Reliability of power output, maximal rate of capillary blood lactate accumulation, and phosphagen contribution time following 15‐s sprint cycling in amateur cyclistsOriginal Article Published on 2024-05-232024-09-05 Journal: Physiological Reports [Category] update2024, [키워드] alactic ATP energy high‐intensity metabolism muscle [DOI] 10.14814/phy2.16086 PMC 바로가기 [Article Type] Original Article
Novel Cu(II)-based metal–organic framework STAM-1 as a sulfur host for Li–S batteriesArticle Published on 2024-04-222024-09-05 Journal: Scientific Reports [Category] update2024, [키워드] Batteries cathode materials energy energy storage Lithium–sulfur battery Materials for energy and catalysis metal–organic framework physical chemistry [DOI] 10.1038/s41598-024-59600-8 PMC 바로가기 [Article Type] Article
A computational approach to biological pathogenicityArticle Published on 2022-11-012022-11-15 Journal: Molecular genetics and genomics : MGG [Category] 바이오마커, [키워드] Accuracy adverse impact approach assessment Biochemistry Biomarkers clinical trial COVID-19 death Digital Digital genomic signature DNA DNA sequence energy event feature genomic Gibbs energy h-distance. Health Host humans hybridization machine machine learning machine learning model methodology microbe mitigate new strain oligonucleotide Other pandemic pathogen pathogenic Pathogenic relationship pathogenicity Pathogens/nonpathogens Perspective predict Quality reducing sensitivity Sensitivity and specificity Sickness specificity structural property [DOI] 10.1007/s00438-022-01951-w PMC 바로가기
The pH Robustness of Bacterial SensingArticle Published on 2022-10-262022-11-16 Journal: mBio [Category] 유전자 메커니즘, [키워드] analyzed appear Bacteria Bacterial bacterial adaptation binding can be used change chaperone chemoreceptor chemotaxis condition conditions COVID-19 pandemic cytosolic demonstrated demonstration determine dimeric domain eight energy Escherichia coli extreme facilitate form Hormones in vivo include information intrinsic isothermal titration calorimetry Ligand ligands mechanism MONITOR Neurotransmitters nine pathway periplasmic pH pH robustness pH value progression Protein Proteins Pseudomonas aeruginosa quorum-sensing receptors recognize reported Research resonance respond response reveal robustness sensing sensor domains signal Signal transduction Signaling TAR tested ultracentrifugation was obtained [DOI] 10.1128/mbio.01650-22 PMC 바로가기
Spectral and theoretical study of SARS-CoV-2 ORF10 protein interaction with endogenous and exogenous macroheterocyclic compoundsSARS-CoV-2 ORF10 단백질과 내인성 및 외인성 거대 이종고리 화합물 상호작용에 대한 스펙트럼 및 이론 연구Article Published on 2022-10-152022-09-11 Journal: Spectrochimica acta. Part A, Molecular and biomole [Category] COVID19(2023년), SARS, 치료제, [키워드] Accessory accessory protein accessory proteins Alpha Antiviral approved bind carried caused cells Chlorin choice complexes Compound coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 criteria drug effective drug effective drugs energy Escherichia coli expressed Features form health problem highest affinity Host immune response in silico infected patient infected patients inhibitor inhibitory initial Interaction macrocycle matter modulate molecular docking MOST ORF10 ORF10 protein Orientation pandemic Pathogenesis Porphyrin Pragmatic precedence Protein protoporphyrin public health recommendation resource SARS-CoV-2 SARS-CoV-2 accessory proteins SARS-CoV-2 coronavirus silico studies Spectral Spectroscopy Spectroscopy. Spread Stage suggested Taking the disease the SARS-CoV-2 Treatment treatment of COVID-19 virucidal virus [DOI] 10.1016/j.saa.2022.121403 PMC 바로가기 [Article Type] Article
