Hepatitis B Virus Capsid: The Core in Productive Entry and Covalently Closed Circular DNA FormationReview Published on 2023-02-282023-06-13 Journal: Viruses [Category] B형 간염, [키워드] capsid cccDNA Entry HBC Hepatitis B virus host factors host tropism Infection [DOI] 10.3390/v15030642 PMC 바로가기 [Article Type] Review
Cytoplasmic Tail Truncation Stabilizes S1-S2 Association and Enhances S Protein Incorporation into SARS-CoV-2 Pseudovirionsarticle Published on 2023-02-152024-09-05 Journal: Journal of virology [Category] update2024, [키워드] cytoplasmic tail Entry Infectivity pseudovirus S protein S1 shedding SARS-CoV-2 spike density [DOI] 10.1128/jvi.01650-22 PMC 바로가기 [Article Type] article
Spike mutations contributing to the altered entry preference of SARS-CoV-2 omicron BA.1 and BA.2Article Published on 2022-12-012022-11-16 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 변종, [키워드] change changes in Characteristics circulating cleavage contribute contributing to demonstrated dependent on determinant endosomal entry endosomal entry pathway endosomal pathway Entry facilitate feature Fusogenicity H655Y identify increase investigated less Mutation omicron Omicron BA.1 and BA.2 Pathogenesis pathogenicity plasma membrane predominant Proteases recent reduce reduced retained SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants SARS-CoV-2 WT serine protease spike spike mutation Spike protein spike protein cleavage. subsequent the spike protein TMPRSS2 transmembrane serine protease Virological virus entry [DOI] 10.1080/22221751.2022.2117098 PMC 바로가기
Neuropilin-1 Facilitates Pseudorabies Virus Replication and Viral Glycoprotein B Promotes Its Degradation in a Furin-Dependent MannerArticle Published on 2022-10-262023-07-10 Journal: Journal of Virology [Category] COVID19(2023년), [키워드] C-end Rule Entry glycoprotein B Neuropilin-1 Pathogenesis Pseudorabies virus virulence [DOI] 10.1128/jvi.01318-22 PMC 바로가기
Targeted escape of SARS-CoV-2 in vitro from monoclonal antibody S309, the precursor of sotrovimabArticle Published on 2022-08-242022-11-15 Journal: Frontiers in Immunology [Category] SARS, 진단, [키워드] ACE2 ACE2 binding ACE2 binding site Amino acid angiotensin-converting enzyme 2 antibody Cell cell entry class conserved domain endocytosis Entry epitope escaped Evolution Evolution of SARS-CoV-2 fusion immune Immune escape immunological in vitro infections inhibit SARS-CoV-2 Interaction monoclonal monoclonal antibody not affected pathogenicity plasticity precursor Receptor-binding domain replicated S309 SARS-CoV-2 Sotrovimab susceptible the spike protein vaccination viral strain wild-type SARS-CoV-2 [DOI] 10.3389/fimmu.2022.966236 PMC 바로가기
SARS-CoV-2 spike N-terminal domain modulates TMPRSS2-dependent viral entry and fusogenicitySARS-CoV-2 스파이크 N-말단 도메인은 TMPRSS2 의존성 바이러스 진입 및 융합원성을 조절합니다Article Published on 2022-08-162022-09-11 Journal: Cell Reports [Category] SARS, 변종, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 airway B.1.617 cell-cell fusion characterized chimeric spike chimeric spikes coronavirus CP: Microbiology Delta enrichment Entry exhibit function Fusogenicity increase Infection Interaction lentivirus Lineage lung cell lung cells Microbiology modulate Mutation N-terminal domain NTD NTDs omicron Organoid organoids pseudotyped Region S1/S2 cleavage S1/S2 cleavage efficiency SARS-CoV-2 SARS-CoV-2 spike severe acute respiratory syndrome Coronavirus spike TMPRSS2 transfer variants variants of concern viral entry virus entry VOCs wild-type [DOI] 10.1016/j.celrep.2022.111220 PMC 바로가기 [Article Type] Article
Fungal Secondary Metabolite Exophillic Acid Selectively Inhibits the Entry of Hepatitis B and D VirusesArticle Published on 2022-04-062023-06-12 Journal: Viruses [Category] B형 간염, [키워드] Antiviral Entry exophillic acid HBV HDV inhibitor NTCP [DOI] 10.3390/v14040764 PMC 바로가기
SARS-CoV-2 Entry: At the Crossroads of CD147 and ACE2Communication Published on 2021-06-082022-10-31 Journal: Cells [Category] COVID-19, MERS, SARS, [키워드] ACE2 acute respiratory syndrome affected antibody Basigin Betacoronavirus binding CD147 coronavirus disease Coronavirus infections COVID-19 Emmprin Entry enzyme expressed expression Hepatitis B virus hepatitis C virus Host host cell Human immunodeficiency virus Infection Interference involved Ligand membrane nucleocapsid protein pandemic Protein provided receptor recognize regulate responsible SARS-CoV SARS-CoV-2 SARS-COV-2 infection spike therapeutic target virus infection [DOI] 10.3390/cells10061434 PMC 바로가기 [Article Type] Communication
Drug repurposing screens reveal cell-type-specific entry pathways and FDA-approved drugs active against SARS-Cov-2Article Published on 2021-03-232023-06-15 Journal: Cell Reports [Category] MERS, SARS, [키워드] Antiviral coronavirus cyclophilin cyclosporin drugs Entry HTS SARS2 Screening TMPRSS2 [DOI] 10.1016/j.celrep.2021.108959 PMC 바로가기
HTCC as a Polymeric Inhibitor of SARS-CoV-2 and MERS-CoVSARS-CoV-2 및 MERS-CoV의 고분자 억제제로서의 HTCCArticle Published on 2021-01-282022-09-11 Journal: Journal of Virology [Category] 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 antiviral activity bats block Care characterization China chitosan chloride circulating Cluster Compound Coronaviridae coronavirus demonstrated Entry epithelia escaped ex vivo model HCoV HCoV-229E HCoV-HKU1 HCoV-NL63 HCoV-OC43 Health Health care highly pathogenic HKU1 host cell HTCC human airway human airway epithelia human coronavirus humans in vitro infect information inhibited inhibition inhibitor Interaction life-threatening Local measure mechanism mechanism of action member MERS MERS-CoV Middle East Middle East respiratory syndrome Coronavirus multiorgan failure NL63 Novel coronavirus OC43 pandemic pathogen Polymer Rapid Research respiratory respiratory infection respiratory syndrome coronavirus S protein SARS-CoV-2 SARS-COV-2 infection Seven severe acute respiratory syndrome Coronavirus Spread the S protein virus virus entry viruses [DOI] 10.1128/JVI.01622-20 PMC 바로가기 [Article Type] Article