEMP1 CIDRα1, severe malaria Structural mapping [Article Type] article
Microvascular Environment Influences Brain Microvascular Heterogeneity: Relative Roles of Astrocytes and Oligodendrocytes for the EPCR Expression in the Brain EndotheliumArticle Published on 2023-04-072024-08-28 Journal: International Journal of Molecular Sciences [Category] 말라리아, [키워드] astrocytes Blood–brain barrier cerebral blood vessels cerebral malaria endothelial protein C receptor Grey matter heterogeneity oligodendrocytes White matter
Plasmodium falciparum Parasite Lines Expressing DC8 and Group A PfEMP1 Bind to Brain, Intestinal, and Kidney Endothelial Cells플라스모디움 팔시파룸 기생충 계통이 DC8 및 그룹 A PfEMP1을 발현하여 뇌, 장 및 신장 내피 세포에 결합합니다.Original Research Published on 2022-01-282024-08-08 Journal: Frontiers in Cellular and Infection Microbiology [Category] 말라리아, [키워드] cytoadhesion endothelial protein C receptor intestinal endothelial cell kidney endothelial cell malaria Plasmodium falciparum [DOI] 10.3389/fcimb.2022.813011 PMC 바로가기 [Article Type] Original Research
Pathogenic lipid-binding antiphospholipid antibodies are associated with severity of COVID-19병원성 지질 결합 항인지질 항체는 COVID-19의 중증도와 관련이 있습니다Article Published on 2021-09-012022-09-11 Journal: Journal of thrombosis and haemostasis : JTH [Category] SARS, 진단, 치료기술, 치료제, [키워드] accelerate analyzed antibody antiphospholipid antibodies antiphospholipid antibody association Blood Blood coagulation blood coagulation disorder C-reactive protein catastrophic Cell Clinical course Clinical severity Coagulation coagulation disorder Coagulopathy Cohort complex Concentration coronavirus coronavirus disease coronavirus disease 19 COVID-19 COVID-19 patient COVID-19 patients Critical D-dimer dependent on described detectable dimer disease severity endothelial endothelial cells endothelial protein C receptor EPCR expand hallmark Hospitalized hospitalized COVID-19 patients IgG induce Infection Inflammation inflammatory effects Inflammatory response Lipid manifestation marker median Microvascular thrombosis monocyte Monocytes Mortality outcome pathogenic Patient poor prognosis producing Protein protein C prothrombotic prothrombotic syndrome receptor respiratory secreting Severe acute respiratory syndrome severity of COVID-19 signaling pathway single center stroke syndrome thrombosis thrombotic Thrombus thrombus formation venous [DOI] 10.1111/jth.15455 PMC 바로가기 [Article Type] Article
Endothelial Cell Protein C Receptor Deficiency Attenuates Streptococcus pneumoniae- induced Pleural Fibrosisarticle Published on 2021-04-302024-09-01 Journal: American Journal of Respiratory Cell and Molecular Biology [Category] 폐렴구균 감염증, [키워드] endothelial protein C receptor mesothelium pleural fibrosis Streptococcus pneumoniae [Article Type] article
The role of EPCR in the pathogenesis of severe malariaarticle Published on 2016-05-312024-09-01 Journal: Chang Gung Med J [Category] 말라리아, [키워드] endothelial protein C receptor malaria Plasmodium falciparum protein C Vascular endothelium [Article Type] article
Beninese children with cerebral malaria do not develop humoral immunity against the IT4-VAR19-DC8 PfEMP1 variant linked to EPCR and brain endothelial binding베네인 어린이들은 EPCR 및 뇌 내피 결합과 관련된 IT4-VAR19-DC8 PfEMP1 변이에 대한 체액 면역을 개발하지 않습니다.Research Published on 2015-12-082024-08-13 Journal: Malaria Journal [Category] 말라리아, [키워드] cerebral malaria endothelial protein C receptor Immunity Plasmodium falciparum Plasmodium falciparum erythrocyte membrane protein 1 var genes [DOI] 10.1186/s12936-015-1008-5 PMC 바로가기 [Article Type] Research
CD36 and malaria: friends or foes? A decade of data provides some answersarticle Published on 2014-09-302024-09-01 Journal: Trends in Parasitology [Category] 말라리아, [키워드] CD36 endothelial activation endothelial protein C receptor PfEMP1 scavenger receptors [Article Type] article
The endothelial protein C receptor impairs the antibacterial response in murine pneumococcal pneumonia and sepsisEndothelial protein C 수용체는 쥐 폐렴성 폐렴 및 패혈증에서 항균 반응을 저해합니다.journal-article Published on 2014-01-012024-08-04 Journal: Thrombosis and haemostasis [Category] 폐렴구균 감염증, [키워드] Coagulation endothelial protein C receptor Pneumonia Sepsis Streptococcus pneumoniae [DOI] 10.1160/TH13-10-0859 [Article Type] journal-article