In Silico Study towards Repositioning of FDA-Approved Drug Candidates for Anticoronaviral Therapy: Molecular Docking, Molecular Dynamics and Binding Free Energy CalculationsArticle Published on 2022-09-142022-11-15 Journal: Molecules [Category] SARS, 신약개발, 치료제, [키워드] AAK1 addition Anti-COVID-19 Anti-SARS-CoV-2 Activity applied binding binding free energy binding pattern calculation candidate Combination complexes computational modeling digoxin drug drug repositioning drugs Dynamics energy Enzymes evaluated exhibited FDA-approved drug Free greater in silico inhibitor inhibitors methodology molecular molecular docking molecular dynamic simulations MPro niclosamide ouabain PLPro Proscillaridin protease Protein provide RdRP repositioning RNA-dependent RNA polymerase SARS-CoV-2 SARS-CoV-2 main protease screened suggested target targets tested to define [DOI] 10.3390/molecules27185988 PMC 바로가기
All-Atom Simulations of Human ACE2-Spike Protein RBD Complexes for SARS-CoV-2 and Some of its Variants: Nature of Interactions and Free Energy Diagrams for Dissociation of the Protein ComplexesSARS-CoV-2 및 일부 변이체에 대한 인간 ACE2-스파이크 단백질 RBD 복합체의 전체 원자 시뮬레이션: 단백질 복합체의 해리를 위한 상호작용 및 자유 에너지 다이어그램의 특성Article Published on 2022-07-282022-09-11 Journal: The journal of physical chemistry. B [Category] COVID19(2023년), SARS, 변종, [키워드] ACE2 Analysis atomic level average Comparative analysis Diagram dissociation electrostatic electrostatic interaction energy FIVE Free free energy Free energy calculation Free energy calculations Human human Ace2 protein hydrogen Hydrogen bond increase increase in Interaction investigated L452R molecular molecular dynamics mutant N501Y Nature nonspecific pathway positive Protein RBD RBD-ACE2 RBDs Receptor binding domain SARS-CoV-1 SARS-CoV-2 Simulation Spike protein the RBD the spike protein trajectory variant variants variants of SARS-CoV-2 wild type [DOI] 10.1021/acs.jpcb.2c00833 PMC 바로가기 [Article Type] Article
In silico exploration of disulfide derivatives of Ferula foetida oleo-gum (Covexir®) as promising therapeutics against SARS-CoV-2SARS-CoV-2에 대한 유망한 치료제로서 Ferula foetida oleo-gum(Covexir®)의 이황화물 유도체의 실리코 탐사Article Published on 2022-07-012022-09-11 Journal: Computers in biology and medicine [Category] COVID19(2023년), SARS, 변종, [키워드] binding free energy binding mechanism complexes conducted coronavirus COVID-19 Cys145 demonstrated derivative Disulfide drug electron density energy Energy decomposition Ferula Ferula foetida free energy GLN189 His41 inhibitor inhibitors Interaction ligands main role MM/PBGBSA free Energy omicron Omicron variant Quantum mechanics Quantum mechanics calculations. researcher residue SARS-CoV-2 SARS-CoV-2 main protease significantly Spread Vaccine van der Waal variant [DOI] 10.1016/j.compbiomed.2022.105566 PMC 바로가기 [Article Type] Article
Modeling long-term impacts of the COVID-19 pandemic and oil price declines on Gulf oil economiesResearch article Published on 2022-07-012022-10-05 Journal: Economic Modelling [Category] 변종, [키워드] accelerate agreement applied COVID COVID-19 pandemic Critical Decline detrimental Economic sustainability Effect Efficiency energy Energy transition equilibrium Fiscal policy General equilibrium Government Gulf Impact implementation Kuwait Model modeling pandemic Paris potential benefits PROTECT reduce Resilience significantly subsequent targets waned weakened [DOI] 10.1016/j.econmod.2022.105849 [Article Type] Research article
IoMT-fog-cloud based architecture for Covid-19 detectionResearch article Published on 2022-07-012022-10-05 Journal: Biomedical Signal Processing and Control [Category] 변종, 치료기술, [키워드] Accuracy AUC cloud computing CNN coefficient component condition Convolution coronavirus disease COVID-19 dataset deep learning Discrete effective energy Entropy feature Features Fog Computing healthcare implementation IMPROVE information Internet of Medical Things (IoMT) lack latency limit limitation majority Mutation Neuron pandemic patients’ data PCA peak Pneumonia Precision principal Quality Quality of Service (QoS) Ratio recall reduce reduction service Transmission Volume Wavelet wavelet transform [DOI] 10.1016/j.bspc.2022.103715 [Article Type] Research